ID   TTGC_PSEPK              Reviewed;         484 AA.
AC   Q88N32;
DT   19-JUL-2005, integrated into UniProtKB/Swiss-Prot.
DT   01-JUN-2003, sequence version 1.
DT   03-AUG-2022, entry version 98.
DE   RecName: Full=Probable efflux pump outer membrane protein TtgC;
DE   Flags: Precursor;
GN   Name=ttgC; OrderedLocusNames=PP_1384;
OS   Pseudomonas putida (strain ATCC 47054 / DSM 6125 / CFBP 8728 / NCIMB 11950
OS   / KT2440).
OC   Bacteria; Proteobacteria; Gammaproteobacteria; Pseudomonadales;
OC   Pseudomonadaceae; Pseudomonas.
OX   NCBI_TaxID=160488;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 47054 / DSM 6125 / CFBP 8728 / NCIMB 11950 / KT2440;
RX   PubMed=12534463; DOI=10.1046/j.1462-2920.2002.00366.x;
RA   Nelson K.E., Weinel C., Paulsen I.T., Dodson R.J., Hilbert H.,
RA   Martins dos Santos V.A.P., Fouts D.E., Gill S.R., Pop M., Holmes M.,
RA   Brinkac L.M., Beanan M.J., DeBoy R.T., Daugherty S.C., Kolonay J.F.,
RA   Madupu R., Nelson W.C., White O., Peterson J.D., Khouri H.M., Hance I.,
RA   Chris Lee P., Holtzapple E.K., Scanlan D., Tran K., Moazzez A.,
RA   Utterback T.R., Rizzo M., Lee K., Kosack D., Moestl D., Wedler H.,
RA   Lauber J., Stjepandic D., Hoheisel J., Straetz M., Heim S., Kiewitz C.,
RA   Eisen J.A., Timmis K.N., Duesterhoeft A., Tuemmler B., Fraser C.M.;
RT   "Complete genome sequence and comparative analysis of the metabolically
RT   versatile Pseudomonas putida KT2440.";
RL   Environ. Microbiol. 4:799-808(2002).
RN   [2]
RP   CHARACTERIZATION.
RX   PubMed=12743835; DOI=10.1007/s00792-003-0331-x;
RA   Segura A., Rojas A., Hurtado A., Huertas M.J., Ramos J.L.;
RT   "Comparative genomic analysis of solvent extrusion pumps in Pseudomonas
RT   strains exhibiting different degrees of solvent tolerance.";
RL   Extremophiles 7:371-376(2003).
CC   -!- FUNCTION: Probable outer membrane component of the TtgABC efflux pump
CC       with unknown specificity.
CC   -!- SUBCELLULAR LOCATION: Cell outer membrane {ECO:0000305}; Lipid-anchor
CC       {ECO:0000255|PROSITE-ProRule:PRU00303}.
CC   -!- SIMILARITY: Belongs to the outer membrane factor (OMF) (TC 1.B.17)
CC       family. {ECO:0000305}.
CC   -!- CAUTION: There are 4 nearly identical operons in various strains of
CC       P.putida. The ttgABC operon of strain DOT-T1E and the mepABC operon of
CC       strain KT2442-TOL function in solvent and antibiotic efflux; however in
CC       strain S12 the arpABC operon functions only in antibiotic efflux. This
CC       may be due to different protein expression levels. In KT2400 this
CC       operon does not seem to function in toluene efflux. {ECO:0000305}.
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DR   EMBL; AE015451; AAN67007.1; -; Genomic_DNA.
DR   RefSeq; NP_743543.1; NC_002947.4.
DR   RefSeq; WP_010952492.1; NC_002947.4.
DR   AlphaFoldDB; Q88N32; -.
DR   SMR; Q88N32; -.
DR   STRING; 160488.PP_1384; -.
DR   EnsemblBacteria; AAN67007; AAN67007; PP_1384.
DR   KEGG; ppu:PP_1384; -.
DR   PATRIC; fig|160488.4.peg.1468; -.
DR   eggNOG; COG1538; Bacteria.
DR   HOGENOM; CLU_012817_13_3_6; -.
DR   OMA; AANQDYY; -.
DR   PhylomeDB; Q88N32; -.
DR   BioCyc; PPUT160488:G1G01-1474-MON; -.
DR   Proteomes; UP000000556; Chromosome.
DR   GO; GO:0009279; C:cell outer membrane; IEA:UniProtKB-SubCell.
DR   GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR   GO; GO:0015562; F:efflux transmembrane transporter activity; IEA:InterPro.
DR   InterPro; IPR003423; OMP_efflux.
DR   InterPro; IPR010131; RND_efflux_OM_lipoprot_NodT.
DR   Pfam; PF02321; OEP; 2.
DR   TIGRFAMs; TIGR01845; outer_NodT; 1.
DR   PROSITE; PS51257; PROKAR_LIPOPROTEIN; 1.
PE   1: Evidence at protein level;
KW   Cell outer membrane; Lipoprotein; Membrane; Palmitate; Reference proteome;
KW   Signal; Transmembrane; Transmembrane beta strand; Transport.
FT   SIGNAL          1..17
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00303"
FT   CHAIN           18..484
FT                   /note="Probable efflux pump outer membrane protein TtgC"
FT                   /id="PRO_0000031001"
FT   LIPID           18
FT                   /note="N-palmitoyl cysteine"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00303"
FT   LIPID           18
FT                   /note="S-diacylglycerol cysteine"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00303"
SQ   SEQUENCE   484 AA;  52864 MW;  FFD6E78FBC55C678 CRC64;
     MTKSLLSLAV TAFILGGCSL IPDYQTPEAP VAAQWPQGPA YSPTQSADVA AAEQGWRQFF
     HDPALQQLIQ TSLVNNRDLR VAALNLDAYR AQYRIQRADL FPAVSATGSG SRQRVPANMS
     QTGESGITSQ YSATLGVSAY ELDLFGRVRS LTEQALETYL SSEQARRSTQ IALVASVANA
     YYTWQADQAL FKLTEETLKT YEESYNLTRR SNEVGVASAL DVSQARTAVE GARVKYSQYQ
     RLVAQDVNSL TVLLGTGIPA DLAKPLELDA DQLAEVPAGL PSDILQRRPD IQEAEHLLKA
     ANANIGAARA AFFPSISLTA NAGSLSPDMG HLFSGGQGTW LFQPQINLPI FNAGSLKASL
     DYSKIQKDIN VAKYEKTIQT AFQEVSDGLA ARKTFEEQLQ AQRDLVQANQ DYYRLAERRY
     RIGIDSNLTF LDAQRNLFSA QQALIGDRLS QLTSEVNLYK ALGGGWYEQT GQANQQASVE
     TPKG