TSN13_BOVIN
ID TSN13_BOVIN Reviewed; 204 AA.
AC Q3ZBV0;
DT 01-MAY-2007, integrated into UniProtKB/Swiss-Prot.
DT 27-SEP-2005, sequence version 1.
DT 03-AUG-2022, entry version 83.
DE RecName: Full=Tetraspanin-13;
DE Short=Tspan-13;
GN Name=TSPAN13;
OS Bos taurus (Bovine).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Laurasiatheria; Artiodactyla; Ruminantia; Pecora; Bovidae;
OC Bovinae; Bos.
OX NCBI_TaxID=9913;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC STRAIN=Crossbred X Angus; TISSUE=Ileum;
RG NIH - Mammalian Gene Collection (MGC) project;
RL Submitted (AUG-2005) to the EMBL/GenBank/DDBJ databases.
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000305}; Multi-pass membrane
CC protein {ECO:0000305}.
CC -!- SIMILARITY: Belongs to the tetraspanin (TM4SF) family. {ECO:0000305}.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; BC103095; AAI03096.1; -; mRNA.
DR RefSeq; NP_001030439.1; NM_001035362.1.
DR AlphaFoldDB; Q3ZBV0; -.
DR SMR; Q3ZBV0; -.
DR STRING; 9913.ENSBTAP00000017010; -.
DR PaxDb; Q3ZBV0; -.
DR PRIDE; Q3ZBV0; -.
DR Ensembl; ENSBTAT00000017010; ENSBTAP00000017010; ENSBTAG00000012805.
DR GeneID; 526460; -.
DR KEGG; bta:526460; -.
DR CTD; 27075; -.
DR VEuPathDB; HostDB:ENSBTAG00000012805; -.
DR VGNC; VGNC:36428; TSPAN13.
DR eggNOG; KOG3882; Eukaryota.
DR GeneTree; ENSGT00940000157010; -.
DR HOGENOM; CLU_088363_0_0_1; -.
DR InParanoid; Q3ZBV0; -.
DR OMA; CPPCAPI; -.
DR OrthoDB; 1203231at2759; -.
DR TreeFam; TF323367; -.
DR Proteomes; UP000009136; Chromosome 4.
DR Bgee; ENSBTAG00000012805; Expressed in occipital lobe and 104 other tissues.
DR GO; GO:0005887; C:integral component of plasma membrane; IBA:GO_Central.
DR GO; GO:0005246; F:calcium channel regulator activity; IEA:Ensembl.
DR GO; GO:1903169; P:regulation of calcium ion transmembrane transport; IEA:Ensembl.
DR InterPro; IPR018499; Tetraspanin/Peripherin.
DR InterPro; IPR000301; Tetraspanin_animals.
DR PANTHER; PTHR19282; PTHR19282; 1.
DR Pfam; PF00335; Tetraspanin; 1.
DR PIRSF; PIRSF002419; Tetraspanin; 1.
PE 2: Evidence at transcript level;
KW Glycoprotein; Membrane; Phosphoprotein; Reference proteome; Transmembrane;
KW Transmembrane helix.
FT CHAIN 1..204
FT /note="Tetraspanin-13"
FT /id="PRO_0000284965"
FT TOPO_DOM 1..19
FT /note="Cytoplasmic"
FT /evidence="ECO:0000255"
FT TRANSMEM 20..40
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TOPO_DOM 41..44
FT /note="Extracellular"
FT /evidence="ECO:0000255"
FT TRANSMEM 45..65
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TOPO_DOM 66..72
FT /note="Cytoplasmic"
FT /evidence="ECO:0000255"
FT TRANSMEM 73..93
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TOPO_DOM 94..167
FT /note="Extracellular"
FT /evidence="ECO:0000255"
FT TRANSMEM 168..188
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TOPO_DOM 189..204
FT /note="Cytoplasmic"
FT /evidence="ECO:0000255"
FT MOD_RES 143
FT /note="Phosphoserine"
FT /evidence="ECO:0000250|UniProtKB:Q9D8C2"
FT CARBOHYD 113
FT /note="N-linked (GlcNAc...) asparagine"
FT /evidence="ECO:0000255"
FT CARBOHYD 137
FT /note="N-linked (GlcNAc...) asparagine"
FT /evidence="ECO:0000255"
SQ SEQUENCE 204 AA; 22219 MW; ADC2F7293BE4A48F CRC64;
MVCGGFACSK NCLCALNLLY TLVSLLLIGI AAWGIGFGLI SSLRVVGVVI AVGIFLFLIA
LVGLIGAVKH HQVLLFFYMI ILLLVFIVQF SVSCACLALN QEQQAQLLEV GWNNTASARD
DIQRNLNCCG FRSFNPNDTC LASCVKSSHP CSPCAPIIGR YAGEVLRFVG GIGLFFSFTE
ILGVWLTYRY RNQKDPRANP SAFL