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TSGA_YERE8
ID   TSGA_YERE8              Reviewed;         394 AA.
AC   A1JSB0;
DT   05-FEB-2008, integrated into UniProtKB/Swiss-Prot.
DT   06-FEB-2007, sequence version 1.
DT   25-MAY-2022, entry version 77.
DE   RecName: Full=Protein TsgA homolog {ECO:0000255|HAMAP-Rule:MF_01044};
GN   Name=tsgA {ECO:0000255|HAMAP-Rule:MF_01044}; OrderedLocusNames=YE3963;
OS   Yersinia enterocolitica serotype O:8 / biotype 1B (strain NCTC 13174 /
OS   8081).
OC   Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
OC   Yersiniaceae; Yersinia.
OX   NCBI_TaxID=393305;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=NCTC 13174 / 8081;
RX   PubMed=17173484; DOI=10.1371/journal.pgen.0020206;
RA   Thomson N.R., Howard S., Wren B.W., Holden M.T.G., Crossman L.,
RA   Challis G.L., Churcher C., Mungall K., Brooks K., Chillingworth T.,
RA   Feltwell T., Abdellah Z., Hauser H., Jagels K., Maddison M., Moule S.,
RA   Sanders M., Whitehead S., Quail M.A., Dougan G., Parkhill J.,
RA   Prentice M.B.;
RT   "The complete genome sequence and comparative genome analysis of the high
RT   pathogenicity Yersinia enterocolitica strain 8081.";
RL   PLoS Genet. 2:2039-2051(2006).
CC   -!- SUBCELLULAR LOCATION: Cell inner membrane {ECO:0000255|HAMAP-
CC       Rule:MF_01044}; Multi-pass membrane protein {ECO:0000255|HAMAP-
CC       Rule:MF_01044}.
CC   -!- SIMILARITY: Belongs to the major facilitator superfamily. TsgA family.
CC       {ECO:0000255|HAMAP-Rule:MF_01044}.
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DR   EMBL; AM286415; CAL13982.1; -; Genomic_DNA.
DR   RefSeq; WP_011817338.1; NC_008800.1.
DR   RefSeq; YP_001008108.1; NC_008800.1.
DR   AlphaFoldDB; A1JSB0; -.
DR   SMR; A1JSB0; -.
DR   STRING; 393305.YE3963; -.
DR   EnsemblBacteria; CAL13982; CAL13982; YE3963.
DR   KEGG; yen:YE3963; -.
DR   PATRIC; fig|393305.7.peg.4216; -.
DR   eggNOG; COG0738; Bacteria.
DR   HOGENOM; CLU_056916_0_0_6; -.
DR   OMA; RFGFVLM; -.
DR   Proteomes; UP000000642; Chromosome.
DR   GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR   GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR   GO; GO:0022857; F:transmembrane transporter activity; IEA:InterPro.
DR   Gene3D; 1.20.1250.20; -; 2.
DR   HAMAP; MF_01044; MFS_TsgA; 1.
DR   InterPro; IPR011701; MFS.
DR   InterPro; IPR020846; MFS_dom.
DR   InterPro; IPR036259; MFS_trans_sf.
DR   InterPro; IPR023528; MFS_TsgA.
DR   Pfam; PF07690; MFS_1; 1.
DR   SUPFAM; SSF103473; SSF103473; 1.
DR   PROSITE; PS50850; MFS; 1.
PE   3: Inferred from homology;
KW   Cell inner membrane; Cell membrane; Membrane; Transmembrane;
KW   Transmembrane helix.
FT   CHAIN           1..394
FT                   /note="Protein TsgA homolog"
FT                   /id="PRO_1000064256"
FT   TRANSMEM        11..31
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01044"
FT   TRANSMEM        51..71
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01044"
FT   TRANSMEM        76..96
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01044"
FT   TRANSMEM        101..121
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01044"
FT   TRANSMEM        134..154
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01044"
FT   TRANSMEM        162..182
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01044"
FT   TRANSMEM        206..226
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01044"
FT   TRANSMEM        246..266
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01044"
FT   TRANSMEM        274..294
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01044"
FT   TRANSMEM        302..322
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01044"
FT   TRANSMEM        334..354
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01044"
FT   TRANSMEM        363..383
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01044"
SQ   SEQUENCE   394 AA;  43682 MW;  B82343D1D254AF95 CRC64;
     MNNSNRLRLT WISYFSYALT GALVIVTGMV MGNIAEYFNL PIASMSNTFT FLNAGILISI
     FLNAWLMEII PLKRQLVFGF ILMLIAIAGL MVGHNLMIFS ISMFILGVVS GITMSIGTFL
     ITHMYEGRQR GSRLLFTDSF FSMAGMIFPV AAAILLARHI EWYWVYACIG LLYVGIFVLT
     LCSEFPVLGH KATDQSKPVA KEKWGMGVLF LAIAALCYIL GQLGFIQWVP EYATKTFNMD
     ISQAGQLVSN FWISYMIGMW VFSFILRFFD LQRIVTVLAA LATLSMYMFV STNNPEHLSY
     YILALGFVSS AIYTTLITLG SLQTKVSSPK LVNFILTCGT VGTMLTFVVT GPIVANSGVH
     AALATANGLY LTVFVMCLIL GFFTKHRSHG HVTH
 
 
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