ID   TTC29_RAT               Reviewed;         471 AA.
AC   Q6AYP3;
DT   10-JUL-2007, integrated into UniProtKB/Swiss-Prot.
DT   13-SEP-2004, sequence version 1.
DT   03-AUG-2022, entry version 111.
DE   RecName: Full=Tetratricopeptide repeat protein 29;
DE            Short=TPR repeat protein 29;
GN   Name=Ttc29;
OS   Rattus norvegicus (Rat).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC   Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae;
OC   Murinae; Rattus.
OX   NCBI_TaxID=10116;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC   TISSUE=Testis;
RX   PubMed=15489334; DOI=10.1101/gr.2596504;
RG   The MGC Project Team;
RT   "The status, quality, and expansion of the NIH full-length cDNA project:
RT   the Mammalian Gene Collection (MGC).";
RL   Genome Res. 14:2121-2127(2004).
RN   [2]
RP   IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS].
RX   PubMed=22673903; DOI=10.1038/ncomms1871;
RA   Lundby A., Secher A., Lage K., Nordsborg N.B., Dmytriyev A., Lundby C.,
RA   Olsen J.V.;
RT   "Quantitative maps of protein phosphorylation sites across 14 different rat
RT   organs and tissues.";
RL   Nat. Commun. 3:876-876(2012).
CC   -!- FUNCTION: Axonemal protein which is implicated in axonemal and/or peri-
CC       axonemal structures assembly and regulates flagella assembly and
CC       beating and therefore sperm motility. {ECO:0000250|UniProtKB:Q8NA56}.
CC   -!- SUBCELLULAR LOCATION: Cytoplasm, cytoskeleton, flagellum axoneme
CC       {ECO:0000250|UniProtKB:Q80VM3}.
CC   -!- DOMAIN: The TPR repeats are required for proper localization into the
CC       axoneme and proper function in flagella beating and motility.
CC       {ECO:0000250|UniProtKB:Q8NA56}.
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DR   EMBL; BC078968; AAH78968.1; -; mRNA.
DR   RefSeq; NP_001013912.1; NM_001013890.1.
DR   RefSeq; XP_017456705.1; XM_017601216.1.
DR   AlphaFoldDB; Q6AYP3; -.
DR   SMR; Q6AYP3; -.
DR   STRING; 10116.ENSRNOP00000016558; -.
DR   iPTMnet; Q6AYP3; -.
DR   PhosphoSitePlus; Q6AYP3; -.
DR   PaxDb; Q6AYP3; -.
DR   PRIDE; Q6AYP3; -.
DR   Ensembl; ENSRNOT00000016558; ENSRNOP00000016558; ENSRNOG00000012342.
DR   GeneID; 291944; -.
DR   KEGG; rno:291944; -.
DR   UCSC; RGD:1589777; rat.
DR   CTD; 83894; -.
DR   RGD; 1589777; Ttc29.
DR   eggNOG; ENOG502QQ2U; Eukaryota.
DR   GeneTree; ENSGT00390000008611; -.
DR   HOGENOM; CLU_041196_1_0_1; -.
DR   InParanoid; Q6AYP3; -.
DR   OrthoDB; 732310at2759; -.
DR   PhylomeDB; Q6AYP3; -.
DR   TreeFam; TF328344; -.
DR   PRO; PR:Q6AYP3; -.
DR   Proteomes; UP000002494; Chromosome 19.
DR   Bgee; ENSRNOG00000012342; Expressed in testis and 1 other tissue.
DR   ExpressionAtlas; Q6AYP3; baseline.
DR   GO; GO:0005929; C:cilium; IBA:GO_Central.
DR   GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-KW.
DR   GO; GO:0005856; C:cytoskeleton; IEA:UniProtKB-KW.
DR   GO; GO:0036126; C:sperm flagellum; ISS:UniProtKB.
DR   GO; GO:0003341; P:cilium movement; ISS:UniProtKB.
DR   GO; GO:0044782; P:cilium organization; ISO:RGD.
DR   Gene3D; 1.25.40.10; -; 2.
DR   InterPro; IPR011990; TPR-like_helical_dom_sf.
DR   InterPro; IPR019734; TPR_repeat.
DR   SMART; SM00028; TPR; 4.
DR   SUPFAM; SSF48452; SSF48452; 1.
DR   PROSITE; PS50005; TPR; 5.
DR   PROSITE; PS50293; TPR_REGION; 2.
PE   1: Evidence at protein level;
KW   Cell projection; Cilium; Cytoplasm; Cytoskeleton; Flagellum;
KW   Reference proteome; Repeat; TPR repeat.
FT   CHAIN           1..471
FT                   /note="Tetratricopeptide repeat protein 29"
FT                   /id="PRO_0000294438"
FT   REPEAT          92..131
FT                   /note="TPR 1"
FT                   /evidence="ECO:0000250|UniProtKB:Q8NA56"
FT   REPEAT          136..173
FT                   /note="TPR 2"
FT                   /evidence="ECO:0000250|UniProtKB:Q8NA56"
FT   REPEAT          182..215
FT                   /note="TPR 1"
FT                   /evidence="ECO:0000255"
FT   REPEAT          234..267
FT                   /note="TPR 2"
FT                   /evidence="ECO:0000255"
FT   REPEAT          274..307
FT                   /note="TPR 3"
FT                   /evidence="ECO:0000255"
FT   REPEAT          314..347
FT                   /note="TPR 4"
FT                   /evidence="ECO:0000255"
FT   REPEAT          354..387
FT                   /note="TPR 5"
FT                   /evidence="ECO:0000255"
SQ   SEQUENCE   471 AA;  54476 MW;  9D9CAE0C485ABD35 CRC64;
     MATFPPLSMT RTKLAVLARQ KLPCSSKSIP RAQLIKEKDD IDYYLEQNIK GLSKEEVAAH
     RNSYKKSICV DMLRDGFHKS FTELFSLMEQ WDKLREAAQA RSLFWLQRPL EDQPDKLDNF
     YHYLTKAEAA ERKGYYEEVY NNLYALACYF DNSEDKWVRN HFYERCFKIA QLIKVDGGKK
     EAEAEAHMGL LYEEEGELLK AAEHYEAFHE LTQGRLWKDA TGQFLNLIAC ESLVRTYRLL
     SDRMLQNRDY KQAIKILIKA SEIAREGNDR SMEGEASYYL GLAHLASGEY ETALSVLDRY
     SEISTSLDDE LSLGRAYEAM AKVLQSQGEM TEAIKYLEKF VVIARNNFKS LDVIQACTML
     GDIYNEKGQY NKASDYFQQA FSTAMEVTKT TLMDETKVHY GIARAHQMML TMNGYIESAD
     MNSLNCLLSW KETRTQVEYD PILGEARKAT EDNIYQFPDA QEETRRSPEN Q