ID   TTDB_ECOL5              Reviewed;         201 AA.
AC   Q0TD44;
DT   28-NOV-2006, integrated into UniProtKB/Swiss-Prot.
DT   05-SEP-2006, sequence version 1.
DT   25-MAY-2022, entry version 80.
DE   RecName: Full=L(+)-tartrate dehydratase subunit beta;
DE            Short=L-TTD beta;
DE            EC=4.2.1.32;
GN   Name=ttdB; OrderedLocusNames=ECP_3152;
OS   Escherichia coli O6:K15:H31 (strain 536 / UPEC).
OC   Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
OC   Enterobacteriaceae; Escherichia.
OX   NCBI_TaxID=362663;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=536 / UPEC;
RX   PubMed=16879640; DOI=10.1111/j.1365-2958.2006.05255.x;
RA   Hochhut B., Wilde C., Balling G., Middendorf B., Dobrindt U.,
RA   Brzuszkiewicz E., Gottschalk G., Carniel E., Hacker J.;
RT   "Role of pathogenicity island-associated integrases in the genome
RT   plasticity of uropathogenic Escherichia coli strain 536.";
RL   Mol. Microbiol. 61:584-595(2006).
CC   -!- CATALYTIC ACTIVITY:
CC       Reaction=(2R,3R)-tartrate = H2O + oxaloacetate; Xref=Rhea:RHEA:15413,
CC         ChEBI:CHEBI:15377, ChEBI:CHEBI:16452, ChEBI:CHEBI:30924; EC=4.2.1.32;
CC   -!- SUBUNIT: Heterotetramer of two alpha and two beta subunits.
CC       {ECO:0000250}.
CC   -!- INDUCTION: Induced by tartrate, via TtdR. {ECO:0000250}.
CC   -!- SIMILARITY: Belongs to the class-I fumarase family. {ECO:0000305}.
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DR   EMBL; CP000247; ABG71135.1; -; Genomic_DNA.
DR   RefSeq; WP_000722957.1; NC_008253.1.
DR   AlphaFoldDB; Q0TD44; -.
DR   SMR; Q0TD44; -.
DR   STRING; 362663.ECP_3152; -.
DR   EnsemblBacteria; ABG71135; ABG71135; ECP_3152.
DR   GeneID; 67414991; -.
DR   KEGG; ecp:ECP_3152; -.
DR   HOGENOM; CLU_098588_0_0_6; -.
DR   OMA; IYHCGPL; -.
DR   Proteomes; UP000009182; Chromosome.
DR   GO; GO:0008730; F:L(+)-tartrate dehydratase activity; IEA:UniProtKB-EC.
DR   Gene3D; 3.20.130.10; -; 1.
DR   InterPro; IPR004647; Fe-S_hydro-lyase_TtdB-typ_cat.
DR   InterPro; IPR036660; Fe-S_hydroAse_TtdB_cat_sf.
DR   Pfam; PF05683; Fumerase_C; 1.
DR   SUPFAM; SSF117457; SSF117457; 1.
DR   TIGRFAMs; TIGR00723; ttdB_fumA_fumB; 1.
PE   3: Inferred from homology;
KW   Lyase.
FT   CHAIN           1..201
FT                   /note="L(+)-tartrate dehydratase subunit beta"
FT                   /id="PRO_0000262703"
FT   ACT_SITE        37
FT                   /evidence="ECO:0000255"
SQ   SEQUENCE   201 AA;  22679 MW;  E81321CD19A8BE5C CRC64;
     MKKILTTPIK AEDLQDIRVG DVIYLTGTLV TCRDVCHRRL IELKRPIPYD LNGKAIFHAG
     PIVRKNGDKW EMVSVGPTTS MRMESFEREF IEQTGVKLVV GKGGMGPLTE EGCQKFKALH
     VIFPAGCAVL AATQVEEIEE VHWTELGMPE SLWVCRVKEF GPLIVSIDTH GNNLIAENKK
     LFAERRDPIV EEICEHVHYI K