ID   TTC37_XENLA             Reviewed;        1564 AA.
AC   Q6DFB8;
DT   03-OCT-2006, integrated into UniProtKB/Swiss-Prot.
DT   16-AUG-2004, sequence version 1.
DT   03-AUG-2022, entry version 82.
DE   RecName: Full=Tetratricopeptide repeat protein 37;
DE            Short=TPR repeat protein 37;
DE            Short=Thespin homolog;
GN   Name=ttc37;
OS   Xenopus laevis (African clawed frog).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Amphibia;
OC   Batrachia; Anura; Pipoidea; Pipidae; Xenopodinae; Xenopus; Xenopus.
OX   NCBI_TaxID=8355;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC   TISSUE=Oocyte;
RG   NIH - Xenopus Gene Collection (XGC) project;
RL   Submitted (JUL-2004) to the EMBL/GenBank/DDBJ databases.
CC   ---------------------------------------------------------------------------
CC   Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC   Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC   ---------------------------------------------------------------------------
DR   EMBL; BC076821; AAH76821.1; -; mRNA.
DR   RefSeq; NP_001086571.1; NM_001093102.1.
DR   AlphaFoldDB; Q6DFB8; -.
DR   SMR; Q6DFB8; -.
DR   IntAct; Q6DFB8; 3.
DR   MaxQB; Q6DFB8; -.
DR   PRIDE; Q6DFB8; -.
DR   DNASU; 446406; -.
DR   GeneID; 446406; -.
DR   KEGG; xla:446406; -.
DR   CTD; 446406; -.
DR   Xenbase; XB-GENE-5929219; ttc37.L.
DR   OrthoDB; 347760at2759; -.
DR   Proteomes; UP000186698; Chromosome 1L.
DR   Bgee; 446406; Expressed in muscle tissue and 19 other tissues.
DR   GO; GO:0005737; C:cytoplasm; ISS:UniProtKB.
DR   GO; GO:0000791; C:euchromatin; ISS:UniProtKB.
DR   GO; GO:0005634; C:nucleus; ISS:UniProtKB.
DR   GO; GO:0055087; C:Ski complex; ISS:UniProtKB.
DR   GO; GO:0006401; P:RNA catabolic process; IEA:InterPro.
DR   Gene3D; 1.25.40.10; -; 7.
DR   InterPro; IPR039226; Ski3/TTC37.
DR   InterPro; IPR011990; TPR-like_helical_dom_sf.
DR   InterPro; IPR019734; TPR_repeat.
DR   PANTHER; PTHR15704; PTHR15704; 1.
DR   Pfam; PF13181; TPR_8; 2.
DR   SMART; SM00028; TPR; 16.
DR   SUPFAM; SSF48452; SSF48452; 6.
DR   PROSITE; PS50005; TPR; 13.
DR   PROSITE; PS50293; TPR_REGION; 6.
PE   2: Evidence at transcript level;
KW   Reference proteome; Repeat; TPR repeat.
FT   CHAIN           1..1564
FT                   /note="Tetratricopeptide repeat protein 37"
FT                   /id="PRO_0000251723"
FT   REPEAT          6..39
FT                   /note="TPR 1"
FT   REPEAT          40..73
FT                   /note="TPR 2"
FT   REPEAT          75..110
FT                   /note="TPR 3"
FT   REPEAT          116..149
FT                   /note="TPR 4"
FT   REPEAT          237..271
FT                   /note="TPR 5"
FT   REPEAT          306..339
FT                   /note="TPR 6"
FT   REPEAT          420..453
FT                   /note="TPR 7"
FT   REPEAT          456..492
FT                   /note="TPR 8"
FT   REPEAT          493..527
FT                   /note="TPR 9"
FT   REPEAT          564..597
FT                   /note="TPR 10"
FT   REPEAT          598..631
FT                   /note="TPR 11"
FT   REPEAT          633..665
FT                   /note="TPR 12"
FT   REPEAT          678..713
FT                   /note="TPR 13"
FT   REPEAT          743..776
FT                   /note="TPR 14"
FT   REPEAT          861..894
FT                   /note="TPR 15"
FT   REPEAT          980..1013
FT                   /note="TPR 16"
FT   REPEAT          1020..1050
FT                   /note="TPR 17"
FT   REPEAT          1051..1084
FT                   /note="TPR 18"
FT   REPEAT          1400..1433
FT                   /note="TPR 19"
SQ   SEQUENCE   1564 AA;  175385 MW;  EBAB45B55EDAC437 CRC64;
     MSNKEVKAIL KNARDAIRNK DYKEVLKQCK AVLKLEKNNY NAWVFIGLAA SELEQPDQAQ
     AAYRKAVEIE PDQLLAWQGL GNLYEKVNQK DFKEDLPNVY QKLLELYRSS DKQKWYEICK
     KLSDLYQQEK NYVPAAHTWH QLIKMKEDES IKSNELYPLW KRMTELLSED VEKLDNETQE
     LLLNAFESAI PCIEEIPSEE HQMLYQHYIT CLSKLPLEEA KLKKVCENMI TVYPSLIYPL
     KVLALHYIKS GDITEEAICC YSKLLELDPL NGPGLIGMGI KALHDRNYVL ASENLSKGLK
     DVNCCPSAWC CLAQAQLKIH KYAEALVSCD QAINGATQDN SAPQSVVQKD AAFRLKAEAL
     VEGNSSNNAE EALKALEQIS NADNNPEICA IKGQAYLKKG CIDVASKISE ELRLSHEHLA
     EGHFLEGLLQ YIQKNYSAAE ISLQYALERK PENAVYHYYL GLNYWFMSKE TRRDKTKAVT
     QFLKAAKMDP FMSRAFYYLG HYYSEVAGDK SRARGCYKKA FELDDSDGEA GAAAVDLSME
     LGDMDVALAI LTSVTERADA GTAKWAWLRR GLFYLRVGQH SKSVSDLHAA LRADPKDSNC
     WECLGEAYLS RGGYTTALKS FMKASELNPD SIYSVYKIAS IKQILGTYKE AVNEYQQILM
     KSGEYVPALK GLGECHLMLA KSALSDFLDL KAVDAIEKAI EFLARAIRLR PDLLCLWKLL
     GDACTCIYAV THSSVKVNVL GILLGNDEEQ QLLNKPEVLA LGGRCYGRAL RIQSTANLWC
     DLGINYYYQS QHLMGYDSLT NDASELLEKS QQCIKKAVMV ESGNHQFWNA LGVVSCSKGM
     GNNALAQHAF IKSIHCEQNN VAAWTNLGAL YLMNGNIELS HQAFKVAQSL DPLYVRCWIG
     QALIAETVGS HETMDLFRHT TELSMHVEGA KGYAHWVCTT LQDKNNRNTA LYRYNIVQMN
     AITAAHLALS KYTERIQNDR TAFEMLGYLN EHLNLKKQAS ESYRRVVSIL QEREDKESSN
     SALQHYGRSL CAVGQYQEAI QTFSSTPLTE FDDLTGIALA FFKKGLLQES MKAYKQALSV
     AKSDQEKAHI LTALAIIEYN RGEFDTAKTL LFKCSVLKEP SIESLQSLCA LGLAKRDVTL
     ATAALNELLK HVKIKDNIYE RCLITSAIYV LQGRNEAAQR QACRDIHSHP GNPELWAFLS
     RLVPQHVPRD AKGGAVAGTV AYTLNINHSK KALLYAAVNE LSAGALLADD RKKNALNTLQ
     RAAHFFPDNP AVWASLMAAC EAENTASYLN KKSNKKTDLS LTFLASVKSK TEGMKAVPAS
     YTQTLRSWSL CQAICALKDQ GRISEAEALC TKSIQNCPDQ TPFFLLLRQI QCKQLQSQAQ
     ISEPVLEELK KTVLSNFTSH NAWHWLAEVY QSLGMMMDAE MCYRKSLQLA SQQGNWNGKL
     SSLLRLALLA LKVCMAKIPD SRWPGLLQEA TSEVLKMTFC PLAVLLQGIL QFSTKGSRKT
     RQLLEKVVYQ SGCSDTIAFV ARWYLLRHLH GKNDDQLVEV LLDNAKAHGD TRIIDLHKQL
     TESS