C3H63_ORYSJ
ID C3H63_ORYSJ Reviewed; 444 AA.
AC Q2R4J4; Q0ISS4;
DT 02-SEP-2008, integrated into UniProtKB/Swiss-Prot.
DT 11-JUL-2006, sequence version 2.
DT 03-AUG-2022, entry version 82.
DE RecName: Full=Zinc finger CCCH domain-containing protein 63;
DE Short=OsC3H63;
GN OrderedLocusNames=Os11g0472000, LOC_Os11g28270;
OS Oryza sativa subsp. japonica (Rice).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; Liliopsida; Poales; Poaceae; BOP clade;
OC Oryzoideae; Oryzeae; Oryzinae; Oryza; Oryza sativa.
OX NCBI_TaxID=39947;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. Nipponbare;
RX PubMed=16188032; DOI=10.1186/1741-7007-3-20;
RG The rice chromosomes 11 and 12 sequencing consortia;
RT "The sequence of rice chromosomes 11 and 12, rich in disease resistance
RT genes and recent gene duplications.";
RL BMC Biol. 3:20-20(2005).
RN [2]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. Nipponbare;
RX PubMed=16100779; DOI=10.1038/nature03895;
RG International rice genome sequencing project (IRGSP);
RT "The map-based sequence of the rice genome.";
RL Nature 436:793-800(2005).
RN [3]
RP GENOME REANNOTATION.
RC STRAIN=cv. Nipponbare;
RX PubMed=18089549; DOI=10.1093/nar/gkm978;
RG The rice annotation project (RAP);
RT "The rice annotation project database (RAP-DB): 2008 update.";
RL Nucleic Acids Res. 36:D1028-D1033(2008).
RN [4]
RP GENOME REANNOTATION.
RC STRAIN=cv. Nipponbare;
RX PubMed=24280374; DOI=10.1186/1939-8433-6-4;
RA Kawahara Y., de la Bastide M., Hamilton J.P., Kanamori H., McCombie W.R.,
RA Ouyang S., Schwartz D.C., Tanaka T., Wu J., Zhou S., Childs K.L.,
RA Davidson R.M., Lin H., Quesada-Ocampo L., Vaillancourt B., Sakai H.,
RA Lee S.S., Kim J., Numa H., Itoh T., Buell C.R., Matsumoto T.;
RT "Improvement of the Oryza sativa Nipponbare reference genome using next
RT generation sequence and optical map data.";
RL Rice 6:4-4(2013).
RN [5]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 2).
RC STRAIN=cv. Nipponbare;
RX PubMed=12869764; DOI=10.1126/science.1081288;
RG The rice full-length cDNA consortium;
RT "Collection, mapping, and annotation of over 28,000 cDNA clones from
RT japonica rice.";
RL Science 301:376-379(2003).
RN [6]
RP NOMENCLATURE.
RX PubMed=18221561; DOI=10.1186/1471-2164-9-44;
RA Wang D., Guo Y., Wu C., Yang G., Li Y., Zheng C.;
RT "Genome-wide analysis of CCCH zinc finger family in Arabidopsis and rice.";
RL BMC Genomics 9:44-44(2008).
CC -!- ALTERNATIVE PRODUCTS:
CC Event=Alternative splicing; Named isoforms=2;
CC Name=1;
CC IsoId=Q2R4J4-1; Sequence=Displayed;
CC Name=2;
CC IsoId=Q2R4J4-2; Sequence=VSP_035023;
CC -!- SEQUENCE CAUTION:
CC Sequence=BAF28241.1; Type=Erroneous initiation; Evidence={ECO:0000305};
CC -!- SEQUENCE CAUTION: [Isoform 2]:
CC Sequence=AK110345; Type=Frameshift; Evidence={ECO:0000305};
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; DP000010; ABA93650.2; -; Genomic_DNA.
DR EMBL; AP008217; BAF28241.1; ALT_INIT; Genomic_DNA.
DR EMBL; AP014967; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; AK110345; -; NOT_ANNOTATED_CDS; mRNA.
DR RefSeq; XP_015617449.1; XM_015761963.1. [Q2R4J4-1]
DR AlphaFoldDB; Q2R4J4; -.
DR STRING; 4530.OS11T0472000-01; -.
DR PaxDb; Q2R4J4; -.
DR PRIDE; Q2R4J4; -.
DR GeneID; 4350492; -.
DR KEGG; osa:4350492; -.
DR eggNOG; KOG1677; Eukaryota.
DR HOGENOM; CLU_033292_2_1_1; -.
DR InParanoid; Q2R4J4; -.
DR Proteomes; UP000000763; Chromosome 11.
DR Proteomes; UP000059680; Chromosome 11.
DR Genevisible; Q2R4J4; OS.
DR GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR GO; GO:0003729; F:mRNA binding; IBA:GO_Central.
DR InterPro; IPR000571; Znf_CCCH.
DR InterPro; IPR036855; Znf_CCCH_sf.
DR Pfam; PF00642; zf-CCCH; 5.
DR SMART; SM00356; ZnF_C3H1; 5.
DR SUPFAM; SSF90229; SSF90229; 5.
DR PROSITE; PS50103; ZF_C3H1; 5.
PE 2: Evidence at transcript level;
KW Alternative splicing; DNA-binding; Metal-binding; Reference proteome;
KW Repeat; Zinc; Zinc-finger.
FT CHAIN 1..444
FT /note="Zinc finger CCCH domain-containing protein 63"
FT /id="PRO_0000346854"
FT ZN_FING 56..84
FT /note="C3H1-type 1"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00723"
FT ZN_FING 101..129
FT /note="C3H1-type 2"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00723"
FT ZN_FING 147..175
FT /note="C3H1-type 3"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00723"
FT ZN_FING 309..337
FT /note="C3H1-type 4"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00723"
FT ZN_FING 355..383
FT /note="C3H1-type 5"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00723"
FT REGION 251..276
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 405..444
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 414..437
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT VAR_SEQ 1..38
FT /note="Missing (in isoform 2)"
FT /evidence="ECO:0000303|PubMed:12869764"
FT /id="VSP_035023"
FT CONFLICT 281
FT /note="D -> G (in Ref. 5; AK110345)"
FT /evidence="ECO:0000305"
SQ SEQUENCE 444 AA; 48006 MW; D3C0DA712073158B CRC64;
MAAAPSAGGV GEGSSSSAAA AAAAAAATIG PHVVDEEAMW QMNLGEAMEA GPYPERIGEP
DCSYYMRTGL CRFGMTCKFN HPADRKMAVA AARMKGEYPQ RIGQPECQYY LKTGTCKFGA
TCKFHHPREK AAIATRVQLN ALGYPLRPNE KECAYYLRTG QCKFGSTCKF HHPQPSNTMV
AVRGSVYSPG QSVTSPSQHT YPGAVTNWPL SRSASFIASP RWPGHSSYAQ VIVPPGLVQV
PGWNPYAAQI GSSSSDDQQR TAGGAQYYTG SRHSETPNMG DQGMFSSYQA GSVPLGLYTV
QRESIFPERP DQPECQFYMK TGDCKFGAVC KFHHPKERII PTPNCALSSL GLPLRPGEPI
CTFYSRYGIC KFGPNCKFDH PMGTVMYGLA TSPTGDVSAR RMLAPVPAHS EVSPDNVSGR
SRRITHSDSQ QIPSGERGTE REAS