ID   TSGA_BUCBP              Reviewed;         388 AA.
AC   Q89A60;
DT   13-APR-2004, integrated into UniProtKB/Swiss-Prot.
DT   01-JUN-2003, sequence version 1.
DT   03-AUG-2022, entry version 97.
DE   RecName: Full=Protein TsgA homolog {ECO:0000255|HAMAP-Rule:MF_01044};
GN   Name=tsgA {ECO:0000255|HAMAP-Rule:MF_01044}; OrderedLocusNames=bbp_477;
OS   Buchnera aphidicola subsp. Baizongia pistaciae (strain Bp).
OC   Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
OC   Erwiniaceae; Buchnera.
OX   NCBI_TaxID=224915;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=Bp;
RX   PubMed=12522265; DOI=10.1073/pnas.0235981100;
RA   van Ham R.C.H.J., Kamerbeek J., Palacios C., Rausell C., Abascal F.,
RA   Bastolla U., Fernandez J.M., Jimenez L., Postigo M., Silva F.J.,
RA   Tamames J., Viguera E., Latorre A., Valencia A., Moran F., Moya A.;
RT   "Reductive genome evolution in Buchnera aphidicola.";
RL   Proc. Natl. Acad. Sci. U.S.A. 100:581-586(2003).
CC   -!- SUBCELLULAR LOCATION: Cell membrane {ECO:0000255|HAMAP-Rule:MF_01044};
CC       Multi-pass membrane protein {ECO:0000255|HAMAP-Rule:MF_01044}.
CC   -!- SIMILARITY: Belongs to the major facilitator superfamily. TsgA family.
CC       {ECO:0000255|HAMAP-Rule:MF_01044}.
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DR   EMBL; AE016826; AAO27183.1; -; Genomic_DNA.
DR   RefSeq; WP_011091584.1; NC_004545.1.
DR   AlphaFoldDB; Q89A60; -.
DR   SMR; Q89A60; -.
DR   STRING; 224915.bbp_477; -.
DR   EnsemblBacteria; AAO27183; AAO27183; bbp_477.
DR   KEGG; bab:bbp_477; -.
DR   eggNOG; COG0738; Bacteria.
DR   HOGENOM; CLU_056916_0_0_6; -.
DR   OMA; RFGFVLM; -.
DR   OrthoDB; 1121832at2; -.
DR   Proteomes; UP000000601; Chromosome.
DR   GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR   GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR   GO; GO:0022857; F:transmembrane transporter activity; IEA:InterPro.
DR   Gene3D; 1.20.1250.20; -; 2.
DR   HAMAP; MF_01044; MFS_TsgA; 1.
DR   InterPro; IPR011701; MFS.
DR   InterPro; IPR020846; MFS_dom.
DR   InterPro; IPR036259; MFS_trans_sf.
DR   InterPro; IPR023528; MFS_TsgA.
DR   Pfam; PF07690; MFS_1; 2.
DR   SUPFAM; SSF103473; SSF103473; 1.
DR   PROSITE; PS50850; MFS; 1.
PE   3: Inferred from homology;
KW   Cell membrane; Membrane; Reference proteome; Transmembrane;
KW   Transmembrane helix.
FT   CHAIN           1..388
FT                   /note="Protein TsgA homolog"
FT                   /id="PRO_0000206493"
FT   TRANSMEM        12..32
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01044"
FT   TRANSMEM        51..71
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01044"
FT   TRANSMEM        77..97
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01044"
FT   TRANSMEM        102..122
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01044"
FT   TRANSMEM        137..157
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01044"
FT   TRANSMEM        163..183
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01044"
FT   TRANSMEM        203..223
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01044"
FT   TRANSMEM        246..266
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01044"
FT   TRANSMEM        272..292
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01044"
FT   TRANSMEM        294..314
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01044"
FT   TRANSMEM        331..351
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01044"
FT   TRANSMEM        356..376
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01044"
SQ   SEQUENCE   388 AA;  43940 MW;  C74663570C17EF80 CRC64;
     MINKSNLIGL TCISFLSYAL TGALITITGI FLENISKYFN IPITDMGNTF TFLNAGILSS
     IFISSWITNI INLKTQLIFG FILTIIATLI LIFSHNLTYF SISMFMLGII SGITMSIGTY
     IITNLYTDQT RASMLLLTDS FFSMSGIIFP IITALIISNN MKWYWVYFII GIIYLIIFLI
     TINTKFPIIY TEISKKRIKT WNFSILCLSI SALLYILGQL SFISWMPEYT MKYIHISINQ
     SSKLVSAFWM AYMVGMWIFS FILKFFDLKK TIITLSGISL FLMSLFNIFY DYALLYIIIL
     SLGFFSSAIY TIIITLASQQ TPLSSPKTIN YILTSGTVGT LLTFIITGPI VQKYGIFSAL
     LVSNILYGIV FFLVIIFATL TKTKPIHD