ID   C4_VAR67                Reviewed;         316 AA.
AC   P34012;
DT   01-FEB-1994, integrated into UniProtKB/Swiss-Prot.
DT   01-FEB-1996, sequence version 2.
DT   02-JUN-2021, entry version 58.
DE   RecName: Full=Protein C4;
GN   ORFNames=C4L, D11L, D14L;
OS   Variola virus (isolate Human/India/Ind3/1967) (VARV) (Smallpox virus).
OC   Viruses; Varidnaviria; Bamfordvirae; Nucleocytoviricota; Pokkesviricetes;
OC   Chitovirales; Poxviridae; Chordopoxvirinae; Orthopoxvirus.
OX   NCBI_TaxID=587200;
OH   NCBI_TaxID=9606; Homo sapiens (Human).
RN   [1]
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RC   STRAIN=India-1967 / Isolate Ind3;
RX   PubMed=8384129; DOI=10.1016/0014-5793(93)80041-r;
RA   Shchelkunov S.N., Blinov V.M., Sandakhchiev L.S.;
RT   "Genes of variola and vaccinia viruses necessary to overcome the host
RT   protective mechanisms.";
RL   FEBS Lett. 319:80-83(1993).
RN   [2]
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RC   STRAIN=India-1967 / Isolate Ind3;
RX   PubMed=7856312; DOI=10.1016/0168-1702(94)90125-2;
RA   Shchelkunov S.N., Blinov V.M., Resenchuk S.M., Totmenin A.V., Olenina L.V.,
RA   Chirikova G.B., Sandakhchiev L.S.;
RT   "Analysis of the nucleotide sequence of 53 kbp from the right terminus of
RT   the genome of variola major virus strain India-1967.";
RL   Virus Res. 34:207-236(1994).
RN   [3]
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RC   STRAIN=Congo-1965, and Somalia-1977;
RA   Massung R.F., Loparev V.N., Knight J.C., Chizhikov V.E., Parsons J.M.,
RA   Totmenin A.V., Shchelkunov S.N., Esposito J.J.;
RL   Submitted (JUL-1995) to the EMBL/GenBank/DDBJ databases.
CC   -!- SIMILARITY: Belongs to the poxviridae C4/C10 protein family.
CC       {ECO:0000305}.
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DR   EMBL; X69198; CAA48952.1; -; Genomic_DNA.
DR   EMBL; U18337; AAA69316.1; -; Genomic_DNA.
DR   EMBL; U18340; AAA69422.1; -; Genomic_DNA.
DR   PIR; B36838; B36838.
DR   RefSeq; NP_042055.1; NC_001611.1.
DR   PRIDE; P34012; -.
DR   GeneID; 1486391; -.
DR   KEGG; vg:1486391; -.
DR   Proteomes; UP000002060; Genome.
DR   InterPro; IPR005004; Poxvirus_C4/C10.
DR   Pfam; PF03336; Pox_C4_C10; 1.
DR   PIRSF; PIRSF003698; VAC_C10L; 1.
PE   3: Inferred from homology;
KW   Reference proteome.
FT   CHAIN           1..316
FT                   /note="Protein C4"
FT                   /id="PRO_0000099379"
SQ   SEQUENCE   316 AA;  37218 MW;  BEB29064B866F0BB CRC64;
     MDTIKIFNHG EFDTIRNKLV NLLKVVKWNT INSNVTVSST DTIDISNCIR EILYKQFKNV
     RNIEVSSNIS FIKYNRFNDT TLTDDNVGYY LVIYLNRMKS VKTLIYPTPE TVITSSEDIM
     FSKSLNFRFE NVKRDYKLVM CSISLTYKPS ICRIQYDNNK YIDISDSQEG NNLCYCVITM
     DPHHLIDLET ICVLVNKSGK CLLVNEFYTR FRKNHIYDSF ADLCMDHIFE LPDTEELFTL
     RNDDGRNIAW DNDKLESGNN TWIPKTDDEY KFLSKLMNIA KFNNTKFDYY MLVGDTDPCT
     VFTFKVTKYY INLNYE