TTC36_DROME
ID TTC36_DROME Reviewed; 185 AA.
AC Q9VU70; C5WLP7;
DT 29-APR-2008, integrated into UniProtKB/Swiss-Prot.
DT 01-MAY-2000, sequence version 1.
DT 03-AUG-2022, entry version 141.
DE RecName: Full=Tetratricopeptide repeat protein 36 homolog;
DE Short=TPR repeat protein 36 homolog;
GN ORFNames=CG14105;
OS Drosophila melanogaster (Fruit fly).
OC Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota;
OC Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea;
OC Drosophilidae; Drosophila; Sophophora.
OX NCBI_TaxID=7227;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Berkeley;
RX PubMed=10731132; DOI=10.1126/science.287.5461.2185;
RA Adams M.D., Celniker S.E., Holt R.A., Evans C.A., Gocayne J.D.,
RA Amanatides P.G., Scherer S.E., Li P.W., Hoskins R.A., Galle R.F.,
RA George R.A., Lewis S.E., Richards S., Ashburner M., Henderson S.N.,
RA Sutton G.G., Wortman J.R., Yandell M.D., Zhang Q., Chen L.X., Brandon R.C.,
RA Rogers Y.-H.C., Blazej R.G., Champe M., Pfeiffer B.D., Wan K.H., Doyle C.,
RA Baxter E.G., Helt G., Nelson C.R., Miklos G.L.G., Abril J.F., Agbayani A.,
RA An H.-J., Andrews-Pfannkoch C., Baldwin D., Ballew R.M., Basu A.,
RA Baxendale J., Bayraktaroglu L., Beasley E.M., Beeson K.Y., Benos P.V.,
RA Berman B.P., Bhandari D., Bolshakov S., Borkova D., Botchan M.R., Bouck J.,
RA Brokstein P., Brottier P., Burtis K.C., Busam D.A., Butler H., Cadieu E.,
RA Center A., Chandra I., Cherry J.M., Cawley S., Dahlke C., Davenport L.B.,
RA Davies P., de Pablos B., Delcher A., Deng Z., Mays A.D., Dew I.,
RA Dietz S.M., Dodson K., Doup L.E., Downes M., Dugan-Rocha S., Dunkov B.C.,
RA Dunn P., Durbin K.J., Evangelista C.C., Ferraz C., Ferriera S.,
RA Fleischmann W., Fosler C., Gabrielian A.E., Garg N.S., Gelbart W.M.,
RA Glasser K., Glodek A., Gong F., Gorrell J.H., Gu Z., Guan P., Harris M.,
RA Harris N.L., Harvey D.A., Heiman T.J., Hernandez J.R., Houck J., Hostin D.,
RA Houston K.A., Howland T.J., Wei M.-H., Ibegwam C., Jalali M., Kalush F.,
RA Karpen G.H., Ke Z., Kennison J.A., Ketchum K.A., Kimmel B.E., Kodira C.D.,
RA Kraft C.L., Kravitz S., Kulp D., Lai Z., Lasko P., Lei Y., Levitsky A.A.,
RA Li J.H., Li Z., Liang Y., Lin X., Liu X., Mattei B., McIntosh T.C.,
RA McLeod M.P., McPherson D., Merkulov G., Milshina N.V., Mobarry C.,
RA Morris J., Moshrefi A., Mount S.M., Moy M., Murphy B., Murphy L.,
RA Muzny D.M., Nelson D.L., Nelson D.R., Nelson K.A., Nixon K., Nusskern D.R.,
RA Pacleb J.M., Palazzolo M., Pittman G.S., Pan S., Pollard J., Puri V.,
RA Reese M.G., Reinert K., Remington K., Saunders R.D.C., Scheeler F.,
RA Shen H., Shue B.C., Siden-Kiamos I., Simpson M., Skupski M.P., Smith T.J.,
RA Spier E., Spradling A.C., Stapleton M., Strong R., Sun E., Svirskas R.,
RA Tector C., Turner R., Venter E., Wang A.H., Wang X., Wang Z.-Y.,
RA Wassarman D.A., Weinstock G.M., Weissenbach J., Williams S.M., Woodage T.,
RA Worley K.C., Wu D., Yang S., Yao Q.A., Ye J., Yeh R.-F., Zaveri J.S.,
RA Zhan M., Zhang G., Zhao Q., Zheng L., Zheng X.H., Zhong F.N., Zhong W.,
RA Zhou X., Zhu S.C., Zhu X., Smith H.O., Gibbs R.A., Myers E.W., Rubin G.M.,
RA Venter J.C.;
RT "The genome sequence of Drosophila melanogaster.";
RL Science 287:2185-2195(2000).
RN [2]
RP GENOME REANNOTATION.
RC STRAIN=Berkeley;
RX PubMed=12537572; DOI=10.1186/gb-2002-3-12-research0083;
RA Misra S., Crosby M.A., Mungall C.J., Matthews B.B., Campbell K.S.,
RA Hradecky P., Huang Y., Kaminker J.S., Millburn G.H., Prochnik S.E.,
RA Smith C.D., Tupy J.L., Whitfield E.J., Bayraktaroglu L., Berman B.P.,
RA Bettencourt B.R., Celniker S.E., de Grey A.D.N.J., Drysdale R.A.,
RA Harris N.L., Richter J., Russo S., Schroeder A.J., Shu S.Q., Stapleton M.,
RA Yamada C., Ashburner M., Gelbart W.M., Rubin G.M., Lewis S.E.;
RT "Annotation of the Drosophila melanogaster euchromatic genome: a systematic
RT review.";
RL Genome Biol. 3:RESEARCH0083.1-RESEARCH0083.22(2002).
RN [3]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC STRAIN=Berkeley;
RA Carlson J.W., Booth B., Frise E., Sandler J., Wan K.H., Yu C.,
RA Celniker S.E.;
RL Submitted (JUN-2009) to the EMBL/GenBank/DDBJ databases.
CC -!- SIMILARITY: Belongs to the TTC36 family. {ECO:0000305}.
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DR EMBL; AE014296; AAF49820.1; -; Genomic_DNA.
DR EMBL; BT088862; ACS78062.1; -; mRNA.
DR RefSeq; NP_648644.1; NM_140387.2.
DR AlphaFoldDB; Q9VU70; -.
DR SMR; Q9VU70; -.
DR BioGRID; 64851; 1.
DR IntAct; Q9VU70; 2.
DR STRING; 7227.FBpp0075591; -.
DR PaxDb; Q9VU70; -.
DR DNASU; 39507; -.
DR EnsemblMetazoa; FBtr0075857; FBpp0075591; FBgn0036359.
DR GeneID; 39507; -.
DR KEGG; dme:Dmel_CG14105; -.
DR UCSC; CG14105-RA; d. melanogaster.
DR FlyBase; FBgn0036359; CG14105.
DR VEuPathDB; VectorBase:FBgn0036359; -.
DR eggNOG; KOG4555; Eukaryota.
DR GeneTree; ENSGT00390000007968; -.
DR HOGENOM; CLU_1464567_0_0_1; -.
DR InParanoid; Q9VU70; -.
DR OMA; PYSALCN; -.
DR OrthoDB; 1597848at2759; -.
DR PhylomeDB; Q9VU70; -.
DR BioGRID-ORCS; 39507; 0 hits in 1 CRISPR screen.
DR GenomeRNAi; 39507; -.
DR PRO; PR:Q9VU70; -.
DR Proteomes; UP000000803; Chromosome 3L.
DR Bgee; FBgn0036359; Expressed in mouthpart and 5 other tissues.
DR Genevisible; Q9VU70; DM.
DR GO; GO:0060271; P:cilium assembly; IBA:GO_Central.
DR Gene3D; 1.25.40.10; -; 1.
DR InterPro; IPR011990; TPR-like_helical_dom_sf.
DR InterPro; IPR019734; TPR_repeat.
DR InterPro; IPR038906; TTC36.
DR PANTHER; PTHR21405; PTHR21405; 1.
DR Pfam; PF13181; TPR_8; 1.
DR SMART; SM00028; TPR; 2.
DR SUPFAM; SSF48452; SSF48452; 1.
DR PROSITE; PS50293; TPR_REGION; 2.
PE 2: Evidence at transcript level;
KW Reference proteome; Repeat; TPR repeat.
FT CHAIN 1..185
FT /note="Tetratricopeptide repeat protein 36 homolog"
FT /id="PRO_0000332187"
FT REPEAT 53..86
FT /note="TPR 1"
FT REPEAT 88..119
FT /note="TPR 2"
FT REPEAT 125..158
FT /note="TPR 3"
SQ SEQUENCE 185 AA; 20667 MW; 3ADA2F6951CA693E CRC64;
MPQANLTLSP HDQQVLDSIF NPLELSSLQT NNLIPAESDL KDEEPDTQAI KASRELELKA
IALSESGELD GALELFQQSL NLAQRASVLN NRAQTLRLAK RDEEALDDLN KALELANDQQ
TRTKCHAHCQ RGVLYRKLDN LEAARADFEA AAQLGSKFAR EQLVEINPYA ALCNQMLRQA
FDQLK
