TSY26_HUMAN
ID TSY26_HUMAN Reviewed; 355 AA.
AC Q9H489; Q3MJ63; Q3MJ65;
DT 15-AUG-2003, integrated into UniProtKB/Swiss-Prot.
DT 01-MAR-2001, sequence version 1.
DT 25-MAY-2022, entry version 90.
DE RecName: Full=Putative testis-specific Y-encoded-like protein 3;
DE Short=TSPY-like protein 3;
DE AltName: Full=Testis-specific Y-encoded protein 26 pseudogene;
GN Name=TSPY26P; Synonyms=TSPYL3;
OS Homo sapiens (Human).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae;
OC Homo.
OX NCBI_TaxID=9606;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX PubMed=11780052; DOI=10.1038/414865a;
RA Deloukas P., Matthews L.H., Ashurst J.L., Burton J., Gilbert J.G.R.,
RA Jones M., Stavrides G., Almeida J.P., Babbage A.K., Bagguley C.L.,
RA Bailey J., Barlow K.F., Bates K.N., Beard L.M., Beare D.M., Beasley O.P.,
RA Bird C.P., Blakey S.E., Bridgeman A.M., Brown A.J., Buck D., Burrill W.D.,
RA Butler A.P., Carder C., Carter N.P., Chapman J.C., Clamp M., Clark G.,
RA Clark L.N., Clark S.Y., Clee C.M., Clegg S., Cobley V.E., Collier R.E.,
RA Connor R.E., Corby N.R., Coulson A., Coville G.J., Deadman R., Dhami P.D.,
RA Dunn M., Ellington A.G., Frankland J.A., Fraser A., French L., Garner P.,
RA Grafham D.V., Griffiths C., Griffiths M.N.D., Gwilliam R., Hall R.E.,
RA Hammond S., Harley J.L., Heath P.D., Ho S., Holden J.L., Howden P.J.,
RA Huckle E., Hunt A.R., Hunt S.E., Jekosch K., Johnson C.M., Johnson D.,
RA Kay M.P., Kimberley A.M., King A., Knights A., Laird G.K., Lawlor S.,
RA Lehvaeslaiho M.H., Leversha M.A., Lloyd C., Lloyd D.M., Lovell J.D.,
RA Marsh V.L., Martin S.L., McConnachie L.J., McLay K., McMurray A.A.,
RA Milne S.A., Mistry D., Moore M.J.F., Mullikin J.C., Nickerson T.,
RA Oliver K., Parker A., Patel R., Pearce T.A.V., Peck A.I.,
RA Phillimore B.J.C.T., Prathalingam S.R., Plumb R.W., Ramsay H., Rice C.M.,
RA Ross M.T., Scott C.E., Sehra H.K., Shownkeen R., Sims S., Skuce C.D.,
RA Smith M.L., Soderlund C., Steward C.A., Sulston J.E., Swann R.M.,
RA Sycamore N., Taylor R., Tee L., Thomas D.W., Thorpe A., Tracey A.,
RA Tromans A.C., Vaudin M., Wall M., Wallis J.M., Whitehead S.L.,
RA Whittaker P., Willey D.L., Williams L., Williams S.A., Wilming L.,
RA Wray P.W., Hubbard T., Durbin R.M., Bentley D.R., Beck S., Rogers J.;
RT "The DNA sequence and comparative analysis of human chromosome 20.";
RL Nature 414:865-871(2001).
RN [2]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA], AND VARIANT HIS-246.
RX PubMed=15489334; DOI=10.1101/gr.2596504;
RG The MGC Project Team;
RT "The status, quality, and expansion of the NIH full-length cDNA project:
RT the Mammalian Gene Collection (MGC).";
RL Genome Res. 14:2121-2127(2004).
CC -!- SIMILARITY: Belongs to the nucleosome assembly protein (NAP) family.
CC {ECO:0000305}.
CC -!- CAUTION: Could be the product of a pseudogene. {ECO:0000305}.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; AL121897; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; BC101556; -; NOT_ANNOTATED_CDS; mRNA.
DR EMBL; BC101558; -; NOT_ANNOTATED_CDS; mRNA.
DR AlphaFoldDB; Q9H489; -.
DR SMR; Q9H489; -.
DR BioMuta; HGNC:16256; -.
DR DMDM; 34098714; -.
DR MassIVE; Q9H489; -.
DR PeptideAtlas; Q9H489; -.
DR PRIDE; Q9H489; -.
DR ProteomicsDB; 80795; -.
DR GeneCards; TSPY26P; -.
DR HGNC; HGNC:16256; TSPY26P.
DR neXtProt; NX_Q9H489; -.
DR InParanoid; Q9H489; -.
DR PhylomeDB; Q9H489; -.
DR PathwayCommons; Q9H489; -.
DR Pharos; Q9H489; Tdark.
DR PRO; PR:Q9H489; -.
DR Proteomes; UP000005640; Unplaced.
DR RNAct; Q9H489; protein.
DR GO; GO:0000785; C:chromatin; IBA:GO_Central.
DR GO; GO:0005634; C:nucleus; IBA:GO_Central.
DR GO; GO:0003682; F:chromatin binding; IBA:GO_Central.
DR GO; GO:0042393; F:histone binding; IBA:GO_Central.
DR GO; GO:0006334; P:nucleosome assembly; IEA:InterPro.
DR InterPro; IPR037231; NAP-like_sf.
DR InterPro; IPR002164; NAP_family.
DR PANTHER; PTHR11875; PTHR11875; 1.
DR Pfam; PF00956; NAP; 1.
DR SUPFAM; SSF143113; SSF143113; 1.
PE 5: Uncertain;
KW Reference proteome.
FT CHAIN 1..355
FT /note="Putative testis-specific Y-encoded-like protein 3"
FT /id="PRO_0000185672"
FT REGION 1..131
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 95..131
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT VARIANT 246
FT /note="P -> H (in dbSNP:rs3813922)"
FT /evidence="ECO:0000269|PubMed:15489334"
FT /id="VAR_020256"
SQ SEQUENCE 355 AA; 39573 MW; 20E025E0F15EB7B4 CRC64;
MADKRAGTPE AAARPPPGLA REGDARTVPA ARAREAGGRG SLHPAAGPGT AFPSPGRGEA
ASTATTPSLE NGRVRDEAPE TCGAEGLGTR AGASEKAEDA NKEEGAIFKK EPAEEVEKQQ
EGEEKQEVAA EAQEGPRLLN LGALIVDPLE AIQWEAEAVS AQADRAYLPL ERRFGRMHRL
YLARRSFIIQ NIPGFWVTAF LNHPQLSAMI SPRDEDMLCY LMNLEVRELR HSRTGCKFKF
RFWSNPYFQN KVIVKEYECR ASGRVVSIAT RIRWHWGQEP PALVHRNRDT VRSFFSWFSQ
HSLPEADRVA QIIKDDLWPN PLQYYLLGDR PCRARGGLAR WPTETPSRPY GFQSG