TSGA_SALHS
ID TSGA_SALHS Reviewed; 393 AA.
AC B4TKP8;
DT 14-APR-2009, integrated into UniProtKB/Swiss-Prot.
DT 23-SEP-2008, sequence version 1.
DT 25-MAY-2022, entry version 62.
DE RecName: Full=Protein TsgA {ECO:0000255|HAMAP-Rule:MF_01044};
GN Name=tsgA {ECO:0000255|HAMAP-Rule:MF_01044}; OrderedLocusNames=SeHA_C3778;
OS Salmonella heidelberg (strain SL476).
OC Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
OC Enterobacteriaceae; Salmonella.
OX NCBI_TaxID=454169;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=SL476;
RX PubMed=21602358; DOI=10.1128/jb.00297-11;
RA Fricke W.F., Mammel M.K., McDermott P.F., Tartera C., White D.G.,
RA Leclerc J.E., Ravel J., Cebula T.A.;
RT "Comparative genomics of 28 Salmonella enterica isolates: evidence for
RT CRISPR-mediated adaptive sublineage evolution.";
RL J. Bacteriol. 193:3556-3568(2011).
CC -!- SUBCELLULAR LOCATION: Cell inner membrane {ECO:0000255|HAMAP-
CC Rule:MF_01044}; Multi-pass membrane protein {ECO:0000255|HAMAP-
CC Rule:MF_01044}.
CC -!- SIMILARITY: Belongs to the major facilitator superfamily. TsgA family.
CC {ECO:0000255|HAMAP-Rule:MF_01044}.
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DR EMBL; CP001120; ACF66424.1; -; Genomic_DNA.
DR RefSeq; WP_000185218.1; NC_011083.1.
DR AlphaFoldDB; B4TKP8; -.
DR SMR; B4TKP8; -.
DR KEGG; seh:SeHA_C3778; -.
DR HOGENOM; CLU_056916_0_0_6; -.
DR OMA; RFGFVLM; -.
DR Proteomes; UP000001866; Chromosome.
DR GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0022857; F:transmembrane transporter activity; IEA:InterPro.
DR Gene3D; 1.20.1250.20; -; 2.
DR HAMAP; MF_01044; MFS_TsgA; 1.
DR InterPro; IPR011701; MFS.
DR InterPro; IPR020846; MFS_dom.
DR InterPro; IPR036259; MFS_trans_sf.
DR InterPro; IPR023528; MFS_TsgA.
DR Pfam; PF07690; MFS_1; 1.
DR SUPFAM; SSF103473; SSF103473; 1.
DR PROSITE; PS50850; MFS; 1.
PE 3: Inferred from homology;
KW Cell inner membrane; Cell membrane; Membrane; Transmembrane;
KW Transmembrane helix.
FT CHAIN 1..393
FT /note="Protein TsgA"
FT /id="PRO_1000136149"
FT TRANSMEM 11..31
FT /note="Helical"
FT /evidence="ECO:0000255|HAMAP-Rule:MF_01044"
FT TRANSMEM 51..71
FT /note="Helical"
FT /evidence="ECO:0000255|HAMAP-Rule:MF_01044"
FT TRANSMEM 78..98
FT /note="Helical"
FT /evidence="ECO:0000255|HAMAP-Rule:MF_01044"
FT TRANSMEM 101..121
FT /note="Helical"
FT /evidence="ECO:0000255|HAMAP-Rule:MF_01044"
FT TRANSMEM 134..154
FT /note="Helical"
FT /evidence="ECO:0000255|HAMAP-Rule:MF_01044"
FT TRANSMEM 162..182
FT /note="Helical"
FT /evidence="ECO:0000255|HAMAP-Rule:MF_01044"
FT TRANSMEM 206..226
FT /note="Helical"
FT /evidence="ECO:0000255|HAMAP-Rule:MF_01044"
FT TRANSMEM 245..265
FT /note="Helical"
FT /evidence="ECO:0000255|HAMAP-Rule:MF_01044"
FT TRANSMEM 273..293
FT /note="Helical"
FT /evidence="ECO:0000255|HAMAP-Rule:MF_01044"
FT TRANSMEM 298..318
FT /note="Helical"
FT /evidence="ECO:0000255|HAMAP-Rule:MF_01044"
FT TRANSMEM 332..352
FT /note="Helical"
FT /evidence="ECO:0000255|HAMAP-Rule:MF_01044"
FT TRANSMEM 361..381
FT /note="Helical"
FT /evidence="ECO:0000255|HAMAP-Rule:MF_01044"
SQ SEQUENCE 393 AA; 43146 MW; 35F8363F5CC6BFD6 CRC64;
MTNSNRIKLT WISFLSYALT GALVIVTGMV MGNIADYFHL PVSSMSNTFT FLNAGILISI
FLNAWLMEIV PLKTQLRFGF ILMVLAVAGL MFSHSLALFS AAMFVLGLVS GITMSIGTFL
ITQLYEGRQR GSRLLFTDSF FSMAGMIFPM VAAFLLARSI EWYWVYACIG LVYLAIFILT
FGCEFPALGK HAQHSQAPVV KEKWGIGVLF LAVAALCYIL GQLGFISWVP EYAKGLGMSL
NDAGALVSDF WMSYMFGMWA FSFILRFFDL QRILTVLAGM AAVLMYLFIT GTQAHMPWFI
LTLGFFSSAI YTSIITLGSQ QTKVASPKLV NFILTCGTIG TMLTFVVTGP IVAHSGPQAA
LLTANGLYAV VFVMCFALGF VSRHRQHSAP ATH
