ID   TSN9_PIG                Reviewed;         239 AA.
AC   Q06AA5;
DT   26-MAY-2009, integrated into UniProtKB/Swiss-Prot.
DT   31-OCT-2006, sequence version 1.
DT   03-AUG-2022, entry version 76.
DE   RecName: Full=Tetraspanin-9;
DE            Short=Tspan-9;
GN   Name=TSPAN9;
OS   Sus scrofa (Pig).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC   Eutheria; Laurasiatheria; Artiodactyla; Suina; Suidae; Sus.
OX   NCBI_TaxID=9823;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RA   Liu G.Y.;
RL   Submitted (AUG-2006) to the EMBL/GenBank/DDBJ databases.
CC   -!- SUBUNIT: Found in a complex with GP6. {ECO:0000250}.
CC   -!- SUBCELLULAR LOCATION: Membrane {ECO:0000250}; Multi-pass membrane
CC       protein {ECO:0000250}. Note=Colocalizes with GP6 in tetraspanin
CC       microdomains on the platelet surface. {ECO:0000250}.
CC   -!- PTM: Glycosylated. {ECO:0000250}.
CC   -!- SIMILARITY: Belongs to the tetraspanin (TM4SF) family. {ECO:0000305}.
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DR   EMBL; DQ972959; ABI96195.1; -; mRNA.
DR   RefSeq; NP_001070694.1; NM_001077226.1.
DR   RefSeq; XP_005664127.1; XM_005664070.2.
DR   RefSeq; XP_013853281.1; XM_013997827.1.
DR   AlphaFoldDB; Q06AA5; -.
DR   SMR; Q06AA5; -.
DR   STRING; 9823.ENSSSCP00000000782; -.
DR   PaxDb; Q06AA5; -.
DR   PeptideAtlas; Q06AA5; -.
DR   Ensembl; ENSSSCT00000000798; ENSSSCP00000000782; ENSSSCG00000000735.
DR   Ensembl; ENSSSCT00015060317; ENSSSCP00015024248; ENSSSCG00015045122.
DR   Ensembl; ENSSSCT00025008655; ENSSSCP00025003401; ENSSSCG00025006547.
DR   Ensembl; ENSSSCT00030007670; ENSSSCP00030003407; ENSSSCG00030005625.
DR   Ensembl; ENSSSCT00035015922; ENSSSCP00035005487; ENSSSCG00035012623.
DR   Ensembl; ENSSSCT00040030886; ENSSSCP00040012859; ENSSSCG00040023030.
DR   Ensembl; ENSSSCT00045047266; ENSSSCP00045032836; ENSSSCG00045027673.
DR   Ensembl; ENSSSCT00050098528; ENSSSCP00050042549; ENSSSCG00050072191.
DR   Ensembl; ENSSSCT00055028000; ENSSSCP00055022306; ENSSSCG00055014115.
DR   Ensembl; ENSSSCT00060095493; ENSSSCP00060041309; ENSSSCG00060069845.
DR   Ensembl; ENSSSCT00065033603; ENSSSCP00065013910; ENSSSCG00065025113.
DR   GeneID; 768114; -.
DR   KEGG; ssc:768114; -.
DR   CTD; 10867; -.
DR   VGNC; VGNC:94516; TSPAN9.
DR   eggNOG; KOG3882; Eukaryota.
DR   GeneTree; ENSGT00940000158225; -.
DR   HOGENOM; CLU_055524_4_3_1; -.
DR   InParanoid; Q06AA5; -.
DR   OrthoDB; 1224210at2759; -.
DR   TreeFam; TF352892; -.
DR   Proteomes; UP000008227; Chromosome 5.
DR   Proteomes; UP000314985; Unplaced.
DR   Bgee; ENSSSCG00000000735; Expressed in cerebellum and 43 other tissues.
DR   ExpressionAtlas; Q06AA5; baseline and differential.
DR   Genevisible; Q06AA5; SS.
DR   GO; GO:0005887; C:integral component of plasma membrane; IBA:GO_Central.
DR   Gene3D; 1.10.1450.10; -; 1.
DR   InterPro; IPR018499; Tetraspanin/Peripherin.
DR   InterPro; IPR000301; Tetraspanin_animals.
DR   InterPro; IPR018503; Tetraspanin_CS.
DR   InterPro; IPR008952; Tetraspanin_EC2_sf.
DR   PANTHER; PTHR19282; PTHR19282; 1.
DR   Pfam; PF00335; Tetraspanin; 1.
DR   PIRSF; PIRSF002419; Tetraspanin; 1.
DR   SUPFAM; SSF48652; SSF48652; 1.
DR   PROSITE; PS00421; TM4_1; 1.
PE   2: Evidence at transcript level;
KW   Glycoprotein; Membrane; Reference proteome; Transmembrane;
KW   Transmembrane helix.
FT   CHAIN           1..239
FT                   /note="Tetraspanin-9"
FT                   /id="PRO_0000375881"
FT   TOPO_DOM        1..13
FT                   /note="Cytoplasmic"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        14..34
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TOPO_DOM        35..55
FT                   /note="Extracellular"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        56..76
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TOPO_DOM        77..85
FT                   /note="Cytoplasmic"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        86..106
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TOPO_DOM        107..203
FT                   /note="Extracellular"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        204..224
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TOPO_DOM        225..239
FT                   /note="Cytoplasmic"
FT                   /evidence="ECO:0000255"
FT   CARBOHYD        180
FT                   /note="N-linked (GlcNAc...) asparagine"
FT                   /evidence="ECO:0000255"
SQ   SEQUENCE   239 AA;  26781 MW;  EA03E457BEEE539D CRC64;
     MARGCLCCLK YMMFLFNLIF WLCGCGLLGV GIWLSVSQGN FATFSPSFPS LSAANLVIAI
     GTIVMVTGFL GCLGAIKENR CLLLSFFIVL LIILLAELIL IILFFVYMDK VNENARKDLK
     EGLLLYNSEN NVGLKNAWNI IQAEMHCCGV TDYTDWYPVL GENTVPDRCC MENSQGCGRN
     STTPLWKTGC YEKVKMWFDD NKHVLGTVGM CILIMQILGM AFSMTLFQHI HRTGKKYDA