ID   C42S1_CHICK             Reviewed;          78 AA.
AC   Q5ZKB1;
DT   20-MAY-2008, integrated into UniProtKB/Swiss-Prot.
DT   23-NOV-2004, sequence version 1.
DT   03-AUG-2022, entry version 76.
DE   RecName: Full=CDC42 small effector protein 1;
GN   Name=CDC42SE1; ORFNames=RCJMB04_11p12;
OS   Gallus gallus (Chicken).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC   Archelosauria; Archosauria; Dinosauria; Saurischia; Theropoda;
OC   Coelurosauria; Aves; Neognathae; Galloanserae; Galliformes; Phasianidae;
OC   Phasianinae; Gallus.
OX   NCBI_TaxID=9031;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC   STRAIN=CB; TISSUE=Bursa of Fabricius;
RX   PubMed=15642098; DOI=10.1186/gb-2004-6-1-r6;
RA   Caldwell R.B., Kierzek A.M., Arakawa H., Bezzubov Y., Zaim J., Fiedler P.,
RA   Kutter S., Blagodatski A., Kostovska D., Koter M., Plachy J., Carninci P.,
RA   Hayashizaki Y., Buerstedde J.-M.;
RT   "Full-length cDNAs from chicken bursal lymphocytes to facilitate gene
RT   function analysis.";
RL   Genome Biol. 6:R6.1-R6.9(2005).
CC   -!- FUNCTION: Probably involved in the organization of the actin
CC       cytoskeleton by acting downstream of CDC42, inducing actin filament
CC       assembly. {ECO:0000250}.
CC   -!- SUBCELLULAR LOCATION: Cytoplasm, cytoskeleton {ECO:0000250}. Cell
CC       membrane {ECO:0000250}; Lipid-anchor {ECO:0000250}.
CC   -!- SIMILARITY: Belongs to the CDC42SE/SPEC family. {ECO:0000305}.
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DR   EMBL; AJ720173; CAG31832.1; -; mRNA.
DR   RefSeq; XP_003642732.1; XM_003642684.2.
DR   AlphaFoldDB; Q5ZKB1; -.
DR   STRING; 9031.ENSGALP00000041631; -.
DR   Ensembl; ENSGALT00000043843; ENSGALP00000041631; ENSGALG00000028119.
DR   GeneID; 100857323; -.
DR   KEGG; gga:100857323; -.
DR   CTD; 56882; -.
DR   VEuPathDB; HostDB:geneid_100857323; -.
DR   eggNOG; ENOG502S499; Eukaryota.
DR   GeneTree; ENSGT00940000160112; -.
DR   HOGENOM; CLU_173417_1_0_1; -.
DR   InParanoid; Q5ZKB1; -.
DR   OMA; DRPWNNS; -.
DR   OrthoDB; 1646014at2759; -.
DR   PhylomeDB; Q5ZKB1; -.
DR   PRO; PR:Q5ZKB1; -.
DR   Proteomes; UP000000539; Chromosome 25.
DR   Bgee; ENSGALG00000028119; Expressed in granulocyte and 12 other tissues.
DR   GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-KW.
DR   GO; GO:0005856; C:cytoskeleton; IEA:UniProtKB-SubCell.
DR   GO; GO:0005886; C:plasma membrane; IBA:GO_Central.
DR   GO; GO:0031267; F:small GTPase binding; IEA:InterPro.
DR   GO; GO:0008360; P:regulation of cell shape; IEA:UniProtKB-KW.
DR   GO; GO:0035023; P:regulation of Rho protein signal transduction; IEA:InterPro.
DR   Gene3D; 3.90.810.10; -; 1.
DR   InterPro; IPR000095; CRIB_dom.
DR   InterPro; IPR036936; CRIB_dom_sf.
DR   InterPro; IPR039056; SPEC.
DR   PANTHER; PTHR13502; PTHR13502; 1.
DR   Pfam; PF00786; PBD; 1.
DR   PROSITE; PS50108; CRIB; 1.
PE   3: Inferred from homology;
KW   Cell membrane; Cell shape; Cytoplasm; Cytoskeleton; Lipoprotein; Membrane;
KW   Palmitate; Reference proteome.
FT   CHAIN           1..78
FT                   /note="CDC42 small effector protein 1"
FT                   /id="PRO_0000334633"
FT   DOMAIN          30..43
FT                   /note="CRIB"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00057"
FT   LIPID           10
FT                   /note="S-palmitoyl cysteine"
FT                   /evidence="ECO:0000250"
FT   LIPID           11
FT                   /note="S-palmitoyl cysteine"
FT                   /evidence="ECO:0000250"
SQ   SEQUENCE   78 AA;  8840 MW;  3FF4FDFE8B83B1A8 CRC64;
     MSDFWHKLGC CVVEKPQPKK RRRRIDRSMI GEPMNFVHLT HIGSGDMAAG EGLPMTGAVQ
     EMRSKGGRER QWSSSRVL