ID   TTC27_PONAB             Reviewed;         843 AA.
AC   Q5RBW9;
DT   10-JUL-2007, integrated into UniProtKB/Swiss-Prot.
DT   21-DEC-2004, sequence version 1.
DT   25-MAY-2022, entry version 71.
DE   RecName: Full=Tetratricopeptide repeat protein 27;
DE            Short=TPR repeat protein 27;
GN   Name=TTC27;
OS   Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC   Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae;
OC   Pongo.
OX   NCBI_TaxID=9601;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC   TISSUE=Kidney;
RG   The German cDNA consortium;
RL   Submitted (NOV-2004) to the EMBL/GenBank/DDBJ databases.
CC   -!- SIMILARITY: Belongs to the TTC27 family. {ECO:0000305}.
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DR   EMBL; CR858513; CAH90741.1; -; mRNA.
DR   RefSeq; NP_001127328.1; NM_001133856.1.
DR   AlphaFoldDB; Q5RBW9; -.
DR   SMR; Q5RBW9; -.
DR   STRING; 9601.ENSPPYP00000013964; -.
DR   GeneID; 100174389; -.
DR   KEGG; pon:100174389; -.
DR   CTD; 55622; -.
DR   eggNOG; KOG1128; Eukaryota.
DR   InParanoid; Q5RBW9; -.
DR   OrthoDB; 1039489at2759; -.
DR   Proteomes; UP000001595; Unplaced.
DR   Gene3D; 1.25.40.10; -; 1.
DR   InterPro; IPR011990; TPR-like_helical_dom_sf.
DR   InterPro; IPR013105; TPR_2.
DR   InterPro; IPR019734; TPR_repeat.
DR   InterPro; IPR044244; TTC27/Emw1.
DR   PANTHER; PTHR16193; PTHR16193; 1.
DR   Pfam; PF07719; TPR_2; 1.
DR   SMART; SM00028; TPR; 4.
DR   SUPFAM; SSF48452; SSF48452; 1.
DR   PROSITE; PS50005; TPR; 4.
DR   PROSITE; PS50293; TPR_REGION; 1.
PE   2: Evidence at transcript level;
KW   Reference proteome; Repeat; TPR repeat.
FT   CHAIN           1..843
FT                   /note="Tetratricopeptide repeat protein 27"
FT                   /id="PRO_0000295098"
FT   REPEAT          453..486
FT                   /note="TPR 1"
FT   REPEAT          492..525
FT                   /note="TPR 2"
FT   REPEAT          527..560
FT                   /note="TPR 3"
FT   REPEAT          561..594
FT                   /note="TPR 4"
FT   REPEAT          596..628
FT                   /note="TPR 5"
FT   REPEAT          629..662
FT                   /note="TPR 6"
SQ   SEQUENCE   843 AA;  96661 MW;  73C137F739D9EAAC CRC64;
     MWTPELAILR GFPTEAERQQ WKQEGVVGSE SGSFLQLLLE GNHEAIFLNS MTQNIFSSTT
     TAEEKIDSYL EKQVVTFLDY STDLDTTERQ RLIFLLGVSS LQLFVQSNWT GPPVDLHPQD
     FLSSVLFQQF SEVKGLDAFV LSLLILDGES IYSLTSKPIL LLLARIILVN VRHKLTAIQS
     LPWWTLRCVN IHQHLLEERS PLLFTLAENC IDQVMKLQNL FVDDSGRYLA IQFHLECAYV
     FLYYYEYRKA KDQLDIAKDI SQLQTDLTGA LGKRTRFQEN YVAQLILDVR REGDVLSNCE
     FTPAPTPQEH LTKNLELNDD TILNDIKLAD CEQFQMPDLC AEELAIILGI CTNFQKNNPV
     HTLTEEELLA FTSCLLSQPK FWAIQTSALI LRTKLEKGST RRVERAMRQT QALADQFEDK
     TTSVLERLKI FYCCQVPPHW AIQRQLASLL FELGCTSSAL QIFEKLEMWE DVVICYERAG
     QHGKAEEILR QELEKKQTPS LYCLLGDVLG DHSCYDKAWE LSRYRSARAQ RSKALLHLRN
     KEFQECVECF ERSVKINPMQ LGVWFSLGCA YLALEDYQGS AKAFQRCVTL EPDNAEAWNN
     LSTSYIRLKQ KVKAFRTLQE ALKCNYEHWQ IWENYILTST DVGEFSEAIK AYHRLLDLRD
     KYKDVQVLKI LLRAVIDGMT DRSGDVATGL KGKLQELFGR VTSRVTNDGE IWRLYAHVYG
     NGQSEKPDEN EKAFQCLSKA YKCDTQSNCW EKDITSFKEV VQRALGLAHV AIKCSKNKSS
     PQEAVQMLSS VRLNLRGLLS KAKQLFTDVA TGEMSRELAD DITAMDTLVT ELQDLSNQFR
     NQY