TTC36_RAT
ID TTC36_RAT Reviewed; 186 AA.
AC Q66H45;
DT 29-APR-2008, integrated into UniProtKB/Swiss-Prot.
DT 11-OCT-2004, sequence version 1.
DT 03-AUG-2022, entry version 106.
DE RecName: Full=Tetratricopeptide repeat protein 36;
DE Short=TPR repeat protein 36;
GN Name=Ttc36;
OS Rattus norvegicus (Rat).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae;
OC Murinae; Rattus.
OX NCBI_TaxID=10116;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC TISSUE=Kidney;
RX PubMed=15489334; DOI=10.1101/gr.2596504;
RG The MGC Project Team;
RT "The status, quality, and expansion of the NIH full-length cDNA project:
RT the Mammalian Gene Collection (MGC).";
RL Genome Res. 14:2121-2127(2004).
RN [2]
RP PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-152, AND IDENTIFICATION BY
RP MASS SPECTROMETRY [LARGE SCALE ANALYSIS].
RX PubMed=22673903; DOI=10.1038/ncomms1871;
RA Lundby A., Secher A., Lage K., Nordsborg N.B., Dmytriyev A., Lundby C.,
RA Olsen J.V.;
RT "Quantitative maps of protein phosphorylation sites across 14 different rat
RT organs and tissues.";
RL Nat. Commun. 3:876-876(2012).
CC -!- SIMILARITY: Belongs to the TTC36 family. {ECO:0000305}.
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DR EMBL; BC082024; AAH82024.1; -; mRNA.
DR RefSeq; NP_001005546.1; NM_001005546.1.
DR AlphaFoldDB; Q66H45; -.
DR SMR; Q66H45; -.
DR STRING; 10116.ENSRNOP00000019933; -.
DR iPTMnet; Q66H45; -.
DR PhosphoSitePlus; Q66H45; -.
DR PaxDb; Q66H45; -.
DR PRIDE; Q66H45; -.
DR GeneID; 300676; -.
DR KEGG; rno:300676; -.
DR UCSC; RGD:1359544; rat.
DR CTD; 143941; -.
DR RGD; 1359544; Ttc36.
DR VEuPathDB; HostDB:ENSRNOG00000014218; -.
DR eggNOG; KOG4555; Eukaryota.
DR HOGENOM; CLU_1464567_0_0_1; -.
DR InParanoid; Q66H45; -.
DR OMA; PYSALCN; -.
DR OrthoDB; 1597848at2759; -.
DR PhylomeDB; Q66H45; -.
DR TreeFam; TF105820; -.
DR PRO; PR:Q66H45; -.
DR Proteomes; UP000002494; Chromosome 8.
DR Bgee; ENSRNOG00000014700; Expressed in adult mammalian kidney and 7 other tissues.
DR Genevisible; Q66H45; RN.
DR GO; GO:0021954; P:central nervous system neuron development; ISO:RGD.
DR GO; GO:0060271; P:cilium assembly; IBA:GO_Central.
DR GO; GO:0007613; P:memory; ISO:RGD.
DR GO; GO:0010801; P:negative regulation of peptidyl-threonine phosphorylation; ISO:RGD.
DR GO; GO:0032435; P:negative regulation of proteasomal ubiquitin-dependent protein catabolic process; ISO:RGD.
DR GO; GO:0032091; P:negative regulation of protein binding; ISO:RGD.
DR GO; GO:1902915; P:negative regulation of protein polyubiquitination; ISO:RGD.
DR GO; GO:0006570; P:tyrosine metabolic process; ISO:RGD.
DR GO; GO:0008542; P:visual learning; ISO:RGD.
DR Gene3D; 1.25.40.10; -; 1.
DR InterPro; IPR011990; TPR-like_helical_dom_sf.
DR InterPro; IPR019734; TPR_repeat.
DR InterPro; IPR038906; TTC36.
DR PANTHER; PTHR21405; PTHR21405; 1.
DR SMART; SM00028; TPR; 3.
DR SUPFAM; SSF48452; SSF48452; 1.
DR PROSITE; PS50005; TPR; 3.
DR PROSITE; PS50293; TPR_REGION; 1.
PE 1: Evidence at protein level;
KW Phosphoprotein; Reference proteome; Repeat; TPR repeat.
FT CHAIN 1..186
FT /note="Tetratricopeptide repeat protein 36"
FT /id="PRO_0000332181"
FT REPEAT 48..81
FT /note="TPR 1"
FT REPEAT 83..115
FT /note="TPR 2"
FT REPEAT 120..153
FT /note="TPR 3"
FT MOD_RES 152
FT /note="Phosphoserine"
FT /evidence="ECO:0007744|PubMed:22673903"
SQ SEQUENCE 186 AA; 20151 MW; 43953CE6CCB8F1EF CRC64;
MGTPNDQAVL QAILNPNTPF GDVVGLDLEE TEEGDEDGVF PQAQLEQSKA LELQGVRAAE
AGDLHTALER FGKAISLLPE RASAYNNRAQ ARRLQGDVAG ALEDLERAVT LSGGRGRAAR
QSFVQRGLLA RFQGRDDDAR RDFEQAARLG SSFARRQLVL LNPYAALCNR MLADMMGQLS
APSNGR
