ID   TSR4_SCHPO              Reviewed;         396 AA.
AC   P87156;
DT   15-JUL-1998, integrated into UniProtKB/Swiss-Prot.
DT   01-JUL-1997, sequence version 1.
DT   03-AUG-2022, entry version 106.
DE   RecName: Full=Probable 20S rRNA accumulation protein 4;
GN   ORFNames=SPBC25H2.15;
OS   Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast).
OC   Eukaryota; Fungi; Dikarya; Ascomycota; Taphrinomycotina;
OC   Schizosaccharomycetes; Schizosaccharomycetales; Schizosaccharomycetaceae;
OC   Schizosaccharomyces.
OX   NCBI_TaxID=284812;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=972 / ATCC 24843;
RX   PubMed=11859360; DOI=10.1038/nature724;
RA   Wood V., Gwilliam R., Rajandream M.A., Lyne M.H., Lyne R., Stewart A.,
RA   Sgouros J.G., Peat N., Hayles J., Baker S.G., Basham D., Bowman S.,
RA   Brooks K., Brown D., Brown S., Chillingworth T., Churcher C.M., Collins M.,
RA   Connor R., Cronin A., Davis P., Feltwell T., Fraser A., Gentles S.,
RA   Goble A., Hamlin N., Harris D.E., Hidalgo J., Hodgson G., Holroyd S.,
RA   Hornsby T., Howarth S., Huckle E.J., Hunt S., Jagels K., James K.D.,
RA   Jones L., Jones M., Leather S., McDonald S., McLean J., Mooney P.,
RA   Moule S., Mungall K.L., Murphy L.D., Niblett D., Odell C., Oliver K.,
RA   O'Neil S., Pearson D., Quail M.A., Rabbinowitsch E., Rutherford K.M.,
RA   Rutter S., Saunders D., Seeger K., Sharp S., Skelton J., Simmonds M.N.,
RA   Squares R., Squares S., Stevens K., Taylor K., Taylor R.G., Tivey A.,
RA   Walsh S.V., Warren T., Whitehead S., Woodward J.R., Volckaert G., Aert R.,
RA   Robben J., Grymonprez B., Weltjens I., Vanstreels E., Rieger M.,
RA   Schaefer M., Mueller-Auer S., Gabel C., Fuchs M., Duesterhoeft A.,
RA   Fritzc C., Holzer E., Moestl D., Hilbert H., Borzym K., Langer I., Beck A.,
RA   Lehrach H., Reinhardt R., Pohl T.M., Eger P., Zimmermann W., Wedler H.,
RA   Wambutt R., Purnelle B., Goffeau A., Cadieu E., Dreano S., Gloux S.,
RA   Lelaure V., Mottier S., Galibert F., Aves S.J., Xiang Z., Hunt C.,
RA   Moore K., Hurst S.M., Lucas M., Rochet M., Gaillardin C., Tallada V.A.,
RA   Garzon A., Thode G., Daga R.R., Cruzado L., Jimenez J., Sanchez M.,
RA   del Rey F., Benito J., Dominguez A., Revuelta J.L., Moreno S.,
RA   Armstrong J., Forsburg S.L., Cerutti L., Lowe T., McCombie W.R.,
RA   Paulsen I., Potashkin J., Shpakovski G.V., Ussery D., Barrell B.G.,
RA   Nurse P.;
RT   "The genome sequence of Schizosaccharomyces pombe.";
RL   Nature 415:871-880(2002).
RN   [2]
RP   SUBCELLULAR LOCATION [LARGE SCALE ANALYSIS].
RX   PubMed=16823372; DOI=10.1038/nbt1222;
RA   Matsuyama A., Arai R., Yashiroda Y., Shirai A., Kamata A., Sekido S.,
RA   Kobayashi Y., Hashimoto A., Hamamoto M., Hiraoka Y., Horinouchi S.,
RA   Yoshida M.;
RT   "ORFeome cloning and global analysis of protein localization in the fission
RT   yeast Schizosaccharomyces pombe.";
RL   Nat. Biotechnol. 24:841-847(2006).
CC   -!- FUNCTION: Required for processing of the 20S pre-rRNA at site D to
CC       generate mature 18S rRNA. {ECO:0000250}.
CC   -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000269|PubMed:16823372}. Nucleus,
CC       nucleolus {ECO:0000269|PubMed:16823372}.
CC   -!- SIMILARITY: Belongs to the TSR4 family. {ECO:0000305}.
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DR   EMBL; CU329671; CAB08774.1; -; Genomic_DNA.
DR   PIR; T40010; T40010.
DR   RefSeq; NP_596352.1; NM_001022272.1.
DR   AlphaFoldDB; P87156; -.
DR   BioGRID; 277145; 46.
DR   STRING; 4896.SPBC25H2.15.1; -.
DR   iPTMnet; P87156; -.
DR   MaxQB; P87156; -.
DR   PaxDb; P87156; -.
DR   PRIDE; P87156; -.
DR   EnsemblFungi; SPBC25H2.15.1; SPBC25H2.15.1:pep; SPBC25H2.15.
DR   GeneID; 2540619; -.
DR   KEGG; spo:SPBC25H2.15; -.
DR   PomBase; SPBC25H2.15; -.
DR   VEuPathDB; FungiDB:SPBC25H2.15; -.
DR   eggNOG; KOG2061; Eukaryota.
DR   HOGENOM; CLU_031771_1_1_1; -.
DR   InParanoid; P87156; -.
DR   OMA; ENLDWGV; -.
DR   PhylomeDB; P87156; -.
DR   PRO; PR:P87156; -.
DR   Proteomes; UP000002485; Chromosome II.
DR   GO; GO:0005737; C:cytoplasm; HDA:PomBase.
DR   GO; GO:0005829; C:cytosol; HDA:PomBase.
DR   GO; GO:0005730; C:nucleolus; HDA:PomBase.
DR   GO; GO:0005634; C:nucleus; HDA:PomBase.
DR   GO; GO:0030490; P:maturation of SSU-rRNA; ISO:PomBase.
DR   InterPro; IPR007320; PDCD2_C.
DR   Pfam; PF04194; PDCD2_C; 1.
PE   3: Inferred from homology;
KW   Cytoplasm; Nucleus; Reference proteome; rRNA processing.
FT   CHAIN           1..396
FT                   /note="Probable 20S rRNA accumulation protein 4"
FT                   /id="PRO_0000116493"
SQ   SEQUENCE   396 AA;  44276 MW;  F3C0DC1AEC9DDA52 CRC64;
     MSQKWVQTQA WLGFPDVPIS QEDKPDEYST FLGGFPVFFD GCSLNPNIIK CGNCKNLCRL
     LLQCYAPLEG DNLKERALYV WGCHNPSCRR VPNSIVCVRG VRLPLKSDIE AVKSPKAISH
     LEEKKSSPKE KKVNPFAITS ESSRGLNPFS DATSANNPFS LSTDVNPSKP SSNVFSKPSF
     AAKAQQSITD QQKTQAKTKT KHIALTTSGM SVHPPVTETY TYPVTEAFQG MFLGLDLEYV
     PQNKVNSKKD DFSTFKNYTP YLNDSSEAWE KESYEKSPSV YEKTFRLFSE KISHNPTQCL
     RYERGGTPLL ASGRDKLGQQ LKSVTNFGKS PVPLCPLCKS PRLFEMQLMP HAISILNDEI
     AEWSTILVAT CSMDCNPPIN KDRVGYAVEW VGIQWD