TSYL1_PONAB
ID TSYL1_PONAB Reviewed; 438 AA.
AC Q5R5G8; Q5RA88;
DT 05-FEB-2008, integrated into UniProtKB/Swiss-Prot.
DT 21-DEC-2004, sequence version 1.
DT 25-MAY-2022, entry version 62.
DE RecName: Full=Testis-specific Y-encoded-like protein 1;
DE Short=TSPY-like protein 1;
GN Name=TSPYL1;
OS Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae;
OC Pongo.
OX NCBI_TaxID=9601;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC TISSUE=Brain cortex, and Kidney;
RG The German cDNA consortium;
RL Submitted (NOV-2004) to the EMBL/GenBank/DDBJ databases.
CC -!- SUBCELLULAR LOCATION: Nucleus, nucleolus
CC {ECO:0000250|UniProtKB:Q9H0U9}.
CC -!- PTM: Ubiquitinated by the CRL2(APPBP2) complex, which recognizes the
CC Arg-Xaa-Xaa-Gly sequence at the C-terminus, leading to its degradation.
CC {ECO:0000250|UniProtKB:Q9H0U9}.
CC -!- SIMILARITY: Belongs to the nucleosome assembly protein (NAP) family.
CC {ECO:0000305}.
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DR EMBL; CR859130; CAH91322.1; -; mRNA.
DR EMBL; CR860891; CAH92998.1; -; mRNA.
DR RefSeq; NP_001127617.1; NM_001134145.1.
DR AlphaFoldDB; Q5R5G8; -.
DR SMR; Q5R5G8; -.
DR STRING; 9601.ENSPPYP00000018972; -.
DR GeneID; 100174696; -.
DR KEGG; pon:100174696; -.
DR CTD; 7259; -.
DR eggNOG; KOG1508; Eukaryota.
DR InParanoid; Q5R5G8; -.
DR OrthoDB; 1191764at2759; -.
DR Proteomes; UP000001595; Unplaced.
DR GO; GO:0005730; C:nucleolus; IEA:UniProtKB-SubCell.
DR GO; GO:0006334; P:nucleosome assembly; IEA:InterPro.
DR InterPro; IPR037231; NAP-like_sf.
DR InterPro; IPR002164; NAP_family.
DR PANTHER; PTHR11875; PTHR11875; 1.
DR Pfam; PF00956; NAP; 1.
DR SUPFAM; SSF143113; SSF143113; 1.
PE 2: Evidence at transcript level;
KW Isopeptide bond; Nucleus; Reference proteome; Ubl conjugation.
FT CHAIN 1..438
FT /note="Testis-specific Y-encoded-like protein 1"
FT /id="PRO_0000317136"
FT REGION 41..82
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT CROSSLNK 156
FT /note="Glycyl lysine isopeptide (Lys-Gly) (interchain with
FT G-Cter in SUMO2)"
FT /evidence="ECO:0000250|UniProtKB:Q9H0U9"
FT CONFLICT 29
FT /note="G -> D (in Ref. 1; CAH91322)"
FT /evidence="ECO:0000305"
SQ SEQUENCE 438 AA; 49292 MW; F885B1D3D455F39B CRC64;
MSGLDGVKRT PPLQTHSIII SDQVPSDQGA HQYLRLRAQS EATQVMAEPG EGGSETVALP
FPPPSEEGGV PQDPAGRGGT PQFRVVGGRG HVAIKAGQEE GQPPAEGLAA ASVVMAADHS
LKKGVQGGEK ALEICGAERS ASELTAGAEA EAEEVKTGKC ATISAAVAER ESAEVMVKEG
LAEKEVVEEQ MEVEEQPPEG EEIEVAEEDR LEEEAREEEG PWPLHEALRM DPLEAIQLEL
DTVNAQADRA FQQLEHKFGR MRRHYLERRN YIIQNIPGFW MTAFRNHPQL SAMIRGQDAE
MLRYITNLEV KELRHPRTGC KFKFFFRRNP YFRNKLIVKE YEVRSSGRVV SLSTPIIWRR
GHEPQSFIRR NQDLICSFFT WFSDHSLPES DKIAEIIKED LWPNPLQYYL LREGVRRARR
RPLREPVEIP RPFGFQSG