TSGA_ECOLC
ID TSGA_ECOLC Reviewed; 393 AA.
AC B1IPA0;
DT 20-MAY-2008, integrated into UniProtKB/Swiss-Prot.
DT 29-APR-2008, sequence version 1.
DT 25-MAY-2022, entry version 71.
DE RecName: Full=Protein TsgA {ECO:0000255|HAMAP-Rule:MF_01044};
GN Name=tsgA {ECO:0000255|HAMAP-Rule:MF_01044}; OrderedLocusNames=EcolC_0348;
OS Escherichia coli (strain ATCC 8739 / DSM 1576 / NBRC 3972 / NCIMB 8545 /
OS WDCM 00012 / Crooks).
OC Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
OC Enterobacteriaceae; Escherichia.
OX NCBI_TaxID=481805;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 8739 / DSM 1576 / NBRC 3972 / NCIMB 8545 / WDCM 00012 / Crooks;
RA Copeland A., Lucas S., Lapidus A., Glavina del Rio T., Dalin E., Tice H.,
RA Bruce D., Goodwin L., Pitluck S., Kiss H., Brettin T., Detter J.C., Han C.,
RA Kuske C.R., Schmutz J., Larimer F., Land M., Hauser L., Kyrpides N.,
RA Mikhailova N., Ingram L., Richardson P.;
RT "Complete sequence of Escherichia coli C str. ATCC 8739.";
RL Submitted (FEB-2008) to the EMBL/GenBank/DDBJ databases.
CC -!- SUBCELLULAR LOCATION: Cell inner membrane {ECO:0000255|HAMAP-
CC Rule:MF_01044}; Multi-pass membrane protein {ECO:0000255|HAMAP-
CC Rule:MF_01044}.
CC -!- SIMILARITY: Belongs to the major facilitator superfamily. TsgA family.
CC {ECO:0000255|HAMAP-Rule:MF_01044}.
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DR EMBL; CP000946; ACA76026.1; -; Genomic_DNA.
DR RefSeq; WP_000185258.1; NZ_CP022959.1.
DR AlphaFoldDB; B1IPA0; -.
DR SMR; B1IPA0; -.
DR KEGG; ecl:EcolC_0348; -.
DR HOGENOM; CLU_056916_0_0_6; -.
DR OMA; RFGFVLM; -.
DR GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0022857; F:transmembrane transporter activity; IEA:InterPro.
DR Gene3D; 1.20.1250.20; -; 2.
DR HAMAP; MF_01044; MFS_TsgA; 1.
DR InterPro; IPR011701; MFS.
DR InterPro; IPR020846; MFS_dom.
DR InterPro; IPR036259; MFS_trans_sf.
DR InterPro; IPR023528; MFS_TsgA.
DR Pfam; PF07690; MFS_1; 1.
DR SUPFAM; SSF103473; SSF103473; 1.
DR PROSITE; PS50850; MFS; 1.
PE 3: Inferred from homology;
KW Cell inner membrane; Cell membrane; Membrane; Transmembrane;
KW Transmembrane helix.
FT CHAIN 1..393
FT /note="Protein TsgA"
FT /id="PRO_1000084404"
FT TRANSMEM 11..31
FT /note="Helical"
FT /evidence="ECO:0000255|HAMAP-Rule:MF_01044"
FT TRANSMEM 51..71
FT /note="Helical"
FT /evidence="ECO:0000255|HAMAP-Rule:MF_01044"
FT TRANSMEM 78..98
FT /note="Helical"
FT /evidence="ECO:0000255|HAMAP-Rule:MF_01044"
FT TRANSMEM 101..121
FT /note="Helical"
FT /evidence="ECO:0000255|HAMAP-Rule:MF_01044"
FT TRANSMEM 134..154
FT /note="Helical"
FT /evidence="ECO:0000255|HAMAP-Rule:MF_01044"
FT TRANSMEM 162..182
FT /note="Helical"
FT /evidence="ECO:0000255|HAMAP-Rule:MF_01044"
FT TRANSMEM 206..226
FT /note="Helical"
FT /evidence="ECO:0000255|HAMAP-Rule:MF_01044"
FT TRANSMEM 245..265
FT /note="Helical"
FT /evidence="ECO:0000255|HAMAP-Rule:MF_01044"
FT TRANSMEM 273..293
FT /note="Helical"
FT /evidence="ECO:0000255|HAMAP-Rule:MF_01044"
FT TRANSMEM 297..317
FT /note="Helical"
FT /evidence="ECO:0000255|HAMAP-Rule:MF_01044"
FT TRANSMEM 332..352
FT /note="Helical"
FT /evidence="ECO:0000255|HAMAP-Rule:MF_01044"
FT TRANSMEM 361..381
FT /note="Helical"
FT /evidence="ECO:0000255|HAMAP-Rule:MF_01044"
SQ SEQUENCE 393 AA; 43210 MW; 8E20B7FA891B72FB CRC64;
MTNSNRIKLT WISFLSYALT GALVIVTGMV MGNIADYFNL PVSSMSNTFT FLNAGILISI
FLNAWLMEIV PLKTQLRFGF LLMVLAVAGL MFSHSLALFS TAMFILGVVS GITMSIGTFL
ITQMYEGRQR GSRLLFTDSF FSMAGMIFPM IAAFLLARSI EWYWVYACIG LVYVAIFILT
FGCEFPALGK HAPKTDAPVE KEKWGIGVLF LSVAALCYIL GQLGFISWVP EYAKGLGMSL
NDAGTLVSNF WMSYMVGMWA FSFILRFFDL QRILTVLAGL AAILMYVFNT GTPAHMAWSI
LALGFFSSAI YTTIITLGSQ QTKVPSPKLV NFVLTCGTIG TMLTFVVTGP IVEHSGPQAA
LLTANGLYAV VFVMCFLLGF VSRHRQHNTL TSH
