TTC32_MOUSE
ID TTC32_MOUSE Reviewed; 148 AA.
AC Q9DAC7;
DT 12-DEC-2006, integrated into UniProtKB/Swiss-Prot.
DT 01-JUN-2001, sequence version 1.
DT 03-AUG-2022, entry version 129.
DE RecName: Full=Tetratricopeptide repeat protein 32;
DE Short=TPR repeat protein 32;
GN Name=Ttc32;
OS Mus musculus (Mouse).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae;
OC Murinae; Mus; Mus.
OX NCBI_TaxID=10090;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC STRAIN=C57BL/6J; TISSUE=Medulla oblongata, and Testis;
RX PubMed=16141072; DOI=10.1126/science.1112014;
RA Carninci P., Kasukawa T., Katayama S., Gough J., Frith M.C., Maeda N.,
RA Oyama R., Ravasi T., Lenhard B., Wells C., Kodzius R., Shimokawa K.,
RA Bajic V.B., Brenner S.E., Batalov S., Forrest A.R., Zavolan M., Davis M.J.,
RA Wilming L.G., Aidinis V., Allen J.E., Ambesi-Impiombato A., Apweiler R.,
RA Aturaliya R.N., Bailey T.L., Bansal M., Baxter L., Beisel K.W., Bersano T.,
RA Bono H., Chalk A.M., Chiu K.P., Choudhary V., Christoffels A.,
RA Clutterbuck D.R., Crowe M.L., Dalla E., Dalrymple B.P., de Bono B.,
RA Della Gatta G., di Bernardo D., Down T., Engstrom P., Fagiolini M.,
RA Faulkner G., Fletcher C.F., Fukushima T., Furuno M., Futaki S.,
RA Gariboldi M., Georgii-Hemming P., Gingeras T.R., Gojobori T., Green R.E.,
RA Gustincich S., Harbers M., Hayashi Y., Hensch T.K., Hirokawa N., Hill D.,
RA Huminiecki L., Iacono M., Ikeo K., Iwama A., Ishikawa T., Jakt M.,
RA Kanapin A., Katoh M., Kawasawa Y., Kelso J., Kitamura H., Kitano H.,
RA Kollias G., Krishnan S.P., Kruger A., Kummerfeld S.K., Kurochkin I.V.,
RA Lareau L.F., Lazarevic D., Lipovich L., Liu J., Liuni S., McWilliam S.,
RA Madan Babu M., Madera M., Marchionni L., Matsuda H., Matsuzawa S., Miki H.,
RA Mignone F., Miyake S., Morris K., Mottagui-Tabar S., Mulder N., Nakano N.,
RA Nakauchi H., Ng P., Nilsson R., Nishiguchi S., Nishikawa S., Nori F.,
RA Ohara O., Okazaki Y., Orlando V., Pang K.C., Pavan W.J., Pavesi G.,
RA Pesole G., Petrovsky N., Piazza S., Reed J., Reid J.F., Ring B.Z.,
RA Ringwald M., Rost B., Ruan Y., Salzberg S.L., Sandelin A., Schneider C.,
RA Schoenbach C., Sekiguchi K., Semple C.A., Seno S., Sessa L., Sheng Y.,
RA Shibata Y., Shimada H., Shimada K., Silva D., Sinclair B., Sperling S.,
RA Stupka E., Sugiura K., Sultana R., Takenaka Y., Taki K., Tammoja K.,
RA Tan S.L., Tang S., Taylor M.S., Tegner J., Teichmann S.A., Ueda H.R.,
RA van Nimwegen E., Verardo R., Wei C.L., Yagi K., Yamanishi H.,
RA Zabarovsky E., Zhu S., Zimmer A., Hide W., Bult C., Grimmond S.M.,
RA Teasdale R.D., Liu E.T., Brusic V., Quackenbush J., Wahlestedt C.,
RA Mattick J.S., Hume D.A., Kai C., Sasaki D., Tomaru Y., Fukuda S.,
RA Kanamori-Katayama M., Suzuki M., Aoki J., Arakawa T., Iida J., Imamura K.,
RA Itoh M., Kato T., Kawaji H., Kawagashira N., Kawashima T., Kojima M.,
RA Kondo S., Konno H., Nakano K., Ninomiya N., Nishio T., Okada M., Plessy C.,
RA Shibata K., Shiraki T., Suzuki S., Tagami M., Waki K., Watahiki A.,
RA Okamura-Oho Y., Suzuki H., Kawai J., Hayashizaki Y.;
RT "The transcriptional landscape of the mammalian genome.";
RL Science 309:1559-1563(2005).
RN [2]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC TISSUE=Brain;
RX PubMed=15489334; DOI=10.1101/gr.2596504;
RG The MGC Project Team;
RT "The status, quality, and expansion of the NIH full-length cDNA project:
RT the Mammalian Gene Collection (MGC).";
RL Genome Res. 14:2121-2127(2004).
RN [3]
RP IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS].
RC TISSUE=Liver;
RX PubMed=21183079; DOI=10.1016/j.cell.2010.12.001;
RA Huttlin E.L., Jedrychowski M.P., Elias J.E., Goswami T., Rad R.,
RA Beausoleil S.A., Villen J., Haas W., Sowa M.E., Gygi S.P.;
RT "A tissue-specific atlas of mouse protein phosphorylation and expression.";
RL Cell 143:1174-1189(2010).
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DR EMBL; AK005950; BAB24334.1; -; mRNA.
DR EMBL; AK078146; BAC37147.1; -; mRNA.
DR EMBL; BC119273; AAI19274.1; -; mRNA.
DR CCDS; CCDS25808.1; -.
DR RefSeq; NP_083597.1; NM_029321.2.
DR AlphaFoldDB; Q9DAC7; -.
DR SMR; Q9DAC7; -.
DR STRING; 10090.ENSMUSP00000082891; -.
DR PhosphoSitePlus; Q9DAC7; -.
DR EPD; Q9DAC7; -.
DR MaxQB; Q9DAC7; -.
DR PaxDb; Q9DAC7; -.
DR PRIDE; Q9DAC7; -.
DR ProteomicsDB; 298328; -.
DR Antibodypedia; 27107; 241 antibodies from 20 providers.
DR DNASU; 75516; -.
DR Ensembl; ENSMUST00000085741; ENSMUSP00000082891; ENSMUSG00000066637.
DR GeneID; 75516; -.
DR KEGG; mmu:75516; -.
DR UCSC; uc007nal.1; mouse.
DR CTD; 130502; -.
DR MGI; MGI:1922766; Ttc32.
DR VEuPathDB; HostDB:ENSMUSG00000066637; -.
DR eggNOG; KOG1124; Eukaryota.
DR GeneTree; ENSGT00390000011905; -.
DR HOGENOM; CLU_151642_0_0_1; -.
DR InParanoid; Q9DAC7; -.
DR OMA; IHYRLGF; -.
DR OrthoDB; 1591993at2759; -.
DR PhylomeDB; Q9DAC7; -.
DR BioGRID-ORCS; 75516; 4 hits in 73 CRISPR screens.
DR PRO; PR:Q9DAC7; -.
DR Proteomes; UP000000589; Chromosome 12.
DR RNAct; Q9DAC7; protein.
DR Bgee; ENSMUSG00000066637; Expressed in intercostal muscle and 207 other tissues.
DR ExpressionAtlas; Q9DAC7; baseline and differential.
DR Genevisible; Q9DAC7; MM.
DR Gene3D; 1.25.40.10; -; 1.
DR InterPro; IPR011990; TPR-like_helical_dom_sf.
DR InterPro; IPR013105; TPR_2.
DR InterPro; IPR019734; TPR_repeat.
DR Pfam; PF07719; TPR_2; 1.
DR SMART; SM00028; TPR; 2.
DR SUPFAM; SSF48452; SSF48452; 1.
DR PROSITE; PS50005; TPR; 2.
DR PROSITE; PS50293; TPR_REGION; 1.
PE 1: Evidence at protein level;
KW Reference proteome; Repeat; TPR repeat.
FT CHAIN 1..148
FT /note="Tetratricopeptide repeat protein 32"
FT /id="PRO_0000263101"
FT REPEAT 12..45
FT /note="TPR 1"
FT REPEAT 55..88
FT /note="TPR 2"
FT REPEAT 89..122
FT /note="TPR 3"
SQ SEQUENCE 148 AA; 16796 MW; 80BC6D79AC9CDEC9 CRC64;
MALRPGREGG ESSAALATAQ ARFSRGEFAE ARELYSAFIG QCARHGSKCS PEDLATAYNN
RGQTKYFSVD FYEAMDDYTS AIEILPSFEV PYYNRGLIRY RLGYFDEALE DFKKALDLNP
GFQDAVLSLK QTILDKEEKQ RRNAEKSY