ID   TSP_BPP2                Reviewed;         396 AA.
AC   P22501;
DT   01-AUG-1991, integrated into UniProtKB/Swiss-Prot.
DT   23-JAN-2007, sequence version 2.
DT   23-FEB-2022, entry version 74.
DE   RecName: Full=Tail sheath protein;
DE            Short=TSP;
DE   AltName: Full=Major tail sheath protein;
DE   AltName: Full=Protein FI;
GN   Name=FI;
OS   Escherichia phage P2 (Bacteriophage P2).
OC   Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes;
OC   Caudovirales; Myoviridae; Peduovirinae; Peduovirus.
OX   NCBI_TaxID=10679;
OH   NCBI_TaxID=543; Enterobacteriaceae.
RN   [1]
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA], AND PROTEIN SEQUENCE OF 2-11.
RX   PubMed=1825255; DOI=10.1016/0042-6822(91)90502-3;
RA   Temple L.M., Forsburg S.L., Calendar R., Christie G.E.;
RT   "Nucleotide sequence of the genes encoding the major tail sheath and tail
RT   tube proteins of bacteriophage P2.";
RL   Virology 181:353-358(1991).
RN   [2]
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA] OF 1-115.
RX   PubMed=3981640; DOI=10.1016/0022-2836(85)90226-8;
RA   Christie G.E., Calendar R.;
RT   "Bacteriophage P2 late promoters. II. Comparison of the four late promoter
RT   sequences.";
RL   J. Mol. Biol. 181:373-382(1985).
CC   -!- FUNCTION: Polymerizes as an extended helical structure around the
CC       baseplate-tail tube complex. During ejection, the sheath shifts to a
CC       contracted form, thereby making the inner tail tube protrude through
CC       the host cell envelope. {ECO:0000250|UniProtKB:P79678}.
CC   -!- SUBUNIT: Homomultimer. {ECO:0000250|UniProtKB:P79678}.
CC   -!- SUBCELLULAR LOCATION: Virion {ECO:0000250|UniProtKB:P79678}. Host
CC       cytoplasm {ECO:0000250|UniProtKB:P79678}. Note=Tail.
CC       {ECO:0000250|UniProtKB:P79678}.
CC   -!- SIMILARITY: Belongs to the myoviridae tail sheath protein family.
CC       {ECO:0000305}.
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DR   EMBL; AF063097; AAD03289.1; -; Genomic_DNA.
DR   PIR; S26391; S26391.
DR   RefSeq; NP_046778.1; NC_001895.1.
DR   SMR; P22501; -.
DR   GeneID; 1261516; -.
DR   KEGG; vg:1261516; -.
DR   Proteomes; UP000009092; Genome.
DR   GO; GO:0030430; C:host cell cytoplasm; IEA:UniProtKB-SubCell.
DR   GO; GO:0098027; C:virus tail, sheath; IEA:UniProtKB-KW.
DR   GO; GO:0099000; P:viral genome ejection through host cell envelope, contractile tail mechanism; IEA:UniProtKB-KW.
DR   InterPro; IPR035089; Phage_sheath_subtilisin.
DR   InterPro; IPR020287; Tail_sheath_C.
DR   Pfam; PF04984; Phage_sheath_1; 1.
DR   Pfam; PF17482; Phage_sheath_1C; 1.
PE   1: Evidence at protein level;
KW   Direct protein sequencing; Host cytoplasm; Late protein;
KW   Reference proteome; Viral contractile tail ejection system;
KW   Viral genome ejection through host cell envelope;
KW   Viral penetration into host cytoplasm; Viral tail protein;
KW   Viral tail sheath protein; Virion; Virus entry into host cell.
FT   INIT_MET        1
FT                   /note="Removed; by host"
FT                   /evidence="ECO:0000269|PubMed:1825255"
FT   CHAIN           2..396
FT                   /note="Tail sheath protein"
FT                   /id="PRO_0000165250"
SQ   SEQUENCE   396 AA;  43144 MW;  0BA6C8811E176EA8 CRC64;
     MSDYHHGVQV LEINEGTRVI STVSTAIVGM VCTASDADAE TFPLNKPVLI TNVQSAISKA
     GKKGTLAASL QAIADQSKPV TVVMRVEDGT GDDEETKLAQ TVSNIIGTTD ENGQYTGLKA
     MLAAESVTGV KPRILGVPGL DTKEVAVALA SVCQKLRAFG YISAWGCKTI SEVKAYRQNF
     SQRELMVIWP DFLAWDTVTS TTATAYATAR ALGLRAKIDQ EQGWHKTLSN VGVNGVTGIS
     ASVFWDLQES GTDADLLNES GVTTLIRRDG FRFWGNRTCS DDPLFLFENY TRTAQVVADT
     MAEAHMWAVD KPITATLIRD IVDGINAKFR ELKTNGYIVD ATCWFSEESN DAETLKAGKL
     YIDYDYTPVP PLENLTLRQR ITDKYLANLV TSVNSN