ID   TTR1_CAEEL              Reviewed;         156 AA.
AC   P34502;
DT   01-FEB-1994, integrated into UniProtKB/Swiss-Prot.
DT   01-FEB-1994, sequence version 1.
DT   03-AUG-2022, entry version 114.
DE   RecName: Full=Transthyretin-like protein 1;
DE   Flags: Precursor;
GN   Name=ttr-1; ORFNames=K03H1.6;
OS   Caenorhabditis elegans.
OC   Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida;
OC   Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae;
OC   Caenorhabditis.
OX   NCBI_TaxID=6239;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=Bristol N2;
RX   PubMed=7906398; DOI=10.1038/368032a0;
RA   Wilson R., Ainscough R., Anderson K., Baynes C., Berks M., Bonfield J.,
RA   Burton J., Connell M., Copsey T., Cooper J., Coulson A., Craxton M.,
RA   Dear S., Du Z., Durbin R., Favello A., Fraser A., Fulton L., Gardner A.,
RA   Green P., Hawkins T., Hillier L., Jier M., Johnston L., Jones M.,
RA   Kershaw J., Kirsten J., Laisster N., Latreille P., Lightning J., Lloyd C.,
RA   Mortimore B., O'Callaghan M., Parsons J., Percy C., Rifken L., Roopra A.,
RA   Saunders D., Shownkeen R., Sims M., Smaldon N., Smith A., Smith M.,
RA   Sonnhammer E., Staden R., Sulston J., Thierry-Mieg J., Thomas K.,
RA   Vaudin M., Vaughan K., Waterston R., Watson A., Weinstock L.,
RA   Wilkinson-Sproat J., Wohldman P.;
RT   "2.2 Mb of contiguous nucleotide sequence from chromosome III of C.
RT   elegans.";
RL   Nature 368:32-38(1994).
RN   [2]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=Bristol N2;
RX   PubMed=9851916; DOI=10.1126/science.282.5396.2012;
RG   The C. elegans sequencing consortium;
RT   "Genome sequence of the nematode C. elegans: a platform for investigating
RT   biology.";
RL   Science 282:2012-2018(1998).
RN   [3]
RP   GLYCOSYLATION [LARGE SCALE ANALYSIS] AT ASN-151, AND IDENTIFICATION BY MASS
RP   SPECTROMETRY.
RC   STRAIN=Bristol N2;
RX   PubMed=17761667; DOI=10.1074/mcp.m600392-mcp200;
RA   Kaji H., Kamiie J., Kawakami H., Kido K., Yamauchi Y., Shinkawa T.,
RA   Taoka M., Takahashi N., Isobe T.;
RT   "Proteomics reveals N-linked glycoprotein diversity in Caenorhabditis
RT   elegans and suggests an atypical translocation mechanism for integral
RT   membrane proteins.";
RL   Mol. Cell. Proteomics 6:2100-2109(2007).
CC   -!- SUBCELLULAR LOCATION: Secreted {ECO:0000305}.
CC   -!- SIMILARITY: Belongs to the nematode transthyretin-like family.
CC       {ECO:0000305}.
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DR   EMBL; Z29560; CAA82658.1; -; Genomic_DNA.
DR   PIR; S41029; S41029.
DR   RefSeq; NP_499204.1; NM_066803.4.
DR   AlphaFoldDB; P34502; -.
DR   SMR; P34502; -.
DR   BioGRID; 51666; 1.
DR   STRING; 6239.K03H1.6; -.
DR   iPTMnet; P34502; -.
DR   EPD; P34502; -.
DR   PaxDb; P34502; -.
DR   PeptideAtlas; P34502; -.
DR   EnsemblMetazoa; K03H1.6.1; K03H1.6.1; WBGene00010541.
DR   GeneID; 186958; -.
DR   KEGG; cel:CELE_K03H1.6; -.
DR   UCSC; K03H1.6; c. elegans.
DR   CTD; 186958; -.
DR   WormBase; K03H1.6; CE00476; WBGene00010541; ttr-1.
DR   eggNOG; ENOG502TFEY; Eukaryota.
DR   GeneTree; ENSGT00970000196570; -.
DR   HOGENOM; CLU_121109_4_1_1; -.
DR   InParanoid; P34502; -.
DR   OMA; RSCAYRN; -.
DR   OrthoDB; 1525729at2759; -.
DR   PhylomeDB; P34502; -.
DR   PRO; PR:P34502; -.
DR   Proteomes; UP000001940; Chromosome III.
DR   Bgee; WBGene00010541; Expressed in larva and 3 other tissues.
DR   GO; GO:0009986; C:cell surface; IEA:InterPro.
DR   GO; GO:0005576; C:extracellular region; IEA:UniProtKB-SubCell.
DR   Gene3D; 2.60.40.3330; -; 1.
DR   InterPro; IPR001534; Transthyretin-like.
DR   InterPro; IPR038479; Transthyretin-like_sf.
DR   PANTHER; PTHR21700; PTHR21700; 1.
DR   Pfam; PF01060; TTR-52; 1.
PE   1: Evidence at protein level;
KW   Glycoprotein; Reference proteome; Secreted; Signal.
FT   SIGNAL          1..17
FT                   /evidence="ECO:0000255"
FT   CHAIN           18..156
FT                   /note="Transthyretin-like protein 1"
FT                   /id="PRO_0000036253"
FT   CARBOHYD        151
FT                   /note="N-linked (GlcNAc...) asparagine"
FT                   /evidence="ECO:0000269|PubMed:17761667"
SQ   SEQUENCE   156 AA;  16858 MW;  AB2C4FB7B52C584F CRC64;
     MKIALSFLFL TSTFSNAGKI GRLQSVAVSG QLNCLGKPAV GVRIDLMESD NNGEETGIID
     DNDFMGYTYT DSAGFFNMSG SEVEISGIEP YVNIFHKCND GLSPCQRQLR VDIPKSATAS
     GPAPNETFSI GTLELSSRKV IGERRSCAYR NLTQTS