ID   TTC9B_MOUSE             Reviewed;         239 AA.
AC   Q9D6E4; Q8BYN8;
DT   10-JUL-2007, integrated into UniProtKB/Swiss-Prot.
DT   01-JUN-2001, sequence version 1.
DT   03-AUG-2022, entry version 143.
DE   RecName: Full=Tetratricopeptide repeat protein 9B;
DE            Short=TPR repeat protein 9B;
GN   Name=Ttc9b;
OS   Mus musculus (Mouse).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC   Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae;
OC   Murinae; Mus; Mus.
OX   NCBI_TaxID=10090;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC   STRAIN=C57BL/6J; TISSUE=Hippocampus;
RX   PubMed=16141072; DOI=10.1126/science.1112014;
RA   Carninci P., Kasukawa T., Katayama S., Gough J., Frith M.C., Maeda N.,
RA   Oyama R., Ravasi T., Lenhard B., Wells C., Kodzius R., Shimokawa K.,
RA   Bajic V.B., Brenner S.E., Batalov S., Forrest A.R., Zavolan M., Davis M.J.,
RA   Wilming L.G., Aidinis V., Allen J.E., Ambesi-Impiombato A., Apweiler R.,
RA   Aturaliya R.N., Bailey T.L., Bansal M., Baxter L., Beisel K.W., Bersano T.,
RA   Bono H., Chalk A.M., Chiu K.P., Choudhary V., Christoffels A.,
RA   Clutterbuck D.R., Crowe M.L., Dalla E., Dalrymple B.P., de Bono B.,
RA   Della Gatta G., di Bernardo D., Down T., Engstrom P., Fagiolini M.,
RA   Faulkner G., Fletcher C.F., Fukushima T., Furuno M., Futaki S.,
RA   Gariboldi M., Georgii-Hemming P., Gingeras T.R., Gojobori T., Green R.E.,
RA   Gustincich S., Harbers M., Hayashi Y., Hensch T.K., Hirokawa N., Hill D.,
RA   Huminiecki L., Iacono M., Ikeo K., Iwama A., Ishikawa T., Jakt M.,
RA   Kanapin A., Katoh M., Kawasawa Y., Kelso J., Kitamura H., Kitano H.,
RA   Kollias G., Krishnan S.P., Kruger A., Kummerfeld S.K., Kurochkin I.V.,
RA   Lareau L.F., Lazarevic D., Lipovich L., Liu J., Liuni S., McWilliam S.,
RA   Madan Babu M., Madera M., Marchionni L., Matsuda H., Matsuzawa S., Miki H.,
RA   Mignone F., Miyake S., Morris K., Mottagui-Tabar S., Mulder N., Nakano N.,
RA   Nakauchi H., Ng P., Nilsson R., Nishiguchi S., Nishikawa S., Nori F.,
RA   Ohara O., Okazaki Y., Orlando V., Pang K.C., Pavan W.J., Pavesi G.,
RA   Pesole G., Petrovsky N., Piazza S., Reed J., Reid J.F., Ring B.Z.,
RA   Ringwald M., Rost B., Ruan Y., Salzberg S.L., Sandelin A., Schneider C.,
RA   Schoenbach C., Sekiguchi K., Semple C.A., Seno S., Sessa L., Sheng Y.,
RA   Shibata Y., Shimada H., Shimada K., Silva D., Sinclair B., Sperling S.,
RA   Stupka E., Sugiura K., Sultana R., Takenaka Y., Taki K., Tammoja K.,
RA   Tan S.L., Tang S., Taylor M.S., Tegner J., Teichmann S.A., Ueda H.R.,
RA   van Nimwegen E., Verardo R., Wei C.L., Yagi K., Yamanishi H.,
RA   Zabarovsky E., Zhu S., Zimmer A., Hide W., Bult C., Grimmond S.M.,
RA   Teasdale R.D., Liu E.T., Brusic V., Quackenbush J., Wahlestedt C.,
RA   Mattick J.S., Hume D.A., Kai C., Sasaki D., Tomaru Y., Fukuda S.,
RA   Kanamori-Katayama M., Suzuki M., Aoki J., Arakawa T., Iida J., Imamura K.,
RA   Itoh M., Kato T., Kawaji H., Kawagashira N., Kawashima T., Kojima M.,
RA   Kondo S., Konno H., Nakano K., Ninomiya N., Nishio T., Okada M., Plessy C.,
RA   Shibata K., Shiraki T., Suzuki S., Tagami M., Waki K., Watahiki A.,
RA   Okamura-Oho Y., Suzuki H., Kawai J., Hayashizaki Y.;
RT   "The transcriptional landscape of the mammalian genome.";
RL   Science 309:1559-1563(2005).
RN   [2]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC   TISSUE=Brain;
RX   PubMed=15489334; DOI=10.1101/gr.2596504;
RG   The MGC Project Team;
RT   "The status, quality, and expansion of the NIH full-length cDNA project:
RT   the Mammalian Gene Collection (MGC).";
RL   Genome Res. 14:2121-2127(2004).
RN   [3]
RP   PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-7 AND SER-27, AND
RP   IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS].
RC   TISSUE=Brain;
RX   PubMed=21183079; DOI=10.1016/j.cell.2010.12.001;
RA   Huttlin E.L., Jedrychowski M.P., Elias J.E., Goswami T., Rad R.,
RA   Beausoleil S.A., Villen J., Haas W., Sowa M.E., Gygi S.P.;
RT   "A tissue-specific atlas of mouse protein phosphorylation and expression.";
RL   Cell 143:1174-1189(2010).
CC   -!- SIMILARITY: Belongs to the TTC9 family. {ECO:0000305}.
CC   -!- SEQUENCE CAUTION:
CC       Sequence=BAC30153.1; Type=Erroneous initiation; Evidence={ECO:0000305};
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DR   EMBL; AK013779; BAB28991.1; -; mRNA.
DR   EMBL; AK038864; BAC30153.1; ALT_INIT; mRNA.
DR   EMBL; BC089566; AAH89566.1; -; mRNA.
DR   CCDS; CCDS21028.1; -.
DR   RefSeq; NP_082693.1; NM_028417.1.
DR   AlphaFoldDB; Q9D6E4; -.
DR   SMR; Q9D6E4; -.
DR   BioGRID; 215722; 3.
DR   IntAct; Q9D6E4; 1.
DR   STRING; 10090.ENSMUSP00000008088; -.
DR   iPTMnet; Q9D6E4; -.
DR   PhosphoSitePlus; Q9D6E4; -.
DR   MaxQB; Q9D6E4; -.
DR   PaxDb; Q9D6E4; -.
DR   PeptideAtlas; Q9D6E4; -.
DR   PRIDE; Q9D6E4; -.
DR   ProteomicsDB; 298010; -.
DR   Antibodypedia; 30476; 53 antibodies from 15 providers.
DR   Ensembl; ENSMUST00000008088; ENSMUSP00000008088; ENSMUSG00000007944.
DR   GeneID; 73032; -.
DR   KEGG; mmu:73032; -.
DR   UCSC; uc009fwu.1; mouse.
DR   CTD; 148014; -.
DR   MGI; MGI:1920282; Ttc9b.
DR   VEuPathDB; HostDB:ENSMUSG00000007944; -.
DR   eggNOG; ENOG502QQHT; Eukaryota.
DR   GeneTree; ENSGT00940000161494; -.
DR   HOGENOM; CLU_100621_1_0_1; -.
DR   InParanoid; Q9D6E4; -.
DR   OMA; RVREYCF; -.
DR   OrthoDB; 1535136at2759; -.
DR   PhylomeDB; Q9D6E4; -.
DR   TreeFam; TF331917; -.
DR   BioGRID-ORCS; 73032; 5 hits in 72 CRISPR screens.
DR   PRO; PR:Q9D6E4; -.
DR   Proteomes; UP000000589; Chromosome 7.
DR   RNAct; Q9D6E4; protein.
DR   Bgee; ENSMUSG00000007944; Expressed in visual cortex and 76 other tissues.
DR   Genevisible; Q9D6E4; MM.
DR   Gene3D; 1.25.40.10; -; 1.
DR   InterPro; IPR011990; TPR-like_helical_dom_sf.
DR   InterPro; IPR013105; TPR_2.
DR   InterPro; IPR019734; TPR_repeat.
DR   Pfam; PF07719; TPR_2; 1.
DR   SMART; SM00028; TPR; 2.
DR   SUPFAM; SSF48452; SSF48452; 1.
DR   PROSITE; PS50005; TPR; 1.
DR   PROSITE; PS50293; TPR_REGION; 1.
PE   1: Evidence at protein level;
KW   Phosphoprotein; Reference proteome; Repeat; TPR repeat.
FT   CHAIN           1..239
FT                   /note="Tetratricopeptide repeat protein 9B"
FT                   /id="PRO_0000294460"
FT   REPEAT          63..97
FT                   /note="TPR 1"
FT   REPEAT          169..202
FT                   /note="TPR 2"
FT   REGION          1..54
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          98..121
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        13..31
FT                   /note="Pro residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   MOD_RES         7
FT                   /note="Phosphoserine"
FT                   /evidence="ECO:0007744|PubMed:21183079"
FT   MOD_RES         27
FT                   /note="Phosphoserine"
FT                   /evidence="ECO:0007744|PubMed:21183079"
SQ   SEQUENCE   239 AA;  25909 MW;  1C2BF350E54717F6 CRC64;
     MQRGALSPVL MLSAAPEPPP RPPPALSPPG PGSAPRHGSA RSGPAPEPSG GLAAALDSSL
     RAAVAFKAEG QRCYREKKFR EAIGKYHRAL LQLKAAQGAR PGGLPTPSPG PTTSPGPARL
     SEEQRRLVEN TEVECYDSLT ACLLQSELVN YERVREYCLK VLEKQQGNFK ATYRAGIAFY
     HLGDYARALR YLQEARSREP TDTNVLRYIQ LTQLKMNRCS LQREDSDGGT GGPARNVVG