ID   TSN31_DANRE             Reviewed;         212 AA.
AC   Q7ZUB3; Q6TGU5;
DT   26-APR-2005, integrated into UniProtKB/Swiss-Prot.
DT   26-APR-2005, sequence version 2.
DT   03-AUG-2022, entry version 98.
DE   RecName: Full=Tetraspanin-31;
DE            Short=Tspan-31;
DE   AltName: Full=Sarcoma-amplified sequence homolog;
GN   Name=tspan31; Synonyms=sas; ORFNames=zgc:56710;
OS   Danio rerio (Zebrafish) (Brachydanio rerio).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC   Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes;
OC   Danionidae; Danioninae; Danio.
OX   NCBI_TaxID=7955;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC   TISSUE=Kidney marrow;
RX   PubMed=15520368; DOI=10.1073/pnas.0407241101;
RA   Song H.-D., Sun X.-J., Deng M., Zhang G.-W., Zhou Y., Wu X.-Y., Sheng Y.,
RA   Chen Y., Ruan Z., Jiang C.-L., Fan H.-Y., Zon L.I., Kanki J.P., Liu T.X.,
RA   Look A.T., Chen Z.;
RT   "Hematopoietic gene expression profile in zebrafish kidney marrow.";
RL   Proc. Natl. Acad. Sci. U.S.A. 101:16240-16245(2004).
RN   [2]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RG   NIH - Zebrafish Gene Collection (ZGC) project;
RL   Submitted (MAR-2003) to the EMBL/GenBank/DDBJ databases.
CC   -!- SUBCELLULAR LOCATION: Membrane {ECO:0000250}; Multi-pass membrane
CC       protein {ECO:0000250}.
CC   -!- SIMILARITY: Belongs to the tetraspanin (TM4SF) family. {ECO:0000305}.
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DR   EMBL; AY398411; AAQ97844.1; -; mRNA.
DR   EMBL; BC049345; AAH49345.1; -; mRNA.
DR   RefSeq; NP_956575.1; NM_200281.1.
DR   AlphaFoldDB; Q7ZUB3; -.
DR   SMR; Q7ZUB3; -.
DR   STRING; 7955.ENSDARP00000103343; -.
DR   PaxDb; Q7ZUB3; -.
DR   Ensembl; ENSDART00000113179; ENSDARP00000103343; ENSDARG00000074554.
DR   GeneID; 393251; -.
DR   KEGG; dre:393251; -.
DR   CTD; 6302; -.
DR   ZFIN; ZDB-GENE-040426-1123; tspan31.
DR   eggNOG; KOG3882; Eukaryota.
DR   GeneTree; ENSGT00940000160351; -.
DR   HOGENOM; CLU_088363_0_0_1; -.
DR   InParanoid; Q7ZUB3; -.
DR   OMA; WGILENN; -.
DR   OrthoDB; 1203231at2759; -.
DR   PhylomeDB; Q7ZUB3; -.
DR   TreeFam; TF323367; -.
DR   PRO; PR:Q7ZUB3; -.
DR   Proteomes; UP000000437; Genome assembly.
DR   Proteomes; UP000814640; Chromosome 23.
DR   Bgee; ENSDARG00000074554; Expressed in mature ovarian follicle and 29 other tissues.
DR   GO; GO:0005887; C:integral component of plasma membrane; IBA:GO_Central.
DR   InterPro; IPR018499; Tetraspanin/Peripherin.
DR   InterPro; IPR000301; Tetraspanin_animals.
DR   PANTHER; PTHR19282; PTHR19282; 1.
DR   Pfam; PF00335; Tetraspanin; 1.
DR   PIRSF; PIRSF002419; Tetraspanin; 1.
PE   2: Evidence at transcript level;
KW   Glycoprotein; Membrane; Reference proteome; Transmembrane;
KW   Transmembrane helix.
FT   CHAIN           1..212
FT                   /note="Tetraspanin-31"
FT                   /id="PRO_0000219275"
FT   TOPO_DOM        1..12
FT                   /note="Cytoplasmic"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        13..33
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TOPO_DOM        34..44
FT                   /note="Extracellular"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        45..65
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TOPO_DOM        66..72
FT                   /note="Cytoplasmic"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        73..93
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TOPO_DOM        94..175
FT                   /note="Extracellular"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        176..196
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TOPO_DOM        197..212
FT                   /note="Cytoplasmic"
FT                   /evidence="ECO:0000255"
FT   CARBOHYD        117
FT                   /note="N-linked (GlcNAc...) asparagine"
FT                   /evidence="ECO:0000255"
FT   CARBOHYD        134
FT                   /note="N-linked (GlcNAc...) asparagine"
FT                   /evidence="ECO:0000255"
FT   CONFLICT        164
FT                   /note="L -> P (in Ref. 2; AAH49345)"
FT                   /evidence="ECO:0000305"
FT   CONFLICT        169
FT                   /note="H -> Y (in Ref. 2; AAH49345)"
FT                   /evidence="ECO:0000305"
SQ   SEQUENCE   212 AA;  23270 MW;  0F45ED7D7A407371 CRC64;
     MVCGGFTCSK NALCSLNVVY MLVGLLLIVV AAWGKGFGIV SSIHIIGGVI AVGFFLQLIA
     IVGLIGAVHH HQVMLFFYMV ILFVVFLFQF GVSCSCLAMN QGQQEKLLES SWKIMSNDTR
     ISLEKKLDCC GLFNSTNLQA DIMSDLHLCT SPCTQKKECV TCGLKMLQHS SEALKILGGV
     GLFFSFTEIL GVWLAMRYRN QKDPRANPSA FL