ID   C4S2A_XENTR             Reviewed;          84 AA.
AC   Q28EW5;
DT   20-MAY-2008, integrated into UniProtKB/Swiss-Prot.
DT   04-APR-2006, sequence version 1.
DT   03-AUG-2022, entry version 83.
DE   RecName: Full=CDC42 small effector protein 2-A;
GN   Name=cdc42se2-A; ORFNames=TGas070o22.1;
OS   Xenopus tropicalis (Western clawed frog) (Silurana tropicalis).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Amphibia;
OC   Batrachia; Anura; Pipoidea; Pipidae; Xenopodinae; Xenopus; Silurana.
OX   NCBI_TaxID=8364;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC   TISSUE=Gastrula;
RG   Sanger Xenopus tropicalis EST/cDNA project;
RL   Submitted (OCT-2006) to the EMBL/GenBank/DDBJ databases.
RN   [2]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC   STRAIN=N6; TISSUE=Skin;
RG   NIH - Xenopus Gene Collection (XGC) project;
RL   Submitted (SEP-2006) to the EMBL/GenBank/DDBJ databases.
CC   -!- FUNCTION: Probably involved in the organization of the actin
CC       cytoskeleton by acting downstream of CDC42, inducing actin filament
CC       assembly. {ECO:0000250}.
CC   -!- SUBCELLULAR LOCATION: Cytoplasm, cytoskeleton {ECO:0000250}. Cell
CC       membrane {ECO:0000250}; Lipid-anchor {ECO:0000250}.
CC   -!- SIMILARITY: Belongs to the CDC42SE/SPEC family. {ECO:0000305}.
CC   ---------------------------------------------------------------------------
CC   Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC   Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC   ---------------------------------------------------------------------------
DR   EMBL; CR762307; CAJ82580.1; -; mRNA.
DR   EMBL; BC123961; AAI23962.1; -; mRNA.
DR   RefSeq; NP_001025494.1; NM_001030323.2.
DR   AlphaFoldDB; Q28EW5; -.
DR   STRING; 8364.ENSXETP00000055897; -.
DR   PaxDb; Q28EW5; -.
DR   DNASU; 594909; -.
DR   Ensembl; ENSXETT00000055897; ENSXETP00000055897; ENSXETG00000008962.
DR   GeneID; 594909; -.
DR   KEGG; xtr:594909; -.
DR   CTD; 594909; -.
DR   Xenbase; XB-GENE-5957486; cdc42se2l.
DR   eggNOG; ENOG502S22R; Eukaryota.
DR   HOGENOM; CLU_173417_1_0_1; -.
DR   InParanoid; Q28EW5; -.
DR   OMA; NCCITEQ; -.
DR   OrthoDB; 1646014at2759; -.
DR   PhylomeDB; Q28EW5; -.
DR   TreeFam; TF323815; -.
DR   Reactome; R-XTR-9013148; CDC42 GTPase cycle.
DR   Proteomes; UP000008143; Chromosome 1.
DR   Proteomes; UP000790000; Unplaced.
DR   Bgee; ENSXETG00000008962; Expressed in brain and 13 other tissues.
DR   GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-KW.
DR   GO; GO:0005856; C:cytoskeleton; IEA:UniProtKB-SubCell.
DR   GO; GO:0005886; C:plasma membrane; ISS:UniProtKB.
DR   GO; GO:0031267; F:small GTPase binding; IEA:InterPro.
DR   GO; GO:0008360; P:regulation of cell shape; IEA:UniProtKB-KW.
DR   GO; GO:0035023; P:regulation of Rho protein signal transduction; IEA:InterPro.
DR   GO; GO:0009966; P:regulation of signal transduction; ISS:UniProtKB.
DR   Gene3D; 3.90.810.10; -; 1.
DR   InterPro; IPR000095; CRIB_dom.
DR   InterPro; IPR036936; CRIB_dom_sf.
DR   InterPro; IPR039056; SPEC.
DR   PANTHER; PTHR13502; PTHR13502; 1.
DR   Pfam; PF00786; PBD; 1.
DR   PROSITE; PS50108; CRIB; 1.
PE   3: Inferred from homology;
KW   Cell membrane; Cell shape; Cytoplasm; Cytoskeleton; Lipoprotein; Membrane;
KW   Palmitate; Reference proteome.
FT   CHAIN           1..84
FT                   /note="CDC42 small effector protein 2-A"
FT                   /id="PRO_0000334647"
FT   DOMAIN          29..42
FT                   /note="CRIB"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00057"
FT   LIPID           10
FT                   /note="S-palmitoyl cysteine"
FT                   /evidence="ECO:0000250"
FT   LIPID           11
FT                   /note="S-palmitoyl cysteine"
FT                   /evidence="ECO:0000250"
SQ   SEQUENCE   84 AA;  9271 MW;  C835E82176D95601 CRC64;
     MSEFWLCFNC CIAEQPQPKR RRRIDRSMIG EPTNFVHTAH VGSGDLFSGM NSVSSIQNQM
     QSKGGYGGNM SANVQMQLVD TKAG