TSX_MOUSE
ID TSX_MOUSE Reviewed; 144 AA.
AC P70675;
DT 01-NOV-1997, integrated into UniProtKB/Swiss-Prot.
DT 01-FEB-1997, sequence version 1.
DT 03-AUG-2022, entry version 104.
DE RecName: Full=Testis-specific protein TSX;
GN Name=Tsx;
OS Mus musculus (Mouse).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae;
OC Murinae; Mus; Mus.
OX NCBI_TaxID=10090;
RN [1]
RP NUCLEOTIDE SEQUENCE [GENOMIC DNA / MRNA].
RC STRAIN=129/Sv; TISSUE=Testis;
RX PubMed=8922998; DOI=10.1093/hmg/5.11.1713;
RA Simmler M.-C., Cunningham D.B., Clerc P., Vermat T., Caudron B., Cruaud C.,
RA Pawlak A., Szpirer C., Weissenbach J., Claverie J.-M., Avner P.;
RT "A 94 kb genomic sequence 3' to the murine Xist gene reveals an AT rich
RT region containing a new testis specific gene Tsx.";
RL Hum. Mol. Genet. 5:1713-1726(1996).
RN [2]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC TISSUE=Testis;
RX PubMed=15489334; DOI=10.1101/gr.2596504;
RG The MGC Project Team;
RT "The status, quality, and expansion of the NIH full-length cDNA project:
RT the Mammalian Gene Collection (MGC).";
RL Genome Res. 14:2121-2127(2004).
RN [3]
RP IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS].
RC TISSUE=Testis;
RX PubMed=21183079; DOI=10.1016/j.cell.2010.12.001;
RA Huttlin E.L., Jedrychowski M.P., Elias J.E., Goswami T., Rad R.,
RA Beausoleil S.A., Villen J., Haas W., Sowa M.E., Gygi S.P.;
RT "A tissue-specific atlas of mouse protein phosphorylation and expression.";
RL Cell 143:1174-1189(2010).
CC -!- FUNCTION: May have an RNA/DNA binding role.
CC -!- TISSUE SPECIFICITY: Testis.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; X99946; CAA68206.1; -; Genomic_DNA.
DR EMBL; X99796; CAA68129.1; -; mRNA.
DR EMBL; BC048493; AAH48493.1; -; mRNA.
DR CCDS; CCDS41090.1; -.
DR RefSeq; NP_033466.1; NM_009440.3.
DR RefSeq; XP_006528003.1; XM_006527940.3.
DR RefSeq; XP_006528004.1; XM_006527941.2.
DR AlphaFoldDB; P70675; -.
DR STRING; 10090.ENSMUSP00000033691; -.
DR PhosphoSitePlus; P70675; -.
DR PaxDb; P70675; -.
DR PRIDE; P70675; -.
DR ProteomicsDB; 298002; -.
DR Ensembl; ENSMUST00000033691; ENSMUSP00000033691; ENSMUSG00000031329.
DR GeneID; 22127; -.
DR KEGG; mmu:22127; -.
DR UCSC; uc009tzm.2; mouse.
DR CTD; 22127; -.
DR MGI; MGI:108118; Tsx.
DR VEuPathDB; HostDB:ENSMUSG00000031329; -.
DR eggNOG; ENOG502TCXD; Eukaryota.
DR GeneTree; ENSGT00520000061207; -.
DR HOGENOM; CLU_1795880_0_0_1; -.
DR InParanoid; P70675; -.
DR OMA; MYMEMFT; -.
DR OrthoDB; 1482370at2759; -.
DR TreeFam; TF339784; -.
DR BioGRID-ORCS; 22127; 1 hit in 72 CRISPR screens.
DR ChiTaRS; Tsx; mouse.
DR PRO; PR:P70675; -.
DR Proteomes; UP000000589; Chromosome X.
DR RNAct; P70675; protein.
DR Bgee; ENSMUSG00000031329; Expressed in seminiferous tubule of testis and 26 other tissues.
DR ExpressionAtlas; P70675; baseline and differential.
DR Genevisible; P70675; MM.
DR GO; GO:0005737; C:cytoplasm; IDA:MGI.
DR GO; GO:0001673; C:male germ cell nucleus; IDA:MGI.
DR GO; GO:0005634; C:nucleus; IDA:MGI.
DR GO; GO:0030534; P:adult behavior; IMP:MGI.
DR GO; GO:0009566; P:fertilization; IMP:MGI.
DR GO; GO:0008584; P:male gonad development; IMP:MGI.
DR InterPro; IPR035352; TSX.
DR Pfam; PF17397; DUF5404; 1.
PE 1: Evidence at protein level;
KW Reference proteome.
FT CHAIN 1..144
FT /note="Testis-specific protein TSX"
FT /id="PRO_0000065672"
FT REGION 1..21
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 69..99
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 120..144
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 144 AA; 15978 MW; 7979A11C0EAB48EE CRC64;
MSEKQSPKTS EAECSAMDLP EFEDEENWLF KVLGFQPGPS SALDDDTDDQ ADEPLSAAEF
LHLQDILQED RVSSTDDEDT CQAGCTEDDE TSHSDRDIDN NVKVITGNIK ASPSMYMEMF
TDQNPQADQD LEETESDGAM NPTD