C4S1A_XENLA
ID C4S1A_XENLA Reviewed; 79 AA.
AC Q66KZ1;
DT 20-MAY-2008, integrated into UniProtKB/Swiss-Prot.
DT 11-OCT-2004, sequence version 1.
DT 03-AUG-2022, entry version 60.
DE RecName: Full=CDC42 small effector protein 1-A;
GN Name=cdc42se1-a;
OS Xenopus laevis (African clawed frog).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Amphibia;
OC Batrachia; Anura; Pipoidea; Pipidae; Xenopodinae; Xenopus; Xenopus.
OX NCBI_TaxID=8355;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RG NIH - Xenopus Gene Collection (XGC) project;
RL Submitted (JUL-2004) to the EMBL/GenBank/DDBJ databases.
CC -!- FUNCTION: Probably involved in the organization of the actin
CC cytoskeleton by acting downstream of CDC42, inducing actin filament
CC assembly. {ECO:0000250}.
CC -!- SUBCELLULAR LOCATION: Cytoplasm, cytoskeleton {ECO:0000250}. Cell
CC membrane {ECO:0000250}; Lipid-anchor {ECO:0000250}.
CC -!- SIMILARITY: Belongs to the CDC42SE/SPEC family. {ECO:0000305}.
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DR EMBL; BC078508; AAH78508.1; -; mRNA.
DR RefSeq; NP_001087282.1; NM_001093813.2.
DR RefSeq; XP_018087521.1; XM_018232032.1.
DR AlphaFoldDB; Q66KZ1; -.
DR DNASU; 447104; -.
DR GeneID; 447104; -.
DR KEGG; xla:447104; -.
DR CTD; 447104; -.
DR Xenbase; XB-GENE-6254352; cdc42se1.S.
DR OMA; DRPWNNS; -.
DR OrthoDB; 1646014at2759; -.
DR Proteomes; UP000186698; Chromosome 8S.
DR Bgee; 447104; Expressed in zone of skin and 19 other tissues.
DR GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-KW.
DR GO; GO:0005856; C:cytoskeleton; IEA:UniProtKB-SubCell.
DR GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0031267; F:small GTPase binding; IEA:InterPro.
DR GO; GO:0008360; P:regulation of cell shape; IEA:UniProtKB-KW.
DR GO; GO:0035023; P:regulation of Rho protein signal transduction; IEA:InterPro.
DR Gene3D; 3.90.810.10; -; 1.
DR InterPro; IPR000095; CRIB_dom.
DR InterPro; IPR036936; CRIB_dom_sf.
DR InterPro; IPR039056; SPEC.
DR PANTHER; PTHR13502; PTHR13502; 1.
DR Pfam; PF00786; PBD; 1.
DR PROSITE; PS50108; CRIB; 1.
PE 3: Inferred from homology;
KW Cell membrane; Cell shape; Cytoplasm; Cytoskeleton; Lipoprotein; Membrane;
KW Palmitate; Reference proteome.
FT CHAIN 1..79
FT /note="CDC42 small effector protein 1-A"
FT /id="PRO_0000334635"
FT DOMAIN 30..43
FT /note="CRIB"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00057"
FT LIPID 10
FT /note="S-palmitoyl cysteine"
FT /evidence="ECO:0000250"
FT LIPID 11
FT /note="S-palmitoyl cysteine"
FT /evidence="ECO:0000250"
SQ SEQUENCE 79 AA; 8928 MW; 953DBC3D8361169B CRC64;
MSDFWHKLGC CVVEKPQPKK KRKRIDRSMI GEPMNFVHLT HVGSGDMGAG DGLPMAGTVQ
QQMRSKCGRD RQWSNSRVL