ID   TTDB_ECOL6              Reviewed;         201 AA.
AC   P0AC36; P05851; P33131;
DT   08-NOV-2005, integrated into UniProtKB/Swiss-Prot.
DT   08-NOV-2005, sequence version 1.
DT   03-AUG-2022, entry version 82.
DE   RecName: Full=L(+)-tartrate dehydratase subunit beta;
DE            Short=L-TTD beta;
DE            EC=4.2.1.32;
GN   Name=ttdB; OrderedLocusNames=c3813;
OS   Escherichia coli O6:H1 (strain CFT073 / ATCC 700928 / UPEC).
OC   Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
OC   Enterobacteriaceae; Escherichia.
OX   NCBI_TaxID=199310;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=CFT073 / ATCC 700928 / UPEC;
RX   PubMed=12471157; DOI=10.1073/pnas.252529799;
RA   Welch R.A., Burland V., Plunkett G. III, Redford P., Roesch P., Rasko D.,
RA   Buckles E.L., Liou S.-R., Boutin A., Hackett J., Stroud D., Mayhew G.F.,
RA   Rose D.J., Zhou S., Schwartz D.C., Perna N.T., Mobley H.L.T.,
RA   Donnenberg M.S., Blattner F.R.;
RT   "Extensive mosaic structure revealed by the complete genome sequence of
RT   uropathogenic Escherichia coli.";
RL   Proc. Natl. Acad. Sci. U.S.A. 99:17020-17024(2002).
CC   -!- CATALYTIC ACTIVITY:
CC       Reaction=(2R,3R)-tartrate = H2O + oxaloacetate; Xref=Rhea:RHEA:15413,
CC         ChEBI:CHEBI:15377, ChEBI:CHEBI:16452, ChEBI:CHEBI:30924; EC=4.2.1.32;
CC   -!- SUBUNIT: Heterotetramer of two alpha and two beta subunits.
CC       {ECO:0000305}.
CC   -!- INDUCTION: Induced by tartrate, via TtdR. {ECO:0000250}.
CC   -!- SIMILARITY: Belongs to the class-I fumarase family. {ECO:0000305}.
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DR   EMBL; AE014075; AAN82258.1; -; Genomic_DNA.
DR   RefSeq; WP_000722957.1; NC_004431.1.
DR   AlphaFoldDB; P0AC36; -.
DR   SMR; P0AC36; -.
DR   STRING; 199310.c3813; -.
DR   EnsemblBacteria; AAN82258; AAN82258; c3813.
DR   GeneID; 67414991; -.
DR   KEGG; ecc:c3813; -.
DR   eggNOG; COG1838; Bacteria.
DR   HOGENOM; CLU_098588_0_0_6; -.
DR   OMA; IYHCGPL; -.
DR   BioCyc; ECOL199310:C3813-MON; -.
DR   Proteomes; UP000001410; Chromosome.
DR   GO; GO:0008730; F:L(+)-tartrate dehydratase activity; IEA:UniProtKB-EC.
DR   Gene3D; 3.20.130.10; -; 1.
DR   InterPro; IPR004647; Fe-S_hydro-lyase_TtdB-typ_cat.
DR   InterPro; IPR036660; Fe-S_hydroAse_TtdB_cat_sf.
DR   Pfam; PF05683; Fumerase_C; 1.
DR   SUPFAM; SSF117457; SSF117457; 1.
DR   TIGRFAMs; TIGR00723; ttdB_fumA_fumB; 1.
PE   3: Inferred from homology;
KW   Lyase.
FT   CHAIN           1..201
FT                   /note="L(+)-tartrate dehydratase subunit beta"
FT                   /id="PRO_0000195666"
FT   ACT_SITE        37
FT                   /evidence="ECO:0000255"
SQ   SEQUENCE   201 AA;  22679 MW;  E81321CD19A8BE5C CRC64;
     MKKILTTPIK AEDLQDIRVG DVIYLTGTLV TCRDVCHRRL IELKRPIPYD LNGKAIFHAG
     PIVRKNGDKW EMVSVGPTTS MRMESFEREF IEQTGVKLVV GKGGMGPLTE EGCQKFKALH
     VIFPAGCAVL AATQVEEIEE VHWTELGMPE SLWVCRVKEF GPLIVSIDTH GNNLIAENKK
     LFAERRDPIV EEICEHVHYI K