TSGA_BUCAP
ID TSGA_BUCAP Reviewed; 387 AA.
AC Q8K942;
DT 15-NOV-2002, integrated into UniProtKB/Swiss-Prot.
DT 01-OCT-2002, sequence version 1.
DT 03-AUG-2022, entry version 104.
DE RecName: Full=Protein TsgA homolog {ECO:0000255|HAMAP-Rule:MF_01044};
GN Name=tsgA {ECO:0000255|HAMAP-Rule:MF_01044}; OrderedLocusNames=BUsg_516;
OS Buchnera aphidicola subsp. Schizaphis graminum (strain Sg).
OC Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
OC Erwiniaceae; Buchnera.
OX NCBI_TaxID=198804;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Sg;
RX PubMed=12089438; DOI=10.1126/science.1071278;
RA Tamas I., Klasson L., Canbaeck B., Naeslund A.K., Eriksson A.-S.,
RA Wernegreen J.J., Sandstroem J.P., Moran N.A., Andersson S.G.E.;
RT "50 million years of genomic stasis in endosymbiotic bacteria.";
RL Science 296:2376-2379(2002).
CC -!- SUBCELLULAR LOCATION: Cell membrane {ECO:0000255|HAMAP-Rule:MF_01044};
CC Multi-pass membrane protein {ECO:0000255|HAMAP-Rule:MF_01044}.
CC -!- SIMILARITY: Belongs to the major facilitator superfamily. TsgA family.
CC {ECO:0000255|HAMAP-Rule:MF_01044}.
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DR EMBL; AE013218; AAM68059.1; -; Genomic_DNA.
DR RefSeq; WP_011054025.1; NC_004061.1.
DR AlphaFoldDB; Q8K942; -.
DR SMR; Q8K942; -.
DR STRING; 198804.BUsg_516; -.
DR EnsemblBacteria; AAM68059; AAM68059; BUsg_516.
DR KEGG; bas:BUsg_516; -.
DR eggNOG; COG0738; Bacteria.
DR HOGENOM; CLU_056916_0_0_6; -.
DR OMA; RFGFVLM; -.
DR OrthoDB; 1121832at2; -.
DR Proteomes; UP000000416; Chromosome.
DR GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0022857; F:transmembrane transporter activity; IEA:InterPro.
DR Gene3D; 1.20.1250.20; -; 2.
DR HAMAP; MF_01044; MFS_TsgA; 1.
DR InterPro; IPR011701; MFS.
DR InterPro; IPR020846; MFS_dom.
DR InterPro; IPR036259; MFS_trans_sf.
DR InterPro; IPR023528; MFS_TsgA.
DR Pfam; PF07690; MFS_1; 1.
DR SUPFAM; SSF103473; SSF103473; 1.
DR PROSITE; PS50850; MFS; 1.
PE 3: Inferred from homology;
KW Cell membrane; Membrane; Transmembrane; Transmembrane helix.
FT CHAIN 1..387
FT /note="Protein TsgA homolog"
FT /id="PRO_0000206492"
FT TRANSMEM 11..31
FT /note="Helical"
FT /evidence="ECO:0000255|HAMAP-Rule:MF_01044"
FT TRANSMEM 47..67
FT /note="Helical"
FT /evidence="ECO:0000255|HAMAP-Rule:MF_01044"
FT TRANSMEM 76..96
FT /note="Helical"
FT /evidence="ECO:0000255|HAMAP-Rule:MF_01044"
FT TRANSMEM 101..121
FT /note="Helical"
FT /evidence="ECO:0000255|HAMAP-Rule:MF_01044"
FT TRANSMEM 134..154
FT /note="Helical"
FT /evidence="ECO:0000255|HAMAP-Rule:MF_01044"
FT TRANSMEM 160..180
FT /note="Helical"
FT /evidence="ECO:0000255|HAMAP-Rule:MF_01044"
FT TRANSMEM 205..225
FT /note="Helical"
FT /evidence="ECO:0000255|HAMAP-Rule:MF_01044"
FT TRANSMEM 243..263
FT /note="Helical"
FT /evidence="ECO:0000255|HAMAP-Rule:MF_01044"
FT TRANSMEM 271..291
FT /note="Helical"
FT /evidence="ECO:0000255|HAMAP-Rule:MF_01044"
FT TRANSMEM 299..319
FT /note="Helical"
FT /evidence="ECO:0000255|HAMAP-Rule:MF_01044"
FT TRANSMEM 331..351
FT /note="Helical"
FT /evidence="ECO:0000255|HAMAP-Rule:MF_01044"
FT TRANSMEM 358..378
FT /note="Helical"
FT /evidence="ECO:0000255|HAMAP-Rule:MF_01044"
SQ SEQUENCE 387 AA; 44022 MW; 07C293450E33BBAE CRC64;
MQNINQIKLT WISFFSYAFT GALIVITGMI MGDIADYFNL SVSEMSNIFT FLNAGILISI
FLNSWLIDLI SIKKQLIFGF LFSIIAILGI VFSTSILLFS INIFILGLVS GITMSIGTFI
ITCLYSGEKR GSQLLLTDSF FSMSGMIFPI ISAYLLDRKI LWYWIYVFLG IIYFLIFILT
VKSHFPVSEE KTKNNNEIKN LNINIILLSI SALLYILGQL SFISWVPQYT TEIININIKK
TGVLVSNFWM AYMIGMWCFS FIIKFFNLQR MFIFLTGSSS VLMYCFIYSK SYLALKYTII
SLGFFSSAIY TIIITLASLE TKKPSAKLIN LILFFGTIGT LLTFIITSPI VAKKGLYTTL
IFSNVLYVIV FFLSCIIFKN SKKKDHC
