ID   TSTD2_PONAB             Reviewed;         516 AA.
AC   Q5RCP1;
DT   04-APR-2006, integrated into UniProtKB/Swiss-Prot.
DT   21-DEC-2004, sequence version 1.
DT   03-AUG-2022, entry version 69.
DE   RecName: Full=Thiosulfate sulfurtransferase/rhodanese-like domain-containing protein 2;
GN   Name=TSTD2;
OS   Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC   Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae;
OC   Pongo.
OX   NCBI_TaxID=9601;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC   TISSUE=Brain cortex;
RG   The German cDNA consortium;
RL   Submitted (NOV-2004) to the EMBL/GenBank/DDBJ databases.
CC   ---------------------------------------------------------------------------
CC   Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC   Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC   ---------------------------------------------------------------------------
DR   EMBL; CR858229; CAH90466.1; -; mRNA.
DR   RefSeq; NP_001125241.1; NM_001131769.1.
DR   RefSeq; XP_009242951.1; XM_009244676.1.
DR   AlphaFoldDB; Q5RCP1; -.
DR   SMR; Q5RCP1; -.
DR   STRING; 9601.ENSPPYP00000021767; -.
DR   Ensembl; ENSPPYT00000022657; ENSPPYP00000021767; ENSPPYG00000019425.
DR   GeneID; 100172136; -.
DR   KEGG; pon:100172136; -.
DR   CTD; 158427; -.
DR   eggNOG; ENOG502QSQK; Eukaryota.
DR   GeneTree; ENSGT00390000016307; -.
DR   InParanoid; Q5RCP1; -.
DR   OrthoDB; 1276106at2759; -.
DR   Proteomes; UP000001595; Chromosome 9.
DR   Gene3D; 3.40.250.10; -; 1.
DR   InterPro; IPR001763; Rhodanese-like_dom.
DR   InterPro; IPR036873; Rhodanese-like_dom_sf.
DR   InterPro; IPR022111; Rhodanese_C.
DR   InterPro; IPR020936; TrhO.
DR   InterPro; IPR040503; TRHO_N.
DR   PANTHER; PTHR43268; PTHR43268; 1.
DR   Pfam; PF00581; Rhodanese; 1.
DR   Pfam; PF12368; Rhodanese_C; 1.
DR   Pfam; PF17773; UPF0176_N; 1.
DR   SMART; SM00450; RHOD; 1.
DR   SUPFAM; SSF52821; SSF52821; 1.
DR   PROSITE; PS50206; RHODANESE_3; 1.
PE   2: Evidence at transcript level;
KW   Phosphoprotein; Reference proteome.
FT   CHAIN           1..516
FT                   /note="Thiosulfate sulfurtransferase/rhodanese-like domain-
FT                   containing protein 2"
FT                   /id="PRO_0000230675"
FT   DOMAIN          301..396
FT                   /note="Rhodanese"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00173"
FT   REGION          490..516
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   ACT_SITE        355
FT                   /note="Cysteine persulfide intermediate"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00173"
FT   MOD_RES         269
FT                   /note="Phosphoserine"
FT                   /evidence="ECO:0000250|UniProtKB:Q5T7W7"
SQ   SEQUENCE   516 AA;  58195 MW;  C13F1EBA2D0E4554 CRC64;
     MPSSTSPDQG DDLETCILRF SDLDLKDMSL INPSSSLKAE LDGSTKKKYS FAKKKAFALF
     VKTKEVPTKR SFECKEKLWK CCQQLFTDQT SIHRHVATQH ADEIYHQTAS ILKQLAVTLS
     TSKSLSSADE KNPLKECLPH SHDVSAWLPD ISCFNPDELI SGQGSEEGEV LLYYCYRDLE
     DPQWICAWQT ALCQQLHLTG KIRIAAEGIN GTVGGSKLAT RLYVEVMLSF PLFKDDLCKD
     DFKTSKGGAH CFPELRVGVF EEIVPMGISP KKISYKKPGI HLSPGEFHKE VEKFLSQANQ
     EQSDTILLDC RNFYESKIGR FQGCLAPDIR KFSYFPSYVD KNLELFREKR VLMYCTGGIR
     CERGSAYLKA KGVCKEVFQL KGGIHKYLEE FPDGFYKGKL FVFDERYALS YNSDVVSECS
     YCGARWDQYK LCSTPQCHQL VLTCPACQGQ GFTACCVTCQ DKGSRKVSGP MQDSFKEECE
     CTARRPRIPR ELLQHVRQPV SPEPGPDAEE DGPVLV