ID   TSN9_SHEEP              Reviewed;         239 AA.
AC   B3VSC2;
DT   26-MAY-2009, integrated into UniProtKB/Swiss-Prot.
DT   02-SEP-2008, sequence version 1.
DT   03-AUG-2022, entry version 41.
DE   RecName: Full=Tetraspanin-9;
DE            Short=Tspan-9;
DE   AltName: Full=Tetraspan NET-5;
GN   Name=TSPAN9; Synonyms=NET5;
OS   Ovis aries (Sheep).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC   Eutheria; Laurasiatheria; Artiodactyla; Ruminantia; Pecora; Bovidae;
OC   Caprinae; Ovis.
OX   NCBI_TaxID=9940;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [MRNA].
RA   Liu L., Yu Y., Deng W.;
RT   "Molecular cloning and sequence analysis of TNE5 from Black-boned sheep
RT   (Ovis aries).";
RL   Submitted (JUN-2008) to the EMBL/GenBank/DDBJ databases.
CC   -!- SUBUNIT: Found in a complex with GP6. {ECO:0000250}.
CC   -!- SUBCELLULAR LOCATION: Membrane {ECO:0000250}; Multi-pass membrane
CC       protein {ECO:0000250}. Note=Colocalizes with GP6 in tetraspanin
CC       microdomains on the platelet surface. {ECO:0000250}.
CC   -!- PTM: Glycosylated. {ECO:0000250}.
CC   -!- SIMILARITY: Belongs to the tetraspanin (TM4SF) family. {ECO:0000305}.
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DR   EMBL; EU797610; ACF16976.1; -; mRNA.
DR   RefSeq; NP_001127777.1; NM_001134305.1.
DR   AlphaFoldDB; B3VSC2; -.
DR   SMR; B3VSC2; -.
DR   STRING; 9940.ENSOARP00000011493; -.
DR   Ensembl; ENSOART00020017263; ENSOARP00020014250; ENSOARG00020011321.
DR   GeneID; 100180629; -.
DR   KEGG; oas:100180629; -.
DR   CTD; 10867; -.
DR   eggNOG; KOG3882; Eukaryota.
DR   OrthoDB; 1224210at2759; -.
DR   Proteomes; UP000002356; Unplaced.
DR   GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR   Gene3D; 1.10.1450.10; -; 1.
DR   InterPro; IPR018499; Tetraspanin/Peripherin.
DR   InterPro; IPR000301; Tetraspanin_animals.
DR   InterPro; IPR018503; Tetraspanin_CS.
DR   InterPro; IPR008952; Tetraspanin_EC2_sf.
DR   PANTHER; PTHR19282; PTHR19282; 1.
DR   Pfam; PF00335; Tetraspanin; 1.
DR   PIRSF; PIRSF002419; Tetraspanin; 1.
DR   SUPFAM; SSF48652; SSF48652; 1.
DR   PROSITE; PS00421; TM4_1; 1.
PE   2: Evidence at transcript level;
KW   Glycoprotein; Membrane; Reference proteome; Transmembrane;
KW   Transmembrane helix.
FT   CHAIN           1..239
FT                   /note="Tetraspanin-9"
FT                   /id="PRO_0000375882"
FT   TRANSMEM        14..34
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        56..76
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        86..106
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        204..224
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   CARBOHYD        180
FT                   /note="N-linked (GlcNAc...) asparagine"
FT                   /evidence="ECO:0000255"
FT   CARBOHYD        181
FT                   /note="N-linked (GlcNAc...) asparagine"
FT                   /evidence="ECO:0000255"
SQ   SEQUENCE   239 AA;  26714 MW;  6BE4552CF114874C CRC64;
     MARGCLCCLK YAMFLFNLIF WLCGCGLLGV GIWLSVSQGN FATFSPSFPS LSAANLVIAI
     GTIVMVTGFL GCLGAIKENR CLLLSFFIVL LIILLAELIL IILFFVYMDK VNENAKKDLK
     EGLLLYNSEN NVGLKNAWNI IQAEMHCCGV TDYRDWFLVL GENTVPDRCC MENSQGCGQN
     NTTLLWRTGC YEKVKQWFAD NKHVLGTVGM CLLITQILGM AFSMTLFQHI HRTGKKYDA