TSN9_XENTR
ID TSN9_XENTR Reviewed; 239 AA.
AC B0BM39;
DT 26-MAY-2009, integrated into UniProtKB/Swiss-Prot.
DT 26-FEB-2008, sequence version 1.
DT 03-AUG-2022, entry version 72.
DE RecName: Full=Tetraspanin-9;
DE Short=Tspan-9;
GN Name=tspan9;
OS Xenopus tropicalis (Western clawed frog) (Silurana tropicalis).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Amphibia;
OC Batrachia; Anura; Pipoidea; Pipidae; Xenopodinae; Xenopus; Silurana.
OX NCBI_TaxID=8364;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC TISSUE=Testis;
RG NIH - Xenopus Gene Collection (XGC) project;
RL Submitted (JAN-2008) to the EMBL/GenBank/DDBJ databases.
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000250}; Multi-pass membrane
CC protein {ECO:0000250}.
CC -!- SIMILARITY: Belongs to the tetraspanin (TM4SF) family. {ECO:0000305}.
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DR EMBL; BC158275; AAI58276.1; -; mRNA.
DR RefSeq; NP_001120002.1; NM_001126530.1.
DR RefSeq; XP_012813990.1; XM_012958536.2.
DR RefSeq; XP_012813991.1; XM_012958537.2.
DR RefSeq; XP_017947421.1; XM_018091932.1.
DR AlphaFoldDB; B0BM39; -.
DR SMR; B0BM39; -.
DR STRING; 8364.ENSXETP00000063035; -.
DR PaxDb; B0BM39; -.
DR Ensembl; ENSXETT00000065869; ENSXETP00000063035; ENSXETG00000016985.
DR GeneID; 100144960; -.
DR KEGG; xtr:100144960; -.
DR CTD; 10867; -.
DR Xenbase; XB-GENE-956624; tspan9.
DR eggNOG; KOG3882; Eukaryota.
DR HOGENOM; CLU_055524_4_3_1; -.
DR InParanoid; B0BM39; -.
DR OrthoDB; 1224210at2759; -.
DR TreeFam; TF352892; -.
DR Proteomes; UP000008143; Chromosome 3.
DR Proteomes; UP000790000; Unplaced.
DR Bgee; ENSXETG00000016985; Expressed in heart and 14 other tissues.
DR GO; GO:0005887; C:integral component of plasma membrane; IBA:GO_Central.
DR Gene3D; 1.10.1450.10; -; 1.
DR InterPro; IPR018499; Tetraspanin/Peripherin.
DR InterPro; IPR000301; Tetraspanin_animals.
DR InterPro; IPR018503; Tetraspanin_CS.
DR InterPro; IPR008952; Tetraspanin_EC2_sf.
DR PANTHER; PTHR19282; PTHR19282; 1.
DR Pfam; PF00335; Tetraspanin; 1.
DR PIRSF; PIRSF002419; Tetraspanin; 1.
DR SUPFAM; SSF48652; SSF48652; 1.
DR PROSITE; PS00421; TM4_1; 1.
PE 2: Evidence at transcript level;
KW Glycoprotein; Membrane; Reference proteome; Transmembrane;
KW Transmembrane helix.
FT CHAIN 1..239
FT /note="Tetraspanin-9"
FT /id="PRO_0000375886"
FT TOPO_DOM 1..13
FT /note="Cytoplasmic"
FT /evidence="ECO:0000255"
FT TRANSMEM 14..34
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TOPO_DOM 35..55
FT /note="Extracellular"
FT /evidence="ECO:0000255"
FT TRANSMEM 56..76
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TOPO_DOM 77..85
FT /note="Cytoplasmic"
FT /evidence="ECO:0000255"
FT TRANSMEM 86..106
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TOPO_DOM 107..203
FT /note="Extracellular"
FT /evidence="ECO:0000255"
FT TRANSMEM 204..224
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TOPO_DOM 225..239
FT /note="Cytoplasmic"
FT /evidence="ECO:0000255"
FT CARBOHYD 180
FT /note="N-linked (GlcNAc...) asparagine"
FT /evidence="ECO:0000255"
SQ SEQUENCE 239 AA; 26753 MW; E76BD6CEC25EB23F CRC64;
MARGCLCCLK YMMFLFNLIF WLCGCGLLGV GIWLSVSQGN FATFSPSFPS LSAANLVIAI
GTIVMVTGFL GCLGAIKENK CLLLSFFIIL LIILLAELIL LILFFVYMDK VNENAKQDLK
DGLLLYNTEN NVGLKNAWNI IQAEMHCCGV TDYTDWYPVL GENTVPDRCC MENSQDCGHN
STSLVWKTGC YEKVKMWFDD NKHVLGTIGM CILIIQILGM AFSMTLFQQI HRTGKKYDA