ID   TSP_BPBMU               Reviewed;         477 AA.
AC   Q6QIB0;
DT   29-APR-2015, integrated into UniProtKB/Swiss-Prot.
DT   05-JUL-2004, sequence version 1.
DT   23-FEB-2022, entry version 47.
DE   RecName: Full=Tail sheath protein;
DE            Short=TSP;
GN   ORFNames=BcepMu39 {ECO:0000312|EMBL:AAS47878.1};
OS   Burkholderia phage BcepMu (isolate -/United States/Summer/2002)
OS   (Bacteriophage BcepMu).
OC   Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes;
OC   Caudovirales; Myoviridae; Bcepmuvirus.
OX   NCBI_TaxID=1283335;
OH   NCBI_TaxID=216591; Burkholderia cenocepacia (strain ATCC BAA-245 / DSM 16553 / LMG 16656 / NCTC 13227 / J2315 / CF5610) (Burkholderia cepacia (strain J2315)).
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=Isolate -/United States/Summer/2002
RC   {ECO:0000312|Proteomes:UP000011237};
RX   PubMed=15184022; DOI=10.1016/j.jmb.2004.04.053;
RA   Summer E.J., Gonzalez C.F., Carlisle T., Mebane L.M., Cass A.M.,
RA   Savva C.G., LiPuma J., Young R.;
RT   "Burkholderia cenocepacia phage BcepMu and a family of Mu-like phages
RT   encoding potential pathogenesis factors.";
RL   J. Mol. Biol. 340:49-65(2004).
CC   -!- FUNCTION: Polymerizes as an extended structure around the baseplate-
CC       tail tube complex. During ejection, the sheath shifts to a contracted
CC       form, thereby making the inner tail tube protrude through the host cell
CC       envelope. {ECO:0000250|UniProtKB:P79678}.
CC   -!- SUBUNIT: Homomultimer. {ECO:0000250|UniProtKB:P79678}.
CC   -!- SUBCELLULAR LOCATION: Virion {ECO:0000250|UniProtKB:P79678}. Host
CC       cytoplasm {ECO:0000250|UniProtKB:P79678}. Note=Tail.
CC       {ECO:0000250|UniProtKB:P79678}.
CC   -!- SIMILARITY: Belongs to the myoviridae tail sheath protein family.
CC       {ECO:0000305}.
CC   ---------------------------------------------------------------------------
CC   Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC   Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC   ---------------------------------------------------------------------------
DR   EMBL; AY539836; AAS47878.1; -; Genomic_DNA.
DR   RefSeq; YP_024712.1; NC_005882.1.
DR   SMR; Q6QIB0; -.
DR   GeneID; 2845953; -.
DR   KEGG; vg:2845953; -.
DR   Proteomes; UP000011237; Genome.
DR   GO; GO:0030430; C:host cell cytoplasm; IEA:UniProtKB-SubCell.
DR   GO; GO:0098027; C:virus tail, sheath; IEA:UniProtKB-KW.
DR   GO; GO:0099000; P:viral genome ejection through host cell envelope, contractile tail mechanism; IEA:UniProtKB-KW.
DR   InterPro; IPR035089; Phage_sheath_subtilisin.
DR   InterPro; IPR020287; Tail_sheath_C.
DR   Pfam; PF04984; Phage_sheath_1; 1.
DR   Pfam; PF17482; Phage_sheath_1C; 1.
PE   3: Inferred from homology;
KW   Host cytoplasm; Reference proteome; Viral contractile tail ejection system;
KW   Viral genome ejection through host cell envelope;
KW   Viral penetration into host cytoplasm; Viral tail protein;
KW   Viral tail sheath protein; Virion; Virus entry into host cell.
FT   CHAIN           1..477
FT                   /note="Tail sheath protein"
FT                   /id="PRO_0000432775"
SQ   SEQUENCE   477 AA;  50927 MW;  6358D56CC6C2D91B CRC64;
     MAANYLHGVE TIEKETGSRP VKVVKSAVIG LIGTAPIGPV NTPVQSLSDV DAAQFGPQLA
     GFTIPQALDA VYDYGSGTVI VINVLDPAVH KSNAANEPVT FDAATGRAKL AHPAAANLVL
     KNDSGGTTYA EGTDYAVDLI NGVITRIKTG TIPPGATAAK ATYDYADPTK VTAADIIGAV
     NAAGMRTGMK ALKDTYNLYG YFSKILIAPA YCTQNSVSVE LEAMAVQLGA IAYIDAPIGT
     TLAQALAGRG PAGTINFNTS SDRVRLCYPH VKVYDTATNA ERLEPLSSRA AGLRARVDLD
     KGYWWSSSNQ QLVGVTGVER PLSAMIDDPQ SDVNMLNEQG ITTVFSSYGS GLRLWGNRTA
     AWPTVTHMRN FENVRRTGDV INESLRYFSQ QFVDAPIDQG LIDSLVESVN GFGRKLIGDG
     ALLGFKAWFD PARNPKEELA AGHLLINYKY TVPPPLERLT YETEITSEYL LTLKGGN