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TSX_MOUSE
ID   TSX_MOUSE               Reviewed;         144 AA.
AC   P70675;
DT   01-NOV-1997, integrated into UniProtKB/Swiss-Prot.
DT   01-FEB-1997, sequence version 1.
DT   03-AUG-2022, entry version 104.
DE   RecName: Full=Testis-specific protein TSX;
GN   Name=Tsx;
OS   Mus musculus (Mouse).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC   Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae;
OC   Murinae; Mus; Mus.
OX   NCBI_TaxID=10090;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA / MRNA].
RC   STRAIN=129/Sv; TISSUE=Testis;
RX   PubMed=8922998; DOI=10.1093/hmg/5.11.1713;
RA   Simmler M.-C., Cunningham D.B., Clerc P., Vermat T., Caudron B., Cruaud C.,
RA   Pawlak A., Szpirer C., Weissenbach J., Claverie J.-M., Avner P.;
RT   "A 94 kb genomic sequence 3' to the murine Xist gene reveals an AT rich
RT   region containing a new testis specific gene Tsx.";
RL   Hum. Mol. Genet. 5:1713-1726(1996).
RN   [2]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC   TISSUE=Testis;
RX   PubMed=15489334; DOI=10.1101/gr.2596504;
RG   The MGC Project Team;
RT   "The status, quality, and expansion of the NIH full-length cDNA project:
RT   the Mammalian Gene Collection (MGC).";
RL   Genome Res. 14:2121-2127(2004).
RN   [3]
RP   IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS].
RC   TISSUE=Testis;
RX   PubMed=21183079; DOI=10.1016/j.cell.2010.12.001;
RA   Huttlin E.L., Jedrychowski M.P., Elias J.E., Goswami T., Rad R.,
RA   Beausoleil S.A., Villen J., Haas W., Sowa M.E., Gygi S.P.;
RT   "A tissue-specific atlas of mouse protein phosphorylation and expression.";
RL   Cell 143:1174-1189(2010).
CC   -!- FUNCTION: May have an RNA/DNA binding role.
CC   -!- TISSUE SPECIFICITY: Testis.
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DR   EMBL; X99946; CAA68206.1; -; Genomic_DNA.
DR   EMBL; X99796; CAA68129.1; -; mRNA.
DR   EMBL; BC048493; AAH48493.1; -; mRNA.
DR   CCDS; CCDS41090.1; -.
DR   RefSeq; NP_033466.1; NM_009440.3.
DR   RefSeq; XP_006528003.1; XM_006527940.3.
DR   RefSeq; XP_006528004.1; XM_006527941.2.
DR   AlphaFoldDB; P70675; -.
DR   STRING; 10090.ENSMUSP00000033691; -.
DR   PhosphoSitePlus; P70675; -.
DR   PaxDb; P70675; -.
DR   PRIDE; P70675; -.
DR   ProteomicsDB; 298002; -.
DR   Ensembl; ENSMUST00000033691; ENSMUSP00000033691; ENSMUSG00000031329.
DR   GeneID; 22127; -.
DR   KEGG; mmu:22127; -.
DR   UCSC; uc009tzm.2; mouse.
DR   CTD; 22127; -.
DR   MGI; MGI:108118; Tsx.
DR   VEuPathDB; HostDB:ENSMUSG00000031329; -.
DR   eggNOG; ENOG502TCXD; Eukaryota.
DR   GeneTree; ENSGT00520000061207; -.
DR   HOGENOM; CLU_1795880_0_0_1; -.
DR   InParanoid; P70675; -.
DR   OMA; MYMEMFT; -.
DR   OrthoDB; 1482370at2759; -.
DR   TreeFam; TF339784; -.
DR   BioGRID-ORCS; 22127; 1 hit in 72 CRISPR screens.
DR   ChiTaRS; Tsx; mouse.
DR   PRO; PR:P70675; -.
DR   Proteomes; UP000000589; Chromosome X.
DR   RNAct; P70675; protein.
DR   Bgee; ENSMUSG00000031329; Expressed in seminiferous tubule of testis and 26 other tissues.
DR   ExpressionAtlas; P70675; baseline and differential.
DR   Genevisible; P70675; MM.
DR   GO; GO:0005737; C:cytoplasm; IDA:MGI.
DR   GO; GO:0001673; C:male germ cell nucleus; IDA:MGI.
DR   GO; GO:0005634; C:nucleus; IDA:MGI.
DR   GO; GO:0030534; P:adult behavior; IMP:MGI.
DR   GO; GO:0009566; P:fertilization; IMP:MGI.
DR   GO; GO:0008584; P:male gonad development; IMP:MGI.
DR   InterPro; IPR035352; TSX.
DR   Pfam; PF17397; DUF5404; 1.
PE   1: Evidence at protein level;
KW   Reference proteome.
FT   CHAIN           1..144
FT                   /note="Testis-specific protein TSX"
FT                   /id="PRO_0000065672"
FT   REGION          1..21
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          69..99
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          120..144
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   144 AA;  15978 MW;  7979A11C0EAB48EE CRC64;
     MSEKQSPKTS EAECSAMDLP EFEDEENWLF KVLGFQPGPS SALDDDTDDQ ADEPLSAAEF
     LHLQDILQED RVSSTDDEDT CQAGCTEDDE TSHSDRDIDN NVKVITGNIK ASPSMYMEMF
     TDQNPQADQD LEETESDGAM NPTD
 
 
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