C3P1_HUMAN
ID C3P1_HUMAN Reviewed; 363 AA.
AC Q6ZMU1;
DT 22-JUL-2008, integrated into UniProtKB/Swiss-Prot.
DT 02-NOV-2010, sequence version 3.
DT 25-MAY-2022, entry version 94.
DE RecName: Full=Putative protein C3P1;
GN Name=C3P1;
OS Homo sapiens (Human).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae;
OC Homo.
OX NCBI_TaxID=9606;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA], AND VARIANT ARG-172.
RC TISSUE=Liver;
RX PubMed=14702039; DOI=10.1038/ng1285;
RA Ota T., Suzuki Y., Nishikawa T., Otsuki T., Sugiyama T., Irie R.,
RA Wakamatsu A., Hayashi K., Sato H., Nagai K., Kimura K., Makita H.,
RA Sekine M., Obayashi M., Nishi T., Shibahara T., Tanaka T., Ishii S.,
RA Yamamoto J., Saito K., Kawai Y., Isono Y., Nakamura Y., Nagahari K.,
RA Murakami K., Yasuda T., Iwayanagi T., Wagatsuma M., Shiratori A., Sudo H.,
RA Hosoiri T., Kaku Y., Kodaira H., Kondo H., Sugawara M., Takahashi M.,
RA Kanda K., Yokoi T., Furuya T., Kikkawa E., Omura Y., Abe K., Kamihara K.,
RA Katsuta N., Sato K., Tanikawa M., Yamazaki M., Ninomiya K., Ishibashi T.,
RA Yamashita H., Murakawa K., Fujimori K., Tanai H., Kimata M., Watanabe M.,
RA Hiraoka S., Chiba Y., Ishida S., Ono Y., Takiguchi S., Watanabe S.,
RA Yosida M., Hotuta T., Kusano J., Kanehori K., Takahashi-Fujii A., Hara H.,
RA Tanase T.-O., Nomura Y., Togiya S., Komai F., Hara R., Takeuchi K.,
RA Arita M., Imose N., Musashino K., Yuuki H., Oshima A., Sasaki N.,
RA Aotsuka S., Yoshikawa Y., Matsunawa H., Ichihara T., Shiohata N., Sano S.,
RA Moriya S., Momiyama H., Satoh N., Takami S., Terashima Y., Suzuki O.,
RA Nakagawa S., Senoh A., Mizoguchi H., Goto Y., Shimizu F., Wakebe H.,
RA Hishigaki H., Watanabe T., Sugiyama A., Takemoto M., Kawakami B.,
RA Yamazaki M., Watanabe K., Kumagai A., Itakura S., Fukuzumi Y., Fujimori Y.,
RA Komiyama M., Tashiro H., Tanigami A., Fujiwara T., Ono T., Yamada K.,
RA Fujii Y., Ozaki K., Hirao M., Ohmori Y., Kawabata A., Hikiji T.,
RA Kobatake N., Inagaki H., Ikema Y., Okamoto S., Okitani R., Kawakami T.,
RA Noguchi S., Itoh T., Shigeta K., Senba T., Matsumura K., Nakajima Y.,
RA Mizuno T., Morinaga M., Sasaki M., Togashi T., Oyama M., Hata H.,
RA Watanabe M., Komatsu T., Mizushima-Sugano J., Satoh T., Shirai Y.,
RA Takahashi Y., Nakagawa K., Okumura K., Nagase T., Nomura N., Kikuchi H.,
RA Masuho Y., Yamashita R., Nakai K., Yada T., Nakamura Y., Ohara O.,
RA Isogai T., Sugano S.;
RT "Complete sequencing and characterization of 21,243 full-length human
RT cDNAs.";
RL Nat. Genet. 36:40-45(2004).
RN [2]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX PubMed=15057824; DOI=10.1038/nature02399;
RA Grimwood J., Gordon L.A., Olsen A.S., Terry A., Schmutz J., Lamerdin J.E.,
RA Hellsten U., Goodstein D., Couronne O., Tran-Gyamfi M., Aerts A.,
RA Altherr M., Ashworth L., Bajorek E., Black S., Branscomb E., Caenepeel S.,
RA Carrano A.V., Caoile C., Chan Y.M., Christensen M., Cleland C.A.,
RA Copeland A., Dalin E., Dehal P., Denys M., Detter J.C., Escobar J.,
RA Flowers D., Fotopulos D., Garcia C., Georgescu A.M., Glavina T., Gomez M.,
RA Gonzales E., Groza M., Hammon N., Hawkins T., Haydu L., Ho I., Huang W.,
RA Israni S., Jett J., Kadner K., Kimball H., Kobayashi A., Larionov V.,
RA Leem S.-H., Lopez F., Lou Y., Lowry S., Malfatti S., Martinez D.,
RA McCready P.M., Medina C., Morgan J., Nelson K., Nolan M., Ovcharenko I.,
RA Pitluck S., Pollard M., Popkie A.P., Predki P., Quan G., Ramirez L.,
RA Rash S., Retterer J., Rodriguez A., Rogers S., Salamov A., Salazar A.,
RA She X., Smith D., Slezak T., Solovyev V., Thayer N., Tice H., Tsai M.,
RA Ustaszewska A., Vo N., Wagner M., Wheeler J., Wu K., Xie G., Yang J.,
RA Dubchak I., Furey T.S., DeJong P., Dickson M., Gordon D., Eichler E.E.,
RA Pennacchio L.A., Richardson P., Stubbs L., Rokhsar D.S., Myers R.M.,
RA Rubin E.M., Lucas S.M.;
RT "The DNA sequence and biology of human chromosome 19.";
RL Nature 428:529-535(2004).
CC -!- CAUTION: Could be the product of a pseudogene. {ECO:0000305}.
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DR EMBL; AK131489; BAD18634.1; -; mRNA.
DR EMBL; AC020931; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR AlphaFoldDB; Q6ZMU1; -.
DR SMR; Q6ZMU1; -.
DR IntAct; Q6ZMU1; 1.
DR BioMuta; HGNC:34414; -.
DR MassIVE; Q6ZMU1; -.
DR PeptideAtlas; Q6ZMU1; -.
DR PRIDE; Q6ZMU1; -.
DR ProteomicsDB; 67917; -.
DR GeneCards; C3P1; -.
DR HGNC; HGNC:34414; C3P1.
DR neXtProt; NX_Q6ZMU1; -.
DR InParanoid; Q6ZMU1; -.
DR PhylomeDB; Q6ZMU1; -.
DR Pharos; Q6ZMU1; Tdark.
DR Proteomes; UP000005640; Unplaced.
DR RNAct; Q6ZMU1; protein.
DR GO; GO:0005615; C:extracellular space; IEA:InterPro.
DR GO; GO:0004866; F:endopeptidase inhibitor activity; IEA:InterPro.
DR Gene3D; 2.60.40.10; -; 1.
DR InterPro; IPR011626; Alpha-macroglobulin_TED.
DR InterPro; IPR013783; Ig-like_fold.
DR InterPro; IPR001599; Macroglobln_a2.
DR InterPro; IPR008930; Terpenoid_cyclase/PrenylTrfase.
DR Pfam; PF00207; A2M; 1.
DR Pfam; PF07678; TED_complement; 1.
DR SMART; SM01360; A2M; 1.
DR SUPFAM; SSF48239; SSF48239; 1.
PE 5: Uncertain;
KW Reference proteome.
FT CHAIN 1..363
FT /note="Putative protein C3P1"
FT /id="PRO_0000343664"
FT VARIANT 172
FT /note="Q -> R (in dbSNP:rs8113341)"
FT /evidence="ECO:0000269|PubMed:14702039"
FT /id="VAR_044412"
FT VARIANT 230
FT /note="D -> N (in dbSNP:rs10403787)"
FT /id="VAR_044413"
FT VARIANT 251
FT /note="D -> G (in dbSNP:rs1993466)"
FT /id="VAR_044414"
FT VARIANT 262
FT /note="L -> R (in dbSNP:rs4552116)"
FT /id="VAR_044415"
SQ SEQUENCE 363 AA; 40197 MW; A1A6092CBF572942 CRC64;
MPVRTLFPES WLWRKFTLPK SKSGISHYPI SVKVPDSITT WQFVVVSLKA GQGLCVSDPF
ELTVMKSFFV DLKLPSSVIR NEQVQIQAML YNFRDRQAKV RVEFPHKETL CSASKPGAPS
HQAGVQIQQT SYSIVLEPQG QTQTKLVPRQ EFLNMVPDTE AEVFISVQGY TQMLTHRSSD
GTYHTSKGNP GSTWLTSYVF RVFALAYSMM TTQVLSLSSL CDMANWIIID RQAEDGHFLE
KGPVVMTSMQ DGYQGSEEDV SLTALVLIAL NEGKELCRQK NLMASIERAR GFLERKLPDI
QTTFAVAIAS YALALANSSQ ANDCLDSFAS PSGCGMLLNQ PQSWSGEGVI SNPAMCYSSL
SVS
