ID   TSP_MOUSE               Reviewed;         124 AA.
AC   P13438;
DT   01-JAN-1990, integrated into UniProtKB/Swiss-Prot.
DT   01-FEB-1996, sequence version 2.
DT   25-MAY-2022, entry version 106.
DE   RecName: Full=Trophoblast-specific protein alpha;
DE   Flags: Precursor;
GN   Name=Tpbpa; Synonyms=Tpbp;
OS   Mus musculus (Mouse).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC   Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae;
OC   Murinae; Mus; Mus.
OX   NCBI_TaxID=10090;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [MRNA].
RC   STRAIN=CD-1;
RX   PubMed=3215514; DOI=10.1101/gad.2.12a.1639;
RA   Lescisin K.R., Varmuza S., Rossant J.;
RT   "Isolation and characterization of a novel trophoblast-specific cDNA in the
RT   mouse.";
RL   Genes Dev. 2:1639-1646(1988).
CC   -!- FUNCTION: It may be a growth factor/hormone, perhaps involved in
CC       interaction between the maternal and fetal systems in maintenance of
CC       pregnancy.
CC   -!- SUBCELLULAR LOCATION: Secreted, extracellular space {ECO:0000305}.
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DR   EMBL; X17071; CAA34917.1; -; mRNA.
DR   CCDS; CCDS36693.1; -.
DR   PIR; A30043; A30043.
DR   AlphaFoldDB; P13438; -.
DR   SMR; P13438; -.
DR   STRING; 10090.ENSMUSP00000021885; -.
DR   PaxDb; P13438; -.
DR   PRIDE; P13438; -.
DR   MGI; MGI:98795; Tpbpa.
DR   InParanoid; P13438; -.
DR   PhylomeDB; P13438; -.
DR   ChiTaRS; Tpbpa; mouse.
DR   PRO; PR:P13438; -.
DR   Proteomes; UP000000589; Unplaced.
DR   RNAct; P13438; protein.
DR   GO; GO:0005615; C:extracellular space; IEA:UniProtKB-SubCell.
DR   GO; GO:0071407; P:cellular response to organic cyclic compound; IDA:MGI.
DR   GO; GO:0007254; P:JNK cascade; IDA:MGI.
PE   2: Evidence at transcript level;
KW   Reference proteome; Secreted; Signal.
FT   SIGNAL          1..18
FT                   /evidence="ECO:0000255"
FT   CHAIN           19..124
FT                   /note="Trophoblast-specific protein alpha"
FT                   /id="PRO_0000022600"
FT   REGION          51..74
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          91..124
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   124 AA;  13948 MW;  BB5E3AFF955AA2C4 CRC64;
     MTPTIFLVIL CLGVASAVIV PEAQLDAELQ EQKDKEVLIK AVWSKFMKTN KLHSSENDQE
     TEGSNIEMSA SGQLTDEELM KIMTTVLHPM FEEEENKPQP VVDDPEFEDY TESGDGFFVP
     NQPQ