TTC9C_MOUSE
ID TTC9C_MOUSE Reviewed; 171 AA.
AC Q810A3; Q9D7W8;
DT 10-JUL-2007, integrated into UniProtKB/Swiss-Prot.
DT 01-JUN-2003, sequence version 1.
DT 03-AUG-2022, entry version 137.
DE RecName: Full=Tetratricopeptide repeat protein 9C;
DE Short=TPR repeat protein 9C;
GN Name=Ttc9c;
OS Mus musculus (Mouse).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae;
OC Murinae; Mus; Mus.
OX NCBI_TaxID=10090;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC STRAIN=C57BL/6J; TISSUE=Stomach;
RX PubMed=16141072; DOI=10.1126/science.1112014;
RA Carninci P., Kasukawa T., Katayama S., Gough J., Frith M.C., Maeda N.,
RA Oyama R., Ravasi T., Lenhard B., Wells C., Kodzius R., Shimokawa K.,
RA Bajic V.B., Brenner S.E., Batalov S., Forrest A.R., Zavolan M., Davis M.J.,
RA Wilming L.G., Aidinis V., Allen J.E., Ambesi-Impiombato A., Apweiler R.,
RA Aturaliya R.N., Bailey T.L., Bansal M., Baxter L., Beisel K.W., Bersano T.,
RA Bono H., Chalk A.M., Chiu K.P., Choudhary V., Christoffels A.,
RA Clutterbuck D.R., Crowe M.L., Dalla E., Dalrymple B.P., de Bono B.,
RA Della Gatta G., di Bernardo D., Down T., Engstrom P., Fagiolini M.,
RA Faulkner G., Fletcher C.F., Fukushima T., Furuno M., Futaki S.,
RA Gariboldi M., Georgii-Hemming P., Gingeras T.R., Gojobori T., Green R.E.,
RA Gustincich S., Harbers M., Hayashi Y., Hensch T.K., Hirokawa N., Hill D.,
RA Huminiecki L., Iacono M., Ikeo K., Iwama A., Ishikawa T., Jakt M.,
RA Kanapin A., Katoh M., Kawasawa Y., Kelso J., Kitamura H., Kitano H.,
RA Kollias G., Krishnan S.P., Kruger A., Kummerfeld S.K., Kurochkin I.V.,
RA Lareau L.F., Lazarevic D., Lipovich L., Liu J., Liuni S., McWilliam S.,
RA Madan Babu M., Madera M., Marchionni L., Matsuda H., Matsuzawa S., Miki H.,
RA Mignone F., Miyake S., Morris K., Mottagui-Tabar S., Mulder N., Nakano N.,
RA Nakauchi H., Ng P., Nilsson R., Nishiguchi S., Nishikawa S., Nori F.,
RA Ohara O., Okazaki Y., Orlando V., Pang K.C., Pavan W.J., Pavesi G.,
RA Pesole G., Petrovsky N., Piazza S., Reed J., Reid J.F., Ring B.Z.,
RA Ringwald M., Rost B., Ruan Y., Salzberg S.L., Sandelin A., Schneider C.,
RA Schoenbach C., Sekiguchi K., Semple C.A., Seno S., Sessa L., Sheng Y.,
RA Shibata Y., Shimada H., Shimada K., Silva D., Sinclair B., Sperling S.,
RA Stupka E., Sugiura K., Sultana R., Takenaka Y., Taki K., Tammoja K.,
RA Tan S.L., Tang S., Taylor M.S., Tegner J., Teichmann S.A., Ueda H.R.,
RA van Nimwegen E., Verardo R., Wei C.L., Yagi K., Yamanishi H.,
RA Zabarovsky E., Zhu S., Zimmer A., Hide W., Bult C., Grimmond S.M.,
RA Teasdale R.D., Liu E.T., Brusic V., Quackenbush J., Wahlestedt C.,
RA Mattick J.S., Hume D.A., Kai C., Sasaki D., Tomaru Y., Fukuda S.,
RA Kanamori-Katayama M., Suzuki M., Aoki J., Arakawa T., Iida J., Imamura K.,
RA Itoh M., Kato T., Kawaji H., Kawagashira N., Kawashima T., Kojima M.,
RA Kondo S., Konno H., Nakano K., Ninomiya N., Nishio T., Okada M., Plessy C.,
RA Shibata K., Shiraki T., Suzuki S., Tagami M., Waki K., Watahiki A.,
RA Okamura-Oho Y., Suzuki H., Kawai J., Hayashizaki Y.;
RT "The transcriptional landscape of the mammalian genome.";
RL Science 309:1559-1563(2005).
RN [2]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC STRAIN=C57BL/6J; TISSUE=Brain;
RX PubMed=15489334; DOI=10.1101/gr.2596504;
RG The MGC Project Team;
RT "The status, quality, and expansion of the NIH full-length cDNA project:
RT the Mammalian Gene Collection (MGC).";
RL Genome Res. 14:2121-2127(2004).
RN [3]
RP IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS].
RC TISSUE=Brain, Brown adipose tissue, Kidney, Liver, Lung, Spleen, and
RC Testis;
RX PubMed=21183079; DOI=10.1016/j.cell.2010.12.001;
RA Huttlin E.L., Jedrychowski M.P., Elias J.E., Goswami T., Rad R.,
RA Beausoleil S.A., Villen J., Haas W., Sowa M.E., Gygi S.P.;
RT "A tissue-specific atlas of mouse protein phosphorylation and expression.";
RL Cell 143:1174-1189(2010).
CC -!- SIMILARITY: Belongs to the TTC9 family. {ECO:0000305}.
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DR EMBL; AK008753; BAB25875.1; -; mRNA.
DR EMBL; AK169288; BAE41045.1; -; mRNA.
DR EMBL; AK169296; BAE41052.1; -; mRNA.
DR EMBL; BC043061; AAH43061.1; -; mRNA.
DR EMBL; BC058967; AAH58967.1; -; mRNA.
DR CCDS; CCDS29549.1; -.
DR RefSeq; NP_081688.2; NM_027412.3.
DR AlphaFoldDB; Q810A3; -.
DR SMR; Q810A3; -.
DR BioGRID; 214020; 1.
DR STRING; 10090.ENSMUSP00000094513; -.
DR iPTMnet; Q810A3; -.
DR PhosphoSitePlus; Q810A3; -.
DR EPD; Q810A3; -.
DR MaxQB; Q810A3; -.
DR PaxDb; Q810A3; -.
DR PeptideAtlas; Q810A3; -.
DR PRIDE; Q810A3; -.
DR ProteomicsDB; 297750; -.
DR Antibodypedia; 43795; 105 antibodies from 17 providers.
DR DNASU; 70387; -.
DR Ensembl; ENSMUST00000088092; ENSMUSP00000085413; ENSMUSG00000071660.
DR Ensembl; ENSMUST00000096751; ENSMUSP00000094513; ENSMUSG00000071660.
DR GeneID; 70387; -.
DR KEGG; mmu:70387; -.
DR UCSC; uc008gnd.1; mouse.
DR CTD; 283237; -.
DR MGI; MGI:1917637; Ttc9c.
DR VEuPathDB; HostDB:ENSMUSG00000071660; -.
DR eggNOG; ENOG502RXZG; Eukaryota.
DR GeneTree; ENSGT00940000161805; -.
DR HOGENOM; CLU_100621_1_0_1; -.
DR InParanoid; Q810A3; -.
DR OMA; YHQKEKQ; -.
DR OrthoDB; 1535136at2759; -.
DR PhylomeDB; Q810A3; -.
DR TreeFam; TF331917; -.
DR BioGRID-ORCS; 70387; 2 hits in 73 CRISPR screens.
DR ChiTaRS; Ttc9c; mouse.
DR PRO; PR:Q810A3; -.
DR Proteomes; UP000000589; Chromosome 19.
DR RNAct; Q810A3; protein.
DR Bgee; ENSMUSG00000071660; Expressed in manus and 219 other tissues.
DR ExpressionAtlas; Q810A3; baseline and differential.
DR Genevisible; Q810A3; MM.
DR Gene3D; 1.25.40.10; -; 1.
DR InterPro; IPR011990; TPR-like_helical_dom_sf.
DR InterPro; IPR013105; TPR_2.
DR InterPro; IPR019734; TPR_repeat.
DR Pfam; PF07719; TPR_2; 1.
DR SMART; SM00028; TPR; 3.
DR SUPFAM; SSF48452; SSF48452; 1.
DR PROSITE; PS50005; TPR; 2.
DR PROSITE; PS50293; TPR_REGION; 2.
PE 1: Evidence at protein level;
KW Reference proteome; Repeat; TPR repeat.
FT CHAIN 1..171
FT /note="Tetratricopeptide repeat protein 9C"
FT /id="PRO_0000294467"
FT REPEAT 8..41
FT /note="TPR 1"
FT REPEAT 72..107
FT /note="TPR 2"
FT REPEAT 108..141
FT /note="TPR 3"
FT CONFLICT 89
FT /note="N -> Y (in Ref. 1; BAB25875)"
FT /evidence="ECO:0000305"
SQ SEQUENCE 171 AA; 19998 MW; 6BD8AF10567F7B1D CRC64;
MEKRLQEAQV YKEEGNQRYR EGKYRDAVSR YHRALLQLRG LDPSLPSPLS SLGPQGPALT
PEQENILHTI QTHCYNNLAA CLLQMEPVNY ERVREYSQKV LERQPDNAKA LYRAGVAFFH
LQDYDRARHH LLAAVNRQPK DANVRRYLQL TQSELSSYHR KEKQLYLGMF G
