ID   TSGA_SALNS              Reviewed;         393 AA.
AC   B4SVH5;
DT   14-APR-2009, integrated into UniProtKB/Swiss-Prot.
DT   23-SEP-2008, sequence version 1.
DT   25-MAY-2022, entry version 60.
DE   RecName: Full=Protein TsgA {ECO:0000255|HAMAP-Rule:MF_01044};
GN   Name=tsgA {ECO:0000255|HAMAP-Rule:MF_01044};
GN   OrderedLocusNames=SNSL254_A3743;
OS   Salmonella newport (strain SL254).
OC   Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
OC   Enterobacteriaceae; Salmonella.
OX   NCBI_TaxID=423368;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=SL254;
RX   PubMed=21602358; DOI=10.1128/jb.00297-11;
RA   Fricke W.F., Mammel M.K., McDermott P.F., Tartera C., White D.G.,
RA   Leclerc J.E., Ravel J., Cebula T.A.;
RT   "Comparative genomics of 28 Salmonella enterica isolates: evidence for
RT   CRISPR-mediated adaptive sublineage evolution.";
RL   J. Bacteriol. 193:3556-3568(2011).
CC   -!- SUBCELLULAR LOCATION: Cell inner membrane {ECO:0000255|HAMAP-
CC       Rule:MF_01044}; Multi-pass membrane protein {ECO:0000255|HAMAP-
CC       Rule:MF_01044}.
CC   -!- SIMILARITY: Belongs to the major facilitator superfamily. TsgA family.
CC       {ECO:0000255|HAMAP-Rule:MF_01044}.
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DR   EMBL; CP001113; ACF65129.1; -; Genomic_DNA.
DR   RefSeq; WP_000185267.1; NZ_CCMR01000004.1.
DR   AlphaFoldDB; B4SVH5; -.
DR   SMR; B4SVH5; -.
DR   EnsemblBacteria; ACF65129; ACF65129; SNSL254_A3743.
DR   KEGG; see:SNSL254_A3743; -.
DR   HOGENOM; CLU_056916_0_0_6; -.
DR   OMA; RFGFVLM; -.
DR   Proteomes; UP000008824; Chromosome.
DR   GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR   GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR   GO; GO:0022857; F:transmembrane transporter activity; IEA:InterPro.
DR   Gene3D; 1.20.1250.20; -; 2.
DR   HAMAP; MF_01044; MFS_TsgA; 1.
DR   InterPro; IPR011701; MFS.
DR   InterPro; IPR020846; MFS_dom.
DR   InterPro; IPR036259; MFS_trans_sf.
DR   InterPro; IPR023528; MFS_TsgA.
DR   Pfam; PF07690; MFS_1; 1.
DR   SUPFAM; SSF103473; SSF103473; 1.
DR   PROSITE; PS50850; MFS; 1.
PE   3: Inferred from homology;
KW   Cell inner membrane; Cell membrane; Membrane; Transmembrane;
KW   Transmembrane helix.
FT   CHAIN           1..393
FT                   /note="Protein TsgA"
FT                   /id="PRO_1000136150"
FT   TRANSMEM        11..31
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01044"
FT   TRANSMEM        51..71
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01044"
FT   TRANSMEM        78..98
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01044"
FT   TRANSMEM        101..121
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01044"
FT   TRANSMEM        134..154
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01044"
FT   TRANSMEM        162..182
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01044"
FT   TRANSMEM        206..226
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01044"
FT   TRANSMEM        245..265
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01044"
FT   TRANSMEM        273..293
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01044"
FT   TRANSMEM        298..318
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01044"
FT   TRANSMEM        332..352
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01044"
FT   TRANSMEM        361..381
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01044"
SQ   SEQUENCE   393 AA;  43151 MW;  B9477E0819C0415C CRC64;
     MTNSNRIKLT WISFLSYALT GALVIVTGMV MGNIADYFQL PVSSMSNTFT FLNAGILISI
     FLNAWLMEII PLKTQLRFGF ILMVLAVAGL MFSHSLALFS AAMFVLGLVS GITMSIGTFL
     ITQLYEGRQR GSRLLFTDSF FSMAGMIFPM VAAFLLARSI EWYWVYACIG LVYLAIFILT
     FGCEFPALGK HAQHSQAPVV KEKWGIGVLF LAVAALCYIL GQLGFISWVP EYAKGLGMSL
     NDAGALVSDF WMSYMFGMWA FSFILRFFDL QRILTVLAGM AAVLMYLFIT GTQAHMPWFI
     LTLGFFSSAI YTSIITLGSQ QTKVASPKLV NFILTCGTIG TMLTFVVTGP IVAHSGPQAA
     LLTANGLYAV VFVMCFALGF VSRHRQHSAP ATH