ID   TSN9_XENLA              Reviewed;         239 AA.
AC   Q6DCQ3;
DT   26-MAY-2009, integrated into UniProtKB/Swiss-Prot.
DT   16-AUG-2004, sequence version 1.
DT   03-AUG-2022, entry version 64.
DE   RecName: Full=Tetraspanin-9;
DE            Short=Tspan-9;
GN   Name=tspan9;
OS   Xenopus laevis (African clawed frog).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Amphibia;
OC   Batrachia; Anura; Pipoidea; Pipidae; Xenopodinae; Xenopus; Xenopus.
OX   NCBI_TaxID=8355;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC   TISSUE=Embryo;
RG   NIH - Xenopus Gene Collection (XGC) project;
RL   Submitted (JUL-2004) to the EMBL/GenBank/DDBJ databases.
CC   -!- SUBCELLULAR LOCATION: Membrane {ECO:0000250}; Multi-pass membrane
CC       protein {ECO:0000250}.
CC   -!- SIMILARITY: Belongs to the tetraspanin (TM4SF) family. {ECO:0000305}.
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DR   EMBL; BC077949; AAH77949.1; -; mRNA.
DR   RefSeq; NP_001087054.1; NM_001093585.1.
DR   RefSeq; XP_018109788.1; XM_018254299.1.
DR   AlphaFoldDB; Q6DCQ3; -.
DR   SMR; Q6DCQ3; -.
DR   DNASU; 446889; -.
DR   GeneID; 446889; -.
DR   KEGG; xla:446889; -.
DR   CTD; 446889; -.
DR   Xenbase; XB-GENE-956627; tspan9.S.
DR   OMA; DIQSWSG; -.
DR   OrthoDB; 1224210at2759; -.
DR   Proteomes; UP000186698; Chromosome 3S.
DR   Bgee; 446889; Expressed in internal ear and 19 other tissues.
DR   GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR   Gene3D; 1.10.1450.10; -; 1.
DR   InterPro; IPR018499; Tetraspanin/Peripherin.
DR   InterPro; IPR000301; Tetraspanin_animals.
DR   InterPro; IPR018503; Tetraspanin_CS.
DR   InterPro; IPR008952; Tetraspanin_EC2_sf.
DR   PANTHER; PTHR19282; PTHR19282; 1.
DR   Pfam; PF00335; Tetraspanin; 1.
DR   PIRSF; PIRSF002419; Tetraspanin; 1.
DR   SUPFAM; SSF48652; SSF48652; 1.
DR   PROSITE; PS00421; TM4_1; 1.
PE   2: Evidence at transcript level;
KW   Glycoprotein; Membrane; Reference proteome; Transmembrane;
KW   Transmembrane helix.
FT   CHAIN           1..239
FT                   /note="Tetraspanin-9"
FT                   /id="PRO_0000375885"
FT   TOPO_DOM        1..13
FT                   /note="Cytoplasmic"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        14..34
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TOPO_DOM        35..55
FT                   /note="Extracellular"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        56..76
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TOPO_DOM        77..85
FT                   /note="Cytoplasmic"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        86..106
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TOPO_DOM        107..203
FT                   /note="Extracellular"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        204..224
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TOPO_DOM        225..239
FT                   /note="Cytoplasmic"
FT                   /evidence="ECO:0000255"
FT   CARBOHYD        180
FT                   /note="N-linked (GlcNAc...) asparagine"
FT                   /evidence="ECO:0000255"
SQ   SEQUENCE   239 AA;  26783 MW;  D2D9B2DC6EDC9931 CRC64;
     MARGCLCCLK YMMFLFNLIF WLCGCGLLGV GIWLSVSQGN FATFSPSFPS LSAANLVIVI
     GTVVMVTGFL GCLGAIKENK CLLLSFFIIL LIILLTELIL LILFFVYMDK VNENAKQDLK
     DGLLLYNSEN NVGLKNAWNI IQAEMHCCGV TDYTDWYPVL GENTVPDRCC MENSQDCGHN
     STSLVWKTGC YEKVKMWFDD NKHVLGTIGM CILIIQILGM AFSMTLFQQI HRTGKKYDA