ID   TSGA_SERP5              Reviewed;         394 AA.
AC   A8GKP6;
DT   05-FEB-2008, integrated into UniProtKB/Swiss-Prot.
DT   13-NOV-2007, sequence version 1.
DT   25-MAY-2022, entry version 74.
DE   RecName: Full=Protein TsgA homolog {ECO:0000255|HAMAP-Rule:MF_01044};
GN   Name=tsgA {ECO:0000255|HAMAP-Rule:MF_01044}; OrderedLocusNames=Spro_4593;
OS   Serratia proteamaculans (strain 568).
OC   Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
OC   Yersiniaceae; Serratia.
OX   NCBI_TaxID=399741;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=568;
RG   US DOE Joint Genome Institute;
RA   Copeland A., Lucas S., Lapidus A., Barry K., Glavina del Rio T., Dalin E.,
RA   Tice H., Pitluck S., Chain P., Malfatti S., Shin M., Vergez L., Schmutz J.,
RA   Larimer F., Land M., Hauser L., Kyrpides N., Kim E., Taghavi S., Newman L.,
RA   Vangronsveld J., van der Lelie D., Richardson P.;
RT   "Complete sequence of chromosome of Serratia proteamaculans 568.";
RL   Submitted (SEP-2007) to the EMBL/GenBank/DDBJ databases.
CC   -!- SUBCELLULAR LOCATION: Cell inner membrane {ECO:0000255|HAMAP-
CC       Rule:MF_01044}; Multi-pass membrane protein {ECO:0000255|HAMAP-
CC       Rule:MF_01044}.
CC   -!- SIMILARITY: Belongs to the major facilitator superfamily. TsgA family.
CC       {ECO:0000255|HAMAP-Rule:MF_01044}.
CC   ---------------------------------------------------------------------------
CC   Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC   Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC   ---------------------------------------------------------------------------
DR   EMBL; CP000826; ABV43686.1; -; Genomic_DNA.
DR   RefSeq; WP_012147270.1; NC_009832.1.
DR   AlphaFoldDB; A8GKP6; -.
DR   SMR; A8GKP6; -.
DR   STRING; 399741.Spro_4593; -.
DR   EnsemblBacteria; ABV43686; ABV43686; Spro_4593.
DR   KEGG; spe:Spro_4593; -.
DR   eggNOG; COG0738; Bacteria.
DR   HOGENOM; CLU_056916_0_0_6; -.
DR   OMA; RFGFVLM; -.
DR   OrthoDB; 1121832at2; -.
DR   GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR   GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR   GO; GO:0022857; F:transmembrane transporter activity; IEA:InterPro.
DR   Gene3D; 1.20.1250.20; -; 2.
DR   HAMAP; MF_01044; MFS_TsgA; 1.
DR   InterPro; IPR011701; MFS.
DR   InterPro; IPR020846; MFS_dom.
DR   InterPro; IPR036259; MFS_trans_sf.
DR   InterPro; IPR023528; MFS_TsgA.
DR   Pfam; PF07690; MFS_1; 1.
DR   SUPFAM; SSF103473; SSF103473; 1.
DR   PROSITE; PS50850; MFS; 1.
PE   3: Inferred from homology;
KW   Cell inner membrane; Cell membrane; Membrane; Transmembrane;
KW   Transmembrane helix.
FT   CHAIN           1..394
FT                   /note="Protein TsgA homolog"
FT                   /id="PRO_1000064251"
FT   TRANSMEM        11..31
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01044"
FT   TRANSMEM        51..71
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01044"
FT   TRANSMEM        76..96
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01044"
FT   TRANSMEM        101..121
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01044"
FT   TRANSMEM        134..154
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01044"
FT   TRANSMEM        162..182
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01044"
FT   TRANSMEM        206..226
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01044"
FT   TRANSMEM        251..271
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01044"
FT   TRANSMEM        274..294
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01044"
FT   TRANSMEM        302..322
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01044"
FT   TRANSMEM        334..354
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01044"
FT   TRANSMEM        363..383
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01044"
SQ   SEQUENCE   394 AA;  43291 MW;  4C16753545D6DF72 CRC64;
     MNDSNRLRLT WISYFSYALT GALVIVTGMV MGNIAEYFNL PVSSMSNTFT FLNAGILISI
     FLNAWLMEII PLKRQLMFGF VLMVLAIAGL MLGKSLTMFS LCMFILGVVS GITMSIGTFL
     ITHMYAGRQR GSRLLFTDSF FSMAGMIFPI VAAMLLARQI GWYWVYACIG LLYVGIFVLT
     LFSEFPVLGN KGADAGQPVV KEKWGIGVLF LSIAALCYIL GQLGFIQWVP EYATKSFGMD
     ISQAGKLVSD FWTSYMIGMW VFSFILRFFD LQRIVTILAA LATGAMYLFV STDNPEHLSY
     YIMALGFVSS AIYTTLITLG SLQTKVSSPK LVNFILTCGT IGTMLTFVVT GPIVAKGGAH
     AALTTANGLY LAVFVMCLLL GFVTKHRSHG HVTH