C3H66_ARATH
ID C3H66_ARATH Reviewed; 607 AA.
AC Q9LUZ4;
DT 05-MAY-2009, integrated into UniProtKB/Swiss-Prot.
DT 01-OCT-2000, sequence version 1.
DT 25-MAY-2022, entry version 145.
DE RecName: Full=Zinc finger CCCH domain-containing protein 66;
DE Short=AtC3H66;
GN OrderedLocusNames=At5g58620; ORFNames=MZN1.16, MZN1.8;
OS Arabidopsis thaliana (Mouse-ear cress).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis.
OX NCBI_TaxID=3702;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. Columbia;
RX PubMed=10718197; DOI=10.1093/dnares/7.1.31;
RA Sato S., Nakamura Y., Kaneko T., Katoh T., Asamizu E., Kotani H.,
RA Tabata S.;
RT "Structural analysis of Arabidopsis thaliana chromosome 5. X. Sequence
RT features of the regions of 3,076,755 bp covered by sixty P1 and TAC
RT clones.";
RL DNA Res. 7:31-63(2000).
RN [2]
RP GENOME REANNOTATION.
RC STRAIN=cv. Columbia;
RX PubMed=27862469; DOI=10.1111/tpj.13415;
RA Cheng C.Y., Krishnakumar V., Chan A.P., Thibaud-Nissen F., Schobel S.,
RA Town C.D.;
RT "Araport11: a complete reannotation of the Arabidopsis thaliana reference
RT genome.";
RL Plant J. 89:789-804(2017).
RN [3]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC STRAIN=cv. Columbia;
RX PubMed=14593172; DOI=10.1126/science.1088305;
RA Yamada K., Lim J., Dale J.M., Chen H., Shinn P., Palm C.J., Southwick A.M.,
RA Wu H.C., Kim C.J., Nguyen M., Pham P.K., Cheuk R.F., Karlin-Newmann G.,
RA Liu S.X., Lam B., Sakano H., Wu T., Yu G., Miranda M., Quach H.L.,
RA Tripp M., Chang C.H., Lee J.M., Toriumi M.J., Chan M.M., Tang C.C.,
RA Onodera C.S., Deng J.M., Akiyama K., Ansari Y., Arakawa T., Banh J.,
RA Banno F., Bowser L., Brooks S.Y., Carninci P., Chao Q., Choy N., Enju A.,
RA Goldsmith A.D., Gurjal M., Hansen N.F., Hayashizaki Y., Johnson-Hopson C.,
RA Hsuan V.W., Iida K., Karnes M., Khan S., Koesema E., Ishida J., Jiang P.X.,
RA Jones T., Kawai J., Kamiya A., Meyers C., Nakajima M., Narusaka M.,
RA Seki M., Sakurai T., Satou M., Tamse R., Vaysberg M., Wallender E.K.,
RA Wong C., Yamamura Y., Yuan S., Shinozaki K., Davis R.W., Theologis A.,
RA Ecker J.R.;
RT "Empirical analysis of transcriptional activity in the Arabidopsis
RT genome.";
RL Science 302:842-846(2003).
RN [4]
RP NOMENCLATURE.
RX PubMed=18221561; DOI=10.1186/1471-2164-9-44;
RA Wang D., Guo Y., Wu C., Yang G., Li Y., Zheng C.;
RT "Genome-wide analysis of CCCH zinc finger family in Arabidopsis and rice.";
RL BMC Genomics 9:44-44(2008).
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DR EMBL; AB020755; BAA97332.1; -; Genomic_DNA.
DR EMBL; CP002688; AED97077.1; -; Genomic_DNA.
DR EMBL; AY054176; AAL06837.1; -; mRNA.
DR EMBL; AY062491; AAL32569.1; -; mRNA.
DR EMBL; AY103314; AAM65365.1; -; mRNA.
DR EMBL; BT002083; AAN72094.1; -; mRNA.
DR RefSeq; NP_200670.1; NM_125249.3.
DR AlphaFoldDB; Q9LUZ4; -.
DR SMR; Q9LUZ4; -.
DR BioGRID; 21220; 20.
DR IntAct; Q9LUZ4; 20.
DR STRING; 3702.AT5G58620.1; -.
DR iPTMnet; Q9LUZ4; -.
DR PaxDb; Q9LUZ4; -.
DR PRIDE; Q9LUZ4; -.
DR ProteomicsDB; 239197; -.
DR EnsemblPlants; AT5G58620.1; AT5G58620.1; AT5G58620.
DR GeneID; 835976; -.
DR Gramene; AT5G58620.1; AT5G58620.1; AT5G58620.
DR KEGG; ath:AT5G58620; -.
DR Araport; AT5G58620; -.
DR TAIR; locus:2178843; AT5G58620.
DR eggNOG; KOG1595; Eukaryota.
DR HOGENOM; CLU_015068_1_0_1; -.
DR InParanoid; Q9LUZ4; -.
DR OMA; GNMWQNQ; -.
DR OrthoDB; 905042at2759; -.
DR PhylomeDB; Q9LUZ4; -.
DR PRO; PR:Q9LUZ4; -.
DR Proteomes; UP000006548; Chromosome 5.
DR ExpressionAtlas; Q9LUZ4; baseline and differential.
DR Genevisible; Q9LUZ4; AT.
DR GO; GO:0010494; C:cytoplasmic stress granule; IDA:TAIR.
DR GO; GO:0000932; C:P-body; IDA:TAIR.
DR GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR GO; GO:0003700; F:DNA-binding transcription factor activity; ISS:TAIR.
DR GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR GO; GO:0003723; F:RNA binding; IDA:TAIR.
DR GO; GO:0006355; P:regulation of transcription, DNA-templated; TAS:TAIR.
DR GO; GO:0006412; P:translation; IMP:TAIR.
DR Gene3D; 1.25.40.20; -; 1.
DR InterPro; IPR002110; Ankyrin_rpt.
DR InterPro; IPR036770; Ankyrin_rpt-contain_sf.
DR InterPro; IPR045234; Unkempt-like.
DR InterPro; IPR000571; Znf_CCCH.
DR PANTHER; PTHR14493; PTHR14493; 1.
DR Pfam; PF12796; Ank_2; 1.
DR Pfam; PF00642; zf-CCCH; 1.
DR SMART; SM00248; ANK; 2.
DR SMART; SM00356; ZnF_C3H1; 2.
DR SUPFAM; SSF48403; SSF48403; 1.
DR PROSITE; PS50297; ANK_REP_REGION; 1.
DR PROSITE; PS50088; ANK_REPEAT; 1.
DR PROSITE; PS50103; ZF_C3H1; 2.
PE 2: Evidence at transcript level;
KW ANK repeat; DNA-binding; Metal-binding; Reference proteome; Repeat; Zinc;
KW Zinc-finger.
FT CHAIN 1..607
FT /note="Zinc finger CCCH domain-containing protein 66"
FT /id="PRO_0000372016"
FT REPEAT 57..87
FT /note="ANK 1"
FT REPEAT 92..124
FT /note="ANK 2"
FT ZN_FING 254..276
FT /note="C3H1-type 1"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00723"
FT ZN_FING 284..308
FT /note="C3H1-type 2"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00723"
FT REGION 161..193
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 342..363
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 177..193
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 607 AA; 66448 MW; C8788E2D554335E7 CRC64;
MGVDELSHLK FSLLLESSAC NDLSGFKSLV EEEGLESIDG SGLWYGRRLG SKKMGFEERT
PLMIAALFGS KEVVDYIIST GLVDVNRSCG SDGATALHCA VSGLSANSLE IVTLLLKGSA
NPDSCDAYGN KPGDVIFPCL SPVFSARMKV LERLLKGNDD LNEVNGQEES EPEVEVEVEV
SPPRGSERKE YPVDPTLPDI KNGVYGTDEF RMYAFKIKPC SRAYSHDWTE CPFVHPGENA
RRRDPRKYHY SCVPCPEFRK GSCSRGDTCE YAHGIFECWL HPAQYRTRLC KDETNCSRRV
CFFAHKPEEL RPLYPSTGSG VPSPRSSFSS CNSSTAFDMG PISPLPIGAT TTPPLSPNGV
SSPIGGGKTW MNWPNITPPA LQLPGSRLKS ALNAREIDFS EEMQSLTSPT TWNNTPMSSP
FSGKGMNRLA GGAMSPVNSL SDMFGTEDNT SGLQIRRSVI NPQLHSNSLS SSPVGANSLF
SMDSSAVLAS RAAEFAKQRS QSFIERNNGL NHHPAISSMT TTCLNDWGSL DGKLDWSVQG
DELQKLRKST SFRLRAGGME SRLPNEGTGL EEPDVSWVEP LVKEPQETRL APVWMEQSYM
ETEQTVA
