ID   TSNAX_SCHPO             Reviewed;         231 AA.
AC   O74955;
DT   14-OCT-2008, integrated into UniProtKB/Swiss-Prot.
DT   01-NOV-1998, sequence version 1.
DT   25-MAY-2022, entry version 110.
DE   RecName: Full=Translin-associated protein X homolog {ECO:0000250|UniProtKB:Q9JHB5, ECO:0000303|PubMed:16043634};
GN   ORFNames=SPCC736.09c;
OS   Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast).
OC   Eukaryota; Fungi; Dikarya; Ascomycota; Taphrinomycotina;
OC   Schizosaccharomycetes; Schizosaccharomycetales; Schizosaccharomycetaceae;
OC   Schizosaccharomyces.
OX   NCBI_TaxID=284812;
RN   [1] {ECO:0000312|EMBL:CAA19273.1}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=972 / ATCC 24843;
RX   PubMed=11859360; DOI=10.1038/nature724;
RA   Wood V., Gwilliam R., Rajandream M.A., Lyne M.H., Lyne R., Stewart A.,
RA   Sgouros J.G., Peat N., Hayles J., Baker S.G., Basham D., Bowman S.,
RA   Brooks K., Brown D., Brown S., Chillingworth T., Churcher C.M., Collins M.,
RA   Connor R., Cronin A., Davis P., Feltwell T., Fraser A., Gentles S.,
RA   Goble A., Hamlin N., Harris D.E., Hidalgo J., Hodgson G., Holroyd S.,
RA   Hornsby T., Howarth S., Huckle E.J., Hunt S., Jagels K., James K.D.,
RA   Jones L., Jones M., Leather S., McDonald S., McLean J., Mooney P.,
RA   Moule S., Mungall K.L., Murphy L.D., Niblett D., Odell C., Oliver K.,
RA   O'Neil S., Pearson D., Quail M.A., Rabbinowitsch E., Rutherford K.M.,
RA   Rutter S., Saunders D., Seeger K., Sharp S., Skelton J., Simmonds M.N.,
RA   Squares R., Squares S., Stevens K., Taylor K., Taylor R.G., Tivey A.,
RA   Walsh S.V., Warren T., Whitehead S., Woodward J.R., Volckaert G., Aert R.,
RA   Robben J., Grymonprez B., Weltjens I., Vanstreels E., Rieger M.,
RA   Schaefer M., Mueller-Auer S., Gabel C., Fuchs M., Duesterhoeft A.,
RA   Fritzc C., Holzer E., Moestl D., Hilbert H., Borzym K., Langer I., Beck A.,
RA   Lehrach H., Reinhardt R., Pohl T.M., Eger P., Zimmermann W., Wedler H.,
RA   Wambutt R., Purnelle B., Goffeau A., Cadieu E., Dreano S., Gloux S.,
RA   Lelaure V., Mottier S., Galibert F., Aves S.J., Xiang Z., Hunt C.,
RA   Moore K., Hurst S.M., Lucas M., Rochet M., Gaillardin C., Tallada V.A.,
RA   Garzon A., Thode G., Daga R.R., Cruzado L., Jimenez J., Sanchez M.,
RA   del Rey F., Benito J., Dominguez A., Revuelta J.L., Moreno S.,
RA   Armstrong J., Forsburg S.L., Cerutti L., Lowe T., McCombie W.R.,
RA   Paulsen I., Potashkin J., Shpakovski G.V., Ussery D., Barrell B.G.,
RA   Nurse P.;
RT   "The genome sequence of Schizosaccharomyces pombe.";
RL   Nature 415:871-880(2002).
RN   [2] {ECO:0000305}
RP   DISRUPTION PHENOTYPE.
RX   PubMed=16043634; DOI=10.1093/nar/gki727;
RA   Laufman O., Ben Yosef R., Adir N., Manor H.;
RT   "Cloning and characterization of the Schizosaccharomyces pombe homologs of
RT   the human protein translin and the translin-associated protein TRAX.";
RL   Nucleic Acids Res. 33:4128-4139(2005).
RN   [3] {ECO:0000305}
RP   SUBCELLULAR LOCATION [LARGE SCALE ANALYSIS].
RX   PubMed=16823372; DOI=10.1038/nbt1222;
RA   Matsuyama A., Arai R., Yashiroda Y., Shirai A., Kamata A., Sekido S.,
RA   Kobayashi Y., Hashimoto A., Hamamoto M., Hiraoka Y., Horinouchi S.,
RA   Yoshida M.;
RT   "ORFeome cloning and global analysis of protein localization in the fission
RT   yeast Schizosaccharomyces pombe.";
RL   Nat. Biotechnol. 24:841-847(2006).
CC   -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000269|PubMed:16823372}. Nucleus
CC       {ECO:0000269|PubMed:16823372}.
CC   -!- DISRUPTION PHENOTYPE: Deletion of both tsn1 and trax results in
CC       slightly stimulated cell proliferation. {ECO:0000269|PubMed:16043634}.
CC   -!- SIMILARITY: Belongs to the translin family. {ECO:0000255}.
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DR   EMBL; CU329672; CAA19273.1; -; Genomic_DNA.
DR   PIR; T41566; T41566.
DR   RefSeq; NP_587780.1; NM_001022773.2.
DR   AlphaFoldDB; O74955; -.
DR   SMR; O74955; -.
DR   BioGRID; 276018; 7.
DR   STRING; 4896.SPCC736.09c.1; -.
DR   iPTMnet; O74955; -.
DR   MaxQB; O74955; -.
DR   PaxDb; O74955; -.
DR   EnsemblFungi; SPCC736.09c.1; SPCC736.09c.1:pep; SPCC736.09c.
DR   GeneID; 2539455; -.
DR   KEGG; spo:SPCC736.09c; -.
DR   PomBase; SPCC736.09c; -.
DR   VEuPathDB; FungiDB:SPCC736.09c; -.
DR   eggNOG; KOG3066; Eukaryota.
DR   HOGENOM; CLU_067225_2_1_1; -.
DR   InParanoid; O74955; -.
DR   OMA; DTCMETC; -.
DR   PhylomeDB; O74955; -.
DR   Reactome; R-SPO-426486; Small interfering RNA (siRNA) biogenesis.
DR   PRO; PR:O74955; -.
DR   Proteomes; UP000002485; Chromosome III.
DR   GO; GO:0005737; C:cytoplasm; IBA:GO_Central.
DR   GO; GO:0005829; C:cytosol; HDA:PomBase.
DR   GO; GO:0005634; C:nucleus; HDA:PomBase.
DR   GO; GO:0004521; F:endoribonuclease activity; IBA:GO_Central.
DR   GO; GO:0003723; F:RNA binding; IBA:GO_Central.
DR   GO; GO:0043565; F:sequence-specific DNA binding; IEA:InterPro.
DR   GO; GO:0008033; P:tRNA processing; TAS:PomBase.
DR   Gene3D; 1.20.58.190; -; 1.
DR   Gene3D; 1.20.58.200; -; 1.
DR   InterPro; IPR016069; Translin_C.
DR   InterPro; IPR002848; Translin_fam.
DR   InterPro; IPR016068; Translin_N.
DR   InterPro; IPR036081; Translin_sf.
DR   PANTHER; PTHR10741; PTHR10741; 1.
DR   Pfam; PF01997; Translin; 1.
DR   SUPFAM; SSF74784; SSF74784; 1.
PE   3: Inferred from homology;
KW   Cytoplasm; Nucleus; Reference proteome.
FT   CHAIN           1..231
FT                   /note="Translin-associated protein X homolog"
FT                   /id="PRO_0000352756"
SQ   SEQUENCE   231 AA;  26775 MW;  C2342E9790F5C2D7 CRC64;
     MEEEFLSFKN FLQEDQDKRE KIIRLSREIT IQSKRMIFLL HQTSSSDGFP LPKDFDRTSI
     FEKKIHKELE SLKRELAGLN ADKFSSACTH GLQEYVEAVT FKFWLQTGTL LSCKDSSFRI
     SINFIDYVLG VCDMTGEIMR FLVTNGSKFS VQQLTQQVKF LRGLHKNCSE IEHLPSKVKS
     ELQQKLSVME NSISKVEGIC YSKILREADK RYLNLEVDTA TPPEEKRLRS T