ID   TTBK6_CAEEL             Reviewed;         290 AA.
AC   Q09503;
DT   01-NOV-1995, integrated into UniProtKB/Swiss-Prot.
DT   02-AUG-2002, sequence version 2.
DT   03-AUG-2022, entry version 124.
DE   RecName: Full=Inactive tau-tubulin kinase ttbk-6 {ECO:0000305};
GN   Name=ttbk-6 {ECO:0000312|WormBase:C45G9.1};
GN   ORFNames=C45G9.1 {ECO:0000312|WormBase:C45G9.1};
OS   Caenorhabditis elegans.
OC   Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida;
OC   Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae;
OC   Caenorhabditis.
OX   NCBI_TaxID=6239;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=Bristol N2;
RX   PubMed=9851916; DOI=10.1126/science.282.5396.2012;
RG   The C. elegans sequencing consortium;
RT   "Genome sequence of the nematode C. elegans: a platform for investigating
RT   biology.";
RL   Science 282:2012-2018(1998).
CC   -!- DOMAIN: The protein kinase domain is predicted to be catalytically
CC       inactive. {ECO:0000255|PROSITE-ProRule:PRU00159}.
CC   -!- SIMILARITY: Belongs to the protein kinase superfamily. CK1 Ser/Thr
CC       protein kinase family. {ECO:0000305}.
CC   -!- CAUTION: Although it belongs to the protein kinase family, lacks the
CC       active site Asp residue which has been changed to Asn so is unlikely to
CC       be catalytically active. {ECO:0000305}.
CC   ---------------------------------------------------------------------------
CC   Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC   Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC   ---------------------------------------------------------------------------
DR   EMBL; BX284603; CCD67390.1; -; Genomic_DNA.
DR   PIR; C88449; C88449.
DR   RefSeq; NP_498080.1; NM_065679.1.
DR   AlphaFoldDB; Q09503; -.
DR   SMR; Q09503; -.
DR   STRING; 6239.C45G9.1; -.
DR   PaxDb; Q09503; -.
DR   EnsemblMetazoa; C45G9.1.1; C45G9.1.1; WBGene00016673.
DR   GeneID; 183478; -.
DR   KEGG; cel:CELE_C45G9.1; -.
DR   UCSC; C45G9.1; c. elegans.
DR   CTD; 183478; -.
DR   WormBase; C45G9.1; CE24851; WBGene00016673; ttbk-6.
DR   eggNOG; KOG1164; Eukaryota.
DR   GeneTree; ENSGT00970000196711; -.
DR   HOGENOM; CLU_019279_2_5_1; -.
DR   InParanoid; Q09503; -.
DR   OMA; RYHAREN; -.
DR   OrthoDB; 919785at2759; -.
DR   PhylomeDB; Q09503; -.
DR   PRO; PR:Q09503; -.
DR   Proteomes; UP000001940; Chromosome III.
DR   GO; GO:0005737; C:cytoplasm; IBA:GO_Central.
DR   GO; GO:0005634; C:nucleus; IBA:GO_Central.
DR   GO; GO:0005524; F:ATP binding; IEA:InterPro.
DR   GO; GO:0004674; F:protein serine/threonine kinase activity; IBA:GO_Central.
DR   GO; GO:0018105; P:peptidyl-serine phosphorylation; IBA:GO_Central.
DR   GO; GO:0007165; P:signal transduction; IBA:GO_Central.
DR   InterPro; IPR011009; Kinase-like_dom_sf.
DR   InterPro; IPR000719; Prot_kinase_dom.
DR   Pfam; PF00069; Pkinase; 1.
DR   SMART; SM00220; S_TKc; 1.
DR   SUPFAM; SSF56112; SSF56112; 1.
DR   PROSITE; PS50011; PROTEIN_KINASE_DOM; 1.
PE   3: Inferred from homology;
KW   Reference proteome.
FT   CHAIN           1..290
FT                   /note="Inactive tau-tubulin kinase ttbk-6"
FT                   /id="PRO_0000086838"
FT   DOMAIN          1..240
FT                   /note="Protein kinase"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00159"
FT   REGION          244..263
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          268..290
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   290 AA;  33803 MW;  6595F28BAABD6180 CRC64;
     MEDHVLKKLN ANGPAPHIPN LNLYGKKMNF SYMVMTLLGR NLQDLESTNF VVNKGFSRGT
     WSRVGIQWVY ALKYVHYNGF IHRNVNTQNL FLGNEKDSER AKIIHILDFG LGRPFARYHA
     RENKWIVRIA RHSAEFRGSF RYASPNVHLR KEQGRVDDVW SLPYVIIELN GGKALPWQTD
     YRRGRVEQMK LNLTPKDVMS DMPACMDKLM PHLASLNYYQ RPDDHMIFKC FWQVMENEKI
     TPSSKFDWEN EEPDMSVPPA AWENPDGRYF QSNPLEINGP PTPAEVDFVL