ID   TSGBD_HALVD             Reviewed;         380 AA.
AC   D4GPW2; Q9Y8J9;
DT   06-FEB-2013, integrated into UniProtKB/Swiss-Prot.
DT   18-MAY-2010, sequence version 1.
DT   25-MAY-2022, entry version 53.
DE   RecName: Full=Glucose ABC transporter permease protein TsgB13;
GN   Name=tsgB13; OrderedLocusNames=HVO_B0315;
OS   Haloferax volcanii (strain ATCC 29605 / DSM 3757 / JCM 8879 / NBRC 14742 /
OS   NCIMB 2012 / VKM B-1768 / DS2) (Halobacterium volcanii).
OG   Plasmid pHV3.
OC   Archaea; Euryarchaeota; Stenosarchaea group; Halobacteria; Haloferacales;
OC   Haloferacaceae; Haloferax.
OX   NCBI_TaxID=309800;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 29605 / DSM 3757 / JCM 8879 / NBRC 14742 / NCIMB 2012 / VKM
RC   B-1768 / DS2; PLASMID=pHV3;
RX   PubMed=20333302; DOI=10.1371/journal.pone.0009605;
RA   Hartman A.L., Norais C., Badger J.H., Delmas S., Haldenby S., Madupu R.,
RA   Robinson J., Khouri H., Ren Q., Lowe T.M., Maupin-Furlow J.,
RA   Pohlschroder M., Daniels C., Pfeiffer F., Allers T., Eisen J.A.;
RT   "The complete genome sequence of Haloferax volcanii DS2, a model
RT   archaeon.";
RL   PLoS ONE 5:E9605-E9605(2010).
RN   [2]
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA] OF 1-140, FUNCTION, AND DISRUPTION
RP   PHENOTYPE.
RC   STRAIN=DS2 / WR 340;
RX   PubMed=10430572; DOI=10.1093/genetics/152.4.1417;
RA   Wanner C., Soppa J.;
RT   "Genetic identification of three ABC transporters as essential elements for
RT   nitrate respiration in Haloferax volcanii.";
RL   Genetics 152:1417-1428(1999).
CC   -!- FUNCTION: Part of an ABC transporter complex involved in glucose import
CC       (Probable). Responsible for the translocation of the substrate across
CC       the membrane (By similarity). {ECO:0000250,
CC       ECO:0000269|PubMed:10430572, ECO:0000305}.
CC   -!- SUBUNIT: The complex is composed of two ATP-binding proteins (TsgD13),
CC       two transmembrane proteins (TsgB13 and TsgC13) and a solute-binding
CC       protein (TsgA13). {ECO:0000305}.
CC   -!- SUBCELLULAR LOCATION: Cell membrane {ECO:0000305}; Multi-pass membrane
CC       protein {ECO:0000305}.
CC   -!- DISRUPTION PHENOTYPE: Mutant with a disruption within tsgB13 or tsgD13
CC       cannot use glucose for nitrate respirative growth. However, the mutant
CC       can grow aerobically using glucose as the sole energy source.
CC       {ECO:0000269|PubMed:10430572}.
CC   -!- SIMILARITY: Belongs to the binding-protein-dependent transport system
CC       permease family. {ECO:0000305}.
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DR   EMBL; CP001953; ADE01501.1; -; Genomic_DNA.
DR   EMBL; AJ238879; CAB42545.1; -; Genomic_DNA.
DR   RefSeq; WP_004041227.1; NZ_AOHU01000021.1.
DR   AlphaFoldDB; D4GPW2; -.
DR   STRING; 309800.C498_02090; -.
DR   EnsemblBacteria; ADE01501; ADE01501; HVO_B0315.
DR   GeneID; 8919186; -.
DR   KEGG; hvo:HVO_B0315; -.
DR   eggNOG; arCOG00260; Archaea.
DR   HOGENOM; CLU_040769_0_0_2; -.
DR   OMA; WFSWQNT; -.
DR   OrthoDB; 57686at2157; -.
DR   Proteomes; UP000008243; Plasmid pHV3.
DR   GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR   GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR   GO; GO:0022857; F:transmembrane transporter activity; IEA:InterPro.
DR   GO; GO:0008643; P:carbohydrate transport; IEA:UniProtKB-KW.
DR   InterPro; IPR001851; ABC_transp_permease.
DR   Pfam; PF02653; BPD_transp_2; 1.
PE   3: Inferred from homology;
KW   Cell membrane; Membrane; Plasmid; Reference proteome; Sugar transport;
KW   Transmembrane; Transmembrane helix; Transport.
FT   CHAIN           1..380
FT                   /note="Glucose ABC transporter permease protein TsgB13"
FT                   /id="PRO_0000420945"
FT   TRANSMEM        20..40
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        59..81
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        94..114
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        115..135
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        148..166
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        202..222
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        255..275
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        282..301
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        305..325
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        328..348
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
SQ   SEQUENCE   380 AA;  39651 MW;  2D28E4B71D28F503 CRC64;
     MNVELQLDPR RTVPAWLAYG TPVLTVLAAL AVGGVALVAL NVDPVDAYGV MFVETLTSQF
     GLTEVLVRAV PLILAGLAVY LPLKAGLFNI GAEGQLLLGA LAGTWVAVNV SLPAVALLPL
     MFLAACVAGA FWAGIPAWLR AKWDVNEIIT SLLLTFVAQE LQSYLLRGPM QGGTGNFPQS
     ARFSDAATLP PLAGLVPGGE SIPLFADVHA GLLVAVAAVV ATYVVMTKTR LGFEVTFVGS
     NDEAARQAGM SRHTVYLFVF LLGGAFAALG GIAEIAGSQG RFRAAFAPGY GFTAIPIALL
     GRNSAVKVTL AGLFFAVLFV GGSSVEVAFG VPAALVEIIQ ALVILFLITS EFFKRYRVGI
     AFDRRGNDAP ADATGGDARW