C3H5_ARATH
ID C3H5_ARATH Reviewed; 757 AA.
AC Q9SY74; Q0WVQ7;
DT 05-MAY-2009, integrated into UniProtKB/Swiss-Prot.
DT 05-MAY-2009, sequence version 2.
DT 25-MAY-2022, entry version 125.
DE RecName: Full=Zinc finger CCCH domain-containing protein 5;
DE Short=AtC3H5;
GN OrderedLocusNames=At1g10320; ORFNames=F14N23.20;
OS Arabidopsis thaliana (Mouse-ear cress).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis.
OX NCBI_TaxID=3702;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. Columbia;
RX PubMed=11130712; DOI=10.1038/35048500;
RA Theologis A., Ecker J.R., Palm C.J., Federspiel N.A., Kaul S., White O.,
RA Alonso J., Altafi H., Araujo R., Bowman C.L., Brooks S.Y., Buehler E.,
RA Chan A., Chao Q., Chen H., Cheuk R.F., Chin C.W., Chung M.K., Conn L.,
RA Conway A.B., Conway A.R., Creasy T.H., Dewar K., Dunn P., Etgu P.,
RA Feldblyum T.V., Feng J.-D., Fong B., Fujii C.Y., Gill J.E., Goldsmith A.D.,
RA Haas B., Hansen N.F., Hughes B., Huizar L., Hunter J.L., Jenkins J.,
RA Johnson-Hopson C., Khan S., Khaykin E., Kim C.J., Koo H.L.,
RA Kremenetskaia I., Kurtz D.B., Kwan A., Lam B., Langin-Hooper S., Lee A.,
RA Lee J.M., Lenz C.A., Li J.H., Li Y.-P., Lin X., Liu S.X., Liu Z.A.,
RA Luros J.S., Maiti R., Marziali A., Militscher J., Miranda M., Nguyen M.,
RA Nierman W.C., Osborne B.I., Pai G., Peterson J., Pham P.K., Rizzo M.,
RA Rooney T., Rowley D., Sakano H., Salzberg S.L., Schwartz J.R., Shinn P.,
RA Southwick A.M., Sun H., Tallon L.J., Tambunga G., Toriumi M.J., Town C.D.,
RA Utterback T., Van Aken S., Vaysberg M., Vysotskaia V.S., Walker M., Wu D.,
RA Yu G., Fraser C.M., Venter J.C., Davis R.W.;
RT "Sequence and analysis of chromosome 1 of the plant Arabidopsis thaliana.";
RL Nature 408:816-820(2000).
RN [2]
RP GENOME REANNOTATION.
RC STRAIN=cv. Columbia;
RX PubMed=27862469; DOI=10.1111/tpj.13415;
RA Cheng C.Y., Krishnakumar V., Chan A.P., Thibaud-Nissen F., Schobel S.,
RA Town C.D.;
RT "Araport11: a complete reannotation of the Arabidopsis thaliana reference
RT genome.";
RL Plant J. 89:789-804(2017).
RN [3]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC STRAIN=cv. Columbia;
RA Totoki Y., Seki M., Ishida J., Nakajima M., Enju A., Kamiya A.,
RA Narusaka M., Shin-i T., Nakagawa M., Sakamoto N., Oishi K., Kohara Y.,
RA Kobayashi M., Toyoda A., Sakaki Y., Sakurai T., Iida K., Akiyama K.,
RA Satou M., Toyoda T., Konagaya A., Carninci P., Kawai J., Hayashizaki Y.,
RA Shinozaki K.;
RT "Large-scale analysis of RIKEN Arabidopsis full-length (RAFL) cDNAs.";
RL Submitted (JUL-2006) to the EMBL/GenBank/DDBJ databases.
RN [4]
RP NOMENCLATURE.
RX PubMed=18221561; DOI=10.1186/1471-2164-9-44;
RA Wang D., Guo Y., Wu C., Yang G., Li Y., Zheng C.;
RT "Genome-wide analysis of CCCH zinc finger family in Arabidopsis and rice.";
RL BMC Genomics 9:44-44(2008).
CC -!- SEQUENCE CAUTION:
CC Sequence=AAD32882.1; Type=Erroneous gene model prediction; Evidence={ECO:0000305};
CC Sequence=BAE98791.1; Type=Miscellaneous discrepancy; Note=Intron retention.; Evidence={ECO:0000305};
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DR EMBL; AC005489; AAD32882.1; ALT_SEQ; Genomic_DNA.
DR EMBL; CP002684; AEE28565.1; -; Genomic_DNA.
DR EMBL; AK226684; BAE98791.1; ALT_SEQ; mRNA.
DR RefSeq; NP_172503.1; NM_100906.1.
DR AlphaFoldDB; Q9SY74; -.
DR SMR; Q9SY74; -.
DR BioGRID; 22811; 1.
DR STRING; 3702.AT1G10320.1; -.
DR iPTMnet; Q9SY74; -.
DR PaxDb; Q9SY74; -.
DR PRIDE; Q9SY74; -.
DR ProteomicsDB; 239083; -.
DR EnsemblPlants; AT1G10320.1; AT1G10320.1; AT1G10320.
DR GeneID; 837571; -.
DR Gramene; AT1G10320.1; AT1G10320.1; AT1G10320.
DR KEGG; ath:AT1G10320; -.
DR Araport; AT1G10320; -.
DR TAIR; locus:2012843; AT1G10320.
DR eggNOG; KOG2202; Eukaryota.
DR HOGENOM; CLU_015692_1_0_1; -.
DR InParanoid; Q9SY74; -.
DR OrthoDB; 1340384at2759; -.
DR PhylomeDB; Q9SY74; -.
DR PRO; PR:Q9SY74; -.
DR Proteomes; UP000006548; Chromosome 1.
DR ExpressionAtlas; Q9SY74; baseline and differential.
DR Genevisible; Q9SY74; AT.
DR GO; GO:0005681; C:spliceosomal complex; IBA:GO_Central.
DR GO; GO:0089701; C:U2AF complex; IBA:GO_Central.
DR GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR GO; GO:0030628; F:pre-mRNA 3'-splice site binding; IBA:GO_Central.
DR GO; GO:0000398; P:mRNA splicing, via spliceosome; IBA:GO_Central.
DR Gene3D; 3.30.70.330; -; 1.
DR InterPro; IPR012677; Nucleotide-bd_a/b_plait_sf.
DR InterPro; IPR035979; RBD_domain_sf.
DR InterPro; IPR000504; RRM_dom.
DR InterPro; IPR003954; RRM_dom_euk.
DR InterPro; IPR009145; U2AF_small.
DR InterPro; IPR000571; Znf_CCCH.
DR PANTHER; PTHR12620; PTHR12620; 1.
DR Pfam; PF00642; zf-CCCH; 2.
DR PRINTS; PR01848; U2AUXFACTOR.
DR SMART; SM00361; RRM_1; 1.
DR SMART; SM00356; ZnF_C3H1; 2.
DR SUPFAM; SSF54928; SSF54928; 1.
DR PROSITE; PS50102; RRM; 1.
DR PROSITE; PS50103; ZF_C3H1; 2.
PE 2: Evidence at transcript level;
KW DNA-binding; Metal-binding; Reference proteome; Repeat; RNA-binding; Zinc;
KW Zinc-finger.
FT CHAIN 1..757
FT /note="Zinc finger CCCH domain-containing protein 5"
FT /id="PRO_0000371966"
FT DOMAIN 295..372
FT /note="RRM"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00176"
FT ZN_FING 240..268
FT /note="C3H1-type 1"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00723"
FT ZN_FING 374..404
FT /note="C3H1-type 2"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00723"
FT REGION 1..127
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 441..757
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1..38
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 51..127
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 458..476
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 486..548
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 555..601
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 608..633
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 643..672
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 679..720
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 733..757
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 757 AA; 89065 MW; 2C15243CC1A93FD7 CRC64;
MEQANEKEEE ERHEEAAGEK ESFEESKEKA AEMSRKEKRK AMKKLKRKQV RKEIAAKERE
EAKAKLNDPA EQERLKAIEE EDARRREKEL KDFEESERAW REAMEIKRKK EEEEEAKREE
EERRWKDLEE LRKLEASGND ECGEDEDGEY EYIEEGPPEI IFQGNEIILK KNKVRVPKKS
VVQVDGHESS NAEFVLQISD RPTSNPLPPG SEASANYQNV SSAQQILESV AQEVPNFGTE
QDKAHCPFHL KTGACRFGQR CSRVHFYPNK SCTLLMKNMY NGPGITWEQD EGLEYTDEEA
ELCYEEFYED VHTEFLKYGE LVNFKVCRNG SFHLKGNVYV HYRSLESAIL AYQSINGRYF
AGKQVNCEFV NISRWKVAIC GEYMKSRLKT CSRGSACNFI HCFRNPGGDY EWADHDRPPP
RFWIHKMTSL FGYSDEKHME HESSGSLNDS ISDLSTDSHR QPSRRSRSRD HDHANVGSTP
SYRSRKYHGD TQDSTREDKL RRHAENCHDG DDSPSRDGSL EREMYKERRY AKDTLHRDSR
WSEHSPGHRV GRKRIHGRYS DDDSADGDDY GRRGTGHKRK PRRGTDSGVQ EQMDNEKDRK
THRSSRKHSR EGSSADKEEG HEHDRVHTVS DKSHRERSKH RHERSSSRYS HEEDSTESRH
HQHKESDKKR SVETSPVGYQ SDKDRDRSKQ RQRYKSDDPE SDQSRKGKRQ SEENSDRETH
KERRHRHRKR RRTQNSDDQN PKESEEVEEE IERWRPV
