TSYL1_BOVIN
ID TSYL1_BOVIN Reviewed; 432 AA.
AC Q0P5N2;
DT 05-FEB-2008, integrated into UniProtKB/Swiss-Prot.
DT 19-SEP-2006, sequence version 1.
DT 03-AUG-2022, entry version 82.
DE RecName: Full=Testis-specific Y-encoded-like protein 1;
DE Short=TSPY-like protein 1;
GN Name=TSPYL1;
OS Bos taurus (Bovine).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Laurasiatheria; Artiodactyla; Ruminantia; Pecora; Bovidae;
OC Bovinae; Bos.
OX NCBI_TaxID=9913;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC STRAIN=Hereford; TISSUE=Heart ventricle;
RG NIH - Mammalian Gene Collection (MGC) project;
RL Submitted (AUG-2006) to the EMBL/GenBank/DDBJ databases.
CC -!- SUBCELLULAR LOCATION: Nucleus, nucleolus
CC {ECO:0000250|UniProtKB:Q9H0U9}.
CC -!- PTM: Ubiquitinated by the CRL2(APPBP2) complex, which recognizes the
CC Arg-Xaa-Xaa-Gly sequence at the C-terminus, leading to its degradation.
CC {ECO:0000250|UniProtKB:Q9H0U9}.
CC -!- SIMILARITY: Belongs to the nucleosome assembly protein (NAP) family.
CC {ECO:0000305}.
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DR EMBL; BC119828; AAI19829.1; -; mRNA.
DR RefSeq; NP_001069579.1; NM_001076111.2.
DR AlphaFoldDB; Q0P5N2; -.
DR SMR; Q0P5N2; -.
DR STRING; 9913.ENSBTAP00000052314; -.
DR PaxDb; Q0P5N2; -.
DR PRIDE; Q0P5N2; -.
DR Ensembl; ENSBTAT00000014457; ENSBTAP00000052314; ENSBTAG00000010885.
DR GeneID; 538541; -.
DR KEGG; bta:538541; -.
DR CTD; 7259; -.
DR VEuPathDB; HostDB:ENSBTAG00000010885; -.
DR VGNC; VGNC:53811; TSPYL1.
DR eggNOG; KOG1508; Eukaryota.
DR GeneTree; ENSGT00940000162821; -.
DR HOGENOM; CLU_051687_2_0_1; -.
DR InParanoid; Q0P5N2; -.
DR OMA; MDLRMNP; -.
DR OrthoDB; 1191764at2759; -.
DR TreeFam; TF313386; -.
DR Proteomes; UP000009136; Chromosome 9.
DR Bgee; ENSBTAG00000010885; Expressed in adenohypophysis and 105 other tissues.
DR GO; GO:0000785; C:chromatin; IBA:GO_Central.
DR GO; GO:0005730; C:nucleolus; IEA:UniProtKB-SubCell.
DR GO; GO:0005654; C:nucleoplasm; IEA:Ensembl.
DR GO; GO:0005634; C:nucleus; IBA:GO_Central.
DR GO; GO:0003682; F:chromatin binding; IBA:GO_Central.
DR GO; GO:0019899; F:enzyme binding; IEA:Ensembl.
DR GO; GO:0042393; F:histone binding; IBA:GO_Central.
DR GO; GO:0006334; P:nucleosome assembly; IEA:InterPro.
DR InterPro; IPR037231; NAP-like_sf.
DR InterPro; IPR002164; NAP_family.
DR PANTHER; PTHR11875; PTHR11875; 1.
DR Pfam; PF00956; NAP; 1.
DR SUPFAM; SSF143113; SSF143113; 1.
PE 2: Evidence at transcript level;
KW Isopeptide bond; Nucleus; Reference proteome; Ubl conjugation.
FT CHAIN 1..432
FT /note="Testis-specific Y-encoded-like protein 1"
FT /id="PRO_0000317138"
FT REGION 1..31
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 54..110
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 116..135
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT CROSSLNK 160
FT /note="Glycyl lysine isopeptide (Lys-Gly) (interchain with
FT G-Cter in SUMO2)"
FT /evidence="ECO:0000250|UniProtKB:Q9H0U9"
SQ SEQUENCE 432 AA; 48585 MW; 09903C7C24241615 CRC64;
MSGRDGGERT PLLEAHSLTT SDCAAGAPDP SRCLKTEASQ VMAETGEGYF EAVALPPPQL
PEEESAPSTA PSDPGCAGTF QIRAGGDGGY VVPEARLEPA PPPTESLETA SVSLATDDSL
GNGCQPGEPQ GLSREKPLET CGAEKLGSDL MAEAKAEEVK TEEGPVFSVA VDEEVVGKEG
AKEEEGVEQG MEVEERPVGE EIEMVENRVV EEAGHRPLRM DLRMNPLEAI QLELDSVNAQ
ADRAFQQLEH KFGRMRRHYL ERRNYIIQNI PGFWVTAFRN HPQLSPMIRG QDAEMLRYIT
NLEVKELRHP RTGCKFKFFF RRNPYFRNKL IVKEYEVRAS GRVVSLSTPI IWRRGHEPQS
FIRRNQEVVC NFFTWFSDHS LPESDRIAEI IKEDLWPNPL QYYLLREGVR RARRRPIREP
VEIPRPFGFQ SG
