C3H67_ARATH
ID C3H67_ARATH Reviewed; 435 AA.
AC Q5RJC5; Q0WQB2; Q9FMJ7;
DT 26-APR-2005, integrated into UniProtKB/Swiss-Prot.
DT 26-APR-2005, sequence version 2.
DT 03-AUG-2022, entry version 109.
DE RecName: Full=Zinc finger CCCH domain-containing protein 67;
DE Short=AtC3H67;
DE AltName: Full=Zinc finger CCCH domain-containing protein ZFN-like 5;
GN OrderedLocusNames=At5g63260; ORFNames=MDC12.23;
OS Arabidopsis thaliana (Mouse-ear cress).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis.
OX NCBI_TaxID=3702;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. Columbia;
RX PubMed=9501997; DOI=10.1093/dnares/4.6.401;
RA Nakamura Y., Sato S., Kaneko T., Kotani H., Asamizu E., Miyajima N.,
RA Tabata S.;
RT "Structural analysis of Arabidopsis thaliana chromosome 5. III. Sequence
RT features of the regions of 1,191,918 bp covered by seventeen physically
RT assigned P1 clones.";
RL DNA Res. 4:401-414(1997).
RN [2]
RP GENOME REANNOTATION.
RC STRAIN=cv. Columbia;
RX PubMed=27862469; DOI=10.1111/tpj.13415;
RA Cheng C.Y., Krishnakumar V., Chan A.P., Thibaud-Nissen F., Schobel S.,
RA Town C.D.;
RT "Araport11: a complete reannotation of the Arabidopsis thaliana reference
RT genome.";
RL Plant J. 89:789-804(2017).
RN [3]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC STRAIN=cv. Columbia;
RA Shinn P., Chen H., Cheuk R.F., Kim C.J., Ecker J.R.;
RT "Arabidopsis cDNA clones.";
RL Submitted (DEC-2004) to the EMBL/GenBank/DDBJ databases.
RN [4]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC STRAIN=cv. Columbia;
RA Totoki Y., Seki M., Ishida J., Nakajima M., Enju A., Kamiya A.,
RA Narusaka M., Shin-i T., Nakagawa M., Sakamoto N., Oishi K., Kohara Y.,
RA Kobayashi M., Toyoda A., Sakaki Y., Sakurai T., Iida K., Akiyama K.,
RA Satou M., Toyoda T., Konagaya A., Carninci P., Kawai J., Hayashizaki Y.,
RA Shinozaki K.;
RT "Large-scale analysis of RIKEN Arabidopsis full-length (RAFL) cDNAs.";
RL Submitted (JUL-2006) to the EMBL/GenBank/DDBJ databases.
RN [5]
RP NOMENCLATURE.
RX PubMed=18221561; DOI=10.1186/1471-2164-9-44;
RA Wang D., Guo Y., Wu C., Yang G., Li Y., Zheng C.;
RT "Genome-wide analysis of CCCH zinc finger family in Arabidopsis and rice.";
RL BMC Genomics 9:44-44(2008).
CC -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000250}.
CC -!- ALTERNATIVE PRODUCTS:
CC Event=Alternative splicing; Named isoforms=1;
CC Comment=A number of isoforms are produced. According to EST
CC sequences.;
CC Name=1;
CC IsoId=Q5RJC5-1; Sequence=Displayed;
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; AB008265; BAB10568.1; -; Genomic_DNA.
DR EMBL; CP002688; AED97724.1; -; Genomic_DNA.
DR EMBL; BT020223; AAV66094.1; -; mRNA.
DR EMBL; BT020443; AAW30022.1; -; mRNA.
DR EMBL; AK228790; BAF00687.1; -; mRNA.
DR RefSeq; NP_201131.1; NM_125721.3. [Q5RJC5-1]
DR AlphaFoldDB; Q5RJC5; -.
DR STRING; 3702.AT5G63260.2; -.
DR iPTMnet; Q5RJC5; -.
DR PaxDb; Q5RJC5; -.
DR PRIDE; Q5RJC5; -.
DR ProteomicsDB; 240524; -. [Q5RJC5-1]
DR EnsemblPlants; AT5G63260.1; AT5G63260.1; AT5G63260. [Q5RJC5-1]
DR GeneID; 836446; -.
DR Gramene; AT5G63260.1; AT5G63260.1; AT5G63260. [Q5RJC5-1]
DR KEGG; ath:AT5G63260; -.
DR Araport; AT5G63260; -.
DR eggNOG; KOG1677; Eukaryota.
DR HOGENOM; CLU_033292_3_1_1; -.
DR InParanoid; Q5RJC5; -.
DR PhylomeDB; Q5RJC5; -.
DR PRO; PR:Q5RJC5; -.
DR Proteomes; UP000006548; Chromosome 5.
DR ExpressionAtlas; Q5RJC5; baseline and differential.
DR Genevisible; Q5RJC5; AT.
DR GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR GO; GO:0003729; F:mRNA binding; IBA:GO_Central.
DR InterPro; IPR000571; Znf_CCCH.
DR InterPro; IPR036855; Znf_CCCH_sf.
DR Pfam; PF00642; zf-CCCH; 4.
DR SMART; SM00356; ZnF_C3H1; 5.
DR SUPFAM; SSF90229; SSF90229; 5.
DR PROSITE; PS50103; ZF_C3H1; 5.
PE 2: Evidence at transcript level;
KW Alternative splicing; DNA-binding; Metal-binding; Nucleus;
KW Reference proteome; Repeat; Zinc; Zinc-finger.
FT CHAIN 1..435
FT /note="Zinc finger CCCH domain-containing protein 67"
FT /id="PRO_0000213919"
FT ZN_FING 101..129
FT /note="C3H1-type 1"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00723"
FT ZN_FING 148..176
FT /note="C3H1-type 2"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00723"
FT ZN_FING 194..222
FT /note="C3H1-type 3"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00723"
FT ZN_FING 334..362
FT /note="C3H1-type 4"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00723"
FT ZN_FING 380..408
FT /note="C3H1-type 5"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00723"
FT REGION 1..91
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 235..274
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 412..435
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1..28
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 36..53
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 235..264
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT CONFLICT 101
FT /note="R -> K (in Ref. 3; AAV66094/AAW30022)"
FT /evidence="ECO:0000305"
SQ SEQUENCE 435 AA; 48607 MW; 8BACBB780A03C6F2 CRC64;
MSKPEETSDP NPTGPDPSRS SSDEVTVTVA DRAPSDLNHV SEELSDQLRN VGLDDSAKEL
SVPISVPQGN VETDSRALFG SDQKEEEEGS EKRMMMVYPV RPDSEDCSFY MRTGSCKYGS
SCKFNHPVRR KLQIGRERVR ERDEDVENPK LMECKYYFRT GGCKYGESCR FSHMKEHNSP
ASVPELNFLG LPIRPGEKEC PFYMRNGSCK FGSDCKFNHP DPTAIGGVDS PLYRGNNGGS
FSPKAPSQAS STSWSSTRHM NGTGTAPFIP SMFPHSRGVT PQASDWNGYQ ASSAYPPERS
PLAPSSYQVN NSLAETSSFS QYQHQMSVEE FPERPDQPEC TYYLKTGDCK FKYKCKYHHP
KNRLPKQAAF SFNDKGLPLR PDQSMCTHYS RYGICKFGPA CRFDHSIPPT FSPSSSQTVE
ARQVGANGNE DDSWH
