ID   TTDB_METJA              Reviewed;         195 AA.
AC   Q58034;
DT   01-NOV-1997, integrated into UniProtKB/Swiss-Prot.
DT   01-NOV-1996, sequence version 1.
DT   03-AUG-2022, entry version 113.
DE   RecName: Full=Putative L(+)-tartrate dehydratase subunit beta {ECO:0000250|UniProtKB:P0AC35};
DE            Short=L-TTD beta {ECO:0000250|UniProtKB:P0AC35};
DE            EC=4.2.1.32 {ECO:0000250|UniProtKB:P0AC35};
GN   OrderedLocusNames=MJ0617;
OS   Methanocaldococcus jannaschii (strain ATCC 43067 / DSM 2661 / JAL-1 / JCM
OS   10045 / NBRC 100440) (Methanococcus jannaschii).
OC   Archaea; Euryarchaeota; Methanomada group; Methanococci; Methanococcales;
OC   Methanocaldococcaceae; Methanocaldococcus.
OX   NCBI_TaxID=243232;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 43067 / DSM 2661 / JAL-1 / JCM 10045 / NBRC 100440;
RX   PubMed=8688087; DOI=10.1126/science.273.5278.1058;
RA   Bult C.J., White O., Olsen G.J., Zhou L., Fleischmann R.D., Sutton G.G.,
RA   Blake J.A., FitzGerald L.M., Clayton R.A., Gocayne J.D., Kerlavage A.R.,
RA   Dougherty B.A., Tomb J.-F., Adams M.D., Reich C.I., Overbeek R.,
RA   Kirkness E.F., Weinstock K.G., Merrick J.M., Glodek A., Scott J.L.,
RA   Geoghagen N.S.M., Weidman J.F., Fuhrmann J.L., Nguyen D., Utterback T.R.,
RA   Kelley J.M., Peterson J.D., Sadow P.W., Hanna M.C., Cotton M.D.,
RA   Roberts K.M., Hurst M.A., Kaine B.P., Borodovsky M., Klenk H.-P.,
RA   Fraser C.M., Smith H.O., Woese C.R., Venter J.C.;
RT   "Complete genome sequence of the methanogenic archaeon, Methanococcus
RT   jannaschii.";
RL   Science 273:1058-1073(1996).
CC   -!- CATALYTIC ACTIVITY:
CC       Reaction=(2R,3R)-tartrate = H2O + oxaloacetate; Xref=Rhea:RHEA:15413,
CC         ChEBI:CHEBI:15377, ChEBI:CHEBI:16452, ChEBI:CHEBI:30924; EC=4.2.1.32;
CC         Evidence={ECO:0000250|UniProtKB:P0AC35};
CC   -!- SUBUNIT: Heterotetramer of two alpha and two beta subunits.
CC       {ECO:0000250|UniProtKB:P0AC35}.
CC   -!- SIMILARITY: Belongs to the class-I fumarase family. {ECO:0000305}.
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DR   EMBL; L77117; AAB98612.1; -; Genomic_DNA.
DR   PIR; A64377; A64377.
DR   RefSeq; WP_010870122.1; NC_000909.1.
DR   PDB; 5DNI; X-ray; 2.30 A; A/B=1-179.
DR   PDBsum; 5DNI; -.
DR   AlphaFoldDB; Q58034; -.
DR   SMR; Q58034; -.
DR   STRING; 243232.MJ_0617; -.
DR   EnsemblBacteria; AAB98612; AAB98612; MJ_0617.
DR   GeneID; 1451483; -.
DR   KEGG; mja:MJ_0617; -.
DR   eggNOG; arCOG04406; Archaea.
DR   HOGENOM; CLU_098588_0_0_2; -.
DR   InParanoid; Q58034; -.
DR   OMA; IYHCGPL; -.
DR   OrthoDB; 88282at2157; -.
DR   PhylomeDB; Q58034; -.
DR   Proteomes; UP000000805; Chromosome.
DR   GO; GO:0008730; F:L(+)-tartrate dehydratase activity; IEA:UniProtKB-EC.
DR   Gene3D; 3.20.130.10; -; 1.
DR   InterPro; IPR004647; Fe-S_hydro-lyase_TtdB-typ_cat.
DR   InterPro; IPR036660; Fe-S_hydroAse_TtdB_cat_sf.
DR   Pfam; PF05683; Fumerase_C; 1.
DR   SUPFAM; SSF117457; SSF117457; 1.
DR   TIGRFAMs; TIGR00723; ttdB_fumA_fumB; 1.
PE   1: Evidence at protein level;
KW   3D-structure; Lyase; Reference proteome.
FT   CHAIN           1..195
FT                   /note="Putative L(+)-tartrate dehydratase subunit beta"
FT                   /id="PRO_0000195662"
FT   ACT_SITE        36
FT                   /evidence="ECO:0000255"
FT   BINDING         104
FT                   /ligand="substrate"
FT                   /evidence="ECO:0000255"
FT   STRAND          2..7
FT                   /evidence="ECO:0007829|PDB:5DNI"
FT   HELIX           10..15
FT                   /evidence="ECO:0007829|PDB:5DNI"
FT   STRAND          21..30
FT                   /evidence="ECO:0007829|PDB:5DNI"
FT   HELIX           33..44
FT                   /evidence="ECO:0007829|PDB:5DNI"
FT   STRAND          57..59
FT                   /evidence="ECO:0007829|PDB:5DNI"
FT   STRAND          64..68
FT                   /evidence="ECO:0007829|PDB:5DNI"
FT   STRAND          71..76
FT                   /evidence="ECO:0007829|PDB:5DNI"
FT   HELIX           82..85
FT                   /evidence="ECO:0007829|PDB:5DNI"
FT   TURN            86..88
FT                   /evidence="ECO:0007829|PDB:5DNI"
FT   HELIX           89..96
FT                   /evidence="ECO:0007829|PDB:5DNI"
FT   STRAND          100..105
FT                   /evidence="ECO:0007829|PDB:5DNI"
FT   HELIX           111..118
FT                   /evidence="ECO:0007829|PDB:5DNI"
FT   STRAND          121..124
FT                   /evidence="ECO:0007829|PDB:5DNI"
FT   HELIX           130..133
FT                   /evidence="ECO:0007829|PDB:5DNI"
FT   HELIX           134..136
FT                   /evidence="ECO:0007829|PDB:5DNI"
FT   STRAND          137..145
FT                   /evidence="ECO:0007829|PDB:5DNI"
FT   HELIX           146..149
FT                   /evidence="ECO:0007829|PDB:5DNI"
FT   TURN            151..153
FT                   /evidence="ECO:0007829|PDB:5DNI"
FT   STRAND          154..170
FT                   /evidence="ECO:0007829|PDB:5DNI"
SQ   SEQUENCE   195 AA;  21868 MW;  A5FDEB0E77D00902 CRC64;
     MEYTFNKLTK KDVKKLKVGD IVYLNGKIYT ARDEAHLKII EMLKSNEKLP FDLNESIIYH
     AGPIMKKVND SWVCVSIGPT TSARMNDVEE EFIKLTNISA IVGKGGMKKE LLKTFEDYGV
     VYLAAPGGCA ALLANSVKRV DNVYFLDELG MPEAVWELEV NNFGPLIVAM DSHGNSIYEE
     VNKKVYEKLN ELIGL