TSN7_PONPY
ID TSN7_PONPY Reviewed; 244 AA.
AC Q7YQK9;
DT 10-MAY-2004, integrated into UniProtKB/Swiss-Prot.
DT 01-OCT-2003, sequence version 1.
DT 25-MAY-2022, entry version 58.
DE RecName: Full=Tetraspanin-7;
DE Short=Tspan-7;
DE AltName: Full=Transmembrane 4 superfamily member 2;
DE AltName: CD_antigen=CD231;
GN Name=TSPAN7; Synonyms=TM4SF2;
OS Pongo pygmaeus (Bornean orangutan).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae;
OC Pongo.
OX NCBI_TaxID=9600;
RN [1]
RP NUCLEOTIDE SEQUENCE [MRNA].
RX PubMed=12777533; DOI=10.1093/molbev/msg134;
RA Kitano T., Schwarz C., Nickel B., Paeaebo S.;
RT "Gene diversity patterns at 10 X-chromosomal loci in humans and
RT chimpanzees.";
RL Mol. Biol. Evol. 20:1281-1289(2003).
CC -!- FUNCTION: May be involved in cell proliferation and cell motility.
CC -!- SUBCELLULAR LOCATION: Membrane; Multi-pass membrane protein.
CC -!- SIMILARITY: Belongs to the tetraspanin (TM4SF) family. {ECO:0000305}.
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DR EMBL; AB102667; BAC81136.1; -; mRNA.
DR AlphaFoldDB; Q7YQK9; -.
DR SMR; Q7YQK9; -.
DR GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR Gene3D; 1.10.1450.10; -; 1.
DR InterPro; IPR018499; Tetraspanin/Peripherin.
DR InterPro; IPR000301; Tetraspanin_animals.
DR InterPro; IPR018503; Tetraspanin_CS.
DR InterPro; IPR008952; Tetraspanin_EC2_sf.
DR PANTHER; PTHR19282; PTHR19282; 1.
DR Pfam; PF00335; Tetraspanin; 1.
DR PIRSF; PIRSF002419; Tetraspanin; 1.
DR SUPFAM; SSF48652; SSF48652; 1.
DR PROSITE; PS00421; TM4_1; 1.
PE 2: Evidence at transcript level;
KW Glycoprotein; Membrane; Transmembrane; Transmembrane helix.
FT CHAIN 1..244
FT /note="Tetraspanin-7"
FT /id="PRO_0000219251"
FT TOPO_DOM 1..11
FT /note="Cytoplasmic"
FT /evidence="ECO:0000255"
FT TRANSMEM 12..35
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TOPO_DOM 36..51
FT /note="Extracellular"
FT /evidence="ECO:0000255"
FT TRANSMEM 52..70
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TOPO_DOM 71..81
FT /note="Cytoplasmic"
FT /evidence="ECO:0000255"
FT TRANSMEM 82..107
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TOPO_DOM 108..208
FT /note="Extracellular"
FT /evidence="ECO:0000255"
FT TRANSMEM 209..229
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TOPO_DOM 230..244
FT /note="Cytoplasmic"
FT /evidence="ECO:0000255"
FT CARBOHYD 49
FT /note="N-linked (GlcNAc...) asparagine"
FT /evidence="ECO:0000255"
FT CARBOHYD 150
FT /note="N-linked (GlcNAc...) asparagine"
FT /evidence="ECO:0000255"
FT CARBOHYD 153
FT /note="N-linked (GlcNAc...) asparagine"
FT /evidence="ECO:0000255"
FT CARBOHYD 172
FT /note="N-linked (GlcNAc...) asparagine"
FT /evidence="ECO:0000255"
FT CARBOHYD 183
FT /note="N-linked (GlcNAc...) asparagine"
FT /evidence="ECO:0000255"
SQ SEQUENCE 244 AA; 26945 MW; 656EA949EE19050B CRC64;
METKPVITCL KTLLIIYSFV FWITGVILLA VGVWGKLTLG TYISLIAENS TNAPYVLIGT
GTTIVVFGLF GCFATCRGSP WMLKLYAMFL SLVFLAELVA GISGFVFRHE IKDTFLRTYT
DAMQTYDGKD DRSQAVDHVQ RSLSCCGVQN YTNWSTSPYF LEHGIPPSCC MNETDCNPQD
LHNLTVAATK VNQKGCYDLV TSFMETNMGI IAGVAFGIAF SQLIGMLLAC CLSRFITANQ
YEMV
