ID   TTC33_DANRE             Reviewed;         268 AA.
AC   Q6DI40;
DT   15-MAY-2007, integrated into UniProtKB/Swiss-Prot.
DT   16-AUG-2004, sequence version 1.
DT   03-AUG-2022, entry version 104.
DE   RecName: Full=Tetratricopeptide repeat protein 33;
DE            Short=TPR repeat protein 33;
GN   Name=ttc33; ORFNames=si:dkey-204l11.4, zgc:86619;
OS   Danio rerio (Zebrafish) (Brachydanio rerio).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC   Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes;
OC   Danionidae; Danioninae; Danio.
OX   NCBI_TaxID=7955;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=Tuebingen;
RX   PubMed=23594743; DOI=10.1038/nature12111;
RA   Howe K., Clark M.D., Torroja C.F., Torrance J., Berthelot C., Muffato M.,
RA   Collins J.E., Humphray S., McLaren K., Matthews L., McLaren S., Sealy I.,
RA   Caccamo M., Churcher C., Scott C., Barrett J.C., Koch R., Rauch G.J.,
RA   White S., Chow W., Kilian B., Quintais L.T., Guerra-Assuncao J.A., Zhou Y.,
RA   Gu Y., Yen J., Vogel J.H., Eyre T., Redmond S., Banerjee R., Chi J., Fu B.,
RA   Langley E., Maguire S.F., Laird G.K., Lloyd D., Kenyon E., Donaldson S.,
RA   Sehra H., Almeida-King J., Loveland J., Trevanion S., Jones M., Quail M.,
RA   Willey D., Hunt A., Burton J., Sims S., McLay K., Plumb B., Davis J.,
RA   Clee C., Oliver K., Clark R., Riddle C., Elliot D., Threadgold G.,
RA   Harden G., Ware D., Begum S., Mortimore B., Kerry G., Heath P.,
RA   Phillimore B., Tracey A., Corby N., Dunn M., Johnson C., Wood J., Clark S.,
RA   Pelan S., Griffiths G., Smith M., Glithero R., Howden P., Barker N.,
RA   Lloyd C., Stevens C., Harley J., Holt K., Panagiotidis G., Lovell J.,
RA   Beasley H., Henderson C., Gordon D., Auger K., Wright D., Collins J.,
RA   Raisen C., Dyer L., Leung K., Robertson L., Ambridge K., Leongamornlert D.,
RA   McGuire S., Gilderthorp R., Griffiths C., Manthravadi D., Nichol S.,
RA   Barker G., Whitehead S., Kay M., Brown J., Murnane C., Gray E.,
RA   Humphries M., Sycamore N., Barker D., Saunders D., Wallis J., Babbage A.,
RA   Hammond S., Mashreghi-Mohammadi M., Barr L., Martin S., Wray P.,
RA   Ellington A., Matthews N., Ellwood M., Woodmansey R., Clark G., Cooper J.,
RA   Tromans A., Grafham D., Skuce C., Pandian R., Andrews R., Harrison E.,
RA   Kimberley A., Garnett J., Fosker N., Hall R., Garner P., Kelly D., Bird C.,
RA   Palmer S., Gehring I., Berger A., Dooley C.M., Ersan-Urun Z., Eser C.,
RA   Geiger H., Geisler M., Karotki L., Kirn A., Konantz J., Konantz M.,
RA   Oberlander M., Rudolph-Geiger S., Teucke M., Lanz C., Raddatz G.,
RA   Osoegawa K., Zhu B., Rapp A., Widaa S., Langford C., Yang F.,
RA   Schuster S.C., Carter N.P., Harrow J., Ning Z., Herrero J., Searle S.M.,
RA   Enright A., Geisler R., Plasterk R.H., Lee C., Westerfield M.,
RA   de Jong P.J., Zon L.I., Postlethwait J.H., Nusslein-Volhard C.,
RA   Hubbard T.J., Roest Crollius H., Rogers J., Stemple D.L.;
RT   "The zebrafish reference genome sequence and its relationship to the human
RT   genome.";
RL   Nature 496:498-503(2013).
RN   [2]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC   TISSUE=Embryo;
RG   NIH - Zebrafish Gene Collection (ZGC) project;
RL   Submitted (JUL-2004) to the EMBL/GenBank/DDBJ databases.
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DR   EMBL; CR762390; CAM56588.1; -; Genomic_DNA.
DR   EMBL; BC075750; AAH75750.1; -; mRNA.
DR   RefSeq; NP_001002722.1; NM_001002722.1.
DR   AlphaFoldDB; Q6DI40; -.
DR   SMR; Q6DI40; -.
DR   STRING; 7955.ENSDARP00000051311; -.
DR   PaxDb; Q6DI40; -.
DR   Ensembl; ENSDART00000051312; ENSDARP00000051311; ENSDARG00000035406.
DR   Ensembl; ENSDART00000192784; ENSDARP00000156436; ENSDARG00000111770.
DR   GeneID; 436995; -.
DR   KEGG; dre:436995; -.
DR   CTD; 23548; -.
DR   ZFIN; ZDB-GENE-040718-480; ttc33.
DR   eggNOG; KOG0553; Eukaryota.
DR   GeneTree; ENSGT00390000017462; -.
DR   HOGENOM; CLU_1061581_0_0_1; -.
DR   InParanoid; Q6DI40; -.
DR   OMA; DDGNWLH; -.
DR   OrthoDB; 1579428at2759; -.
DR   PhylomeDB; Q6DI40; -.
DR   TreeFam; TF332142; -.
DR   PRO; PR:Q6DI40; -.
DR   Proteomes; UP000000437; Genome assembly.
DR   Proteomes; UP000814640; Chromosome 5.
DR   Bgee; ENSDARG00000035406; Expressed in muscle tissue and 20 other tissues.
DR   Gene3D; 1.25.40.10; -; 1.
DR   InterPro; IPR011990; TPR-like_helical_dom_sf.
DR   InterPro; IPR019734; TPR_repeat.
DR   SMART; SM00028; TPR; 2.
DR   SUPFAM; SSF48452; SSF48452; 1.
DR   PROSITE; PS50005; TPR; 2.
DR   PROSITE; PS50293; TPR_REGION; 1.
PE   2: Evidence at transcript level;
KW   Reference proteome; Repeat; TPR repeat.
FT   CHAIN           1..268
FT                   /note="Tetratricopeptide repeat protein 33"
FT                   /id="PRO_0000287517"
FT   REPEAT          60..93
FT                   /note="TPR 1"
FT   REPEAT          94..127
FT                   /note="TPR 2"
FT   REPEAT          128..161
FT                   /note="TPR 3"
FT   REGION          14..34
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          249..268
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        251..268
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   268 AA;  30758 MW;  855C33F7FF52DFD2 CRC64;
     MASFGWKRKV GERVSKQTVQ QFEQDSEQAD EDEVEREGVD WLHVIKRKRE VLLEDCAAKS
     KRLKEEGALL AEQDRNWEAL KKWDEAVQLT PEDAVLYEMK SQVLITLGEV FLAVQSAEMA
     TRLRPIWWEA WQTLGRAQLS LGEVELAVRS FQVALHLHPS ERPLWEEDLN WALKLRENQQ
     SLREKASQVD EARRLLVEAP ELKGDYDFES DEVIEACSAM ADRQKQYEDL KKKAVVVDAH
     GEAKEMLVEG DDNPTSSSQS VLIKARGL