ID   TTR2_CAEEL              Reviewed;         148 AA.
AC   P34500;
DT   01-FEB-1994, integrated into UniProtKB/Swiss-Prot.
DT   01-FEB-1994, sequence version 1.
DT   03-AUG-2022, entry version 113.
DE   RecName: Full=Transthyretin-like protein 2;
DE   Flags: Precursor;
GN   Name=ttr-2; ORFNames=K03H1.4;
OS   Caenorhabditis elegans.
OC   Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida;
OC   Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae;
OC   Caenorhabditis.
OX   NCBI_TaxID=6239;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=Bristol N2;
RX   PubMed=7906398; DOI=10.1038/368032a0;
RA   Wilson R., Ainscough R., Anderson K., Baynes C., Berks M., Bonfield J.,
RA   Burton J., Connell M., Copsey T., Cooper J., Coulson A., Craxton M.,
RA   Dear S., Du Z., Durbin R., Favello A., Fraser A., Fulton L., Gardner A.,
RA   Green P., Hawkins T., Hillier L., Jier M., Johnston L., Jones M.,
RA   Kershaw J., Kirsten J., Laisster N., Latreille P., Lightning J., Lloyd C.,
RA   Mortimore B., O'Callaghan M., Parsons J., Percy C., Rifken L., Roopra A.,
RA   Saunders D., Shownkeen R., Sims M., Smaldon N., Smith A., Smith M.,
RA   Sonnhammer E., Staden R., Sulston J., Thierry-Mieg J., Thomas K.,
RA   Vaudin M., Vaughan K., Waterston R., Watson A., Weinstock L.,
RA   Wilkinson-Sproat J., Wohldman P.;
RT   "2.2 Mb of contiguous nucleotide sequence from chromosome III of C.
RT   elegans.";
RL   Nature 368:32-38(1994).
RN   [2]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=Bristol N2;
RX   PubMed=9851916; DOI=10.1126/science.282.5396.2012;
RG   The C. elegans sequencing consortium;
RT   "Genome sequence of the nematode C. elegans: a platform for investigating
RT   biology.";
RL   Science 282:2012-2018(1998).
RN   [3]
RP   GLYCOSYLATION [LARGE SCALE ANALYSIS] AT ASN-77, AND IDENTIFICATION BY MASS
RP   SPECTROMETRY.
RC   STRAIN=Bristol N2;
RX   PubMed=17761667; DOI=10.1074/mcp.m600392-mcp200;
RA   Kaji H., Kamiie J., Kawakami H., Kido K., Yamauchi Y., Shinkawa T.,
RA   Taoka M., Takahashi N., Isobe T.;
RT   "Proteomics reveals N-linked glycoprotein diversity in Caenorhabditis
RT   elegans and suggests an atypical translocation mechanism for integral
RT   membrane proteins.";
RL   Mol. Cell. Proteomics 6:2100-2109(2007).
CC   -!- SUBCELLULAR LOCATION: Secreted {ECO:0000305}.
CC   -!- SIMILARITY: Belongs to the nematode transthyretin-like family.
CC       {ECO:0000305}.
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DR   EMBL; Z29560; CAA82657.1; -; Genomic_DNA.
DR   PIR; S41027; S41027.
DR   RefSeq; NP_499203.1; NM_066802.6.
DR   AlphaFoldDB; P34500; -.
DR   SMR; P34500; -.
DR   BioGRID; 41597; 3.
DR   STRING; 6239.K03H1.4.2; -.
DR   iPTMnet; P34500; -.
DR   EPD; P34500; -.
DR   PaxDb; P34500; -.
DR   PeptideAtlas; P34500; -.
DR   EnsemblMetazoa; K03H1.4.1; K03H1.4.1; WBGene00010539.
DR   GeneID; 176403; -.
DR   KEGG; cel:CELE_K03H1.4; -.
DR   CTD; 176403; -.
DR   WormBase; K03H1.4; CE00475; WBGene00010539; ttr-2.
DR   eggNOG; ENOG502S1IK; Eukaryota.
DR   GeneTree; ENSGT00970000196570; -.
DR   HOGENOM; CLU_121109_4_1_1; -.
DR   InParanoid; P34500; -.
DR   OMA; PCQRVFR; -.
DR   OrthoDB; 1412342at2759; -.
DR   PhylomeDB; P34500; -.
DR   PRO; PR:P34500; -.
DR   Proteomes; UP000001940; Chromosome III.
DR   Bgee; WBGene00010539; Expressed in adult organism and 4 other tissues.
DR   GO; GO:0009986; C:cell surface; IEA:InterPro.
DR   GO; GO:0005576; C:extracellular region; IEA:UniProtKB-SubCell.
DR   Gene3D; 2.60.40.3330; -; 1.
DR   InterPro; IPR001534; Transthyretin-like.
DR   InterPro; IPR038479; Transthyretin-like_sf.
DR   PANTHER; PTHR21700; PTHR21700; 1.
DR   Pfam; PF01060; TTR-52; 1.
PE   1: Evidence at protein level;
KW   Glycoprotein; Reference proteome; Secreted; Signal.
FT   SIGNAL          1..17
FT                   /evidence="ECO:0000255"
FT   CHAIN           18..148
FT                   /note="Transthyretin-like protein 2"
FT                   /id="PRO_0000036252"
FT   CARBOHYD        77
FT                   /note="N-linked (GlcNAc...) asparagine"
FT                   /evidence="ECO:0000269|PubMed:17761667"
SQ   SEQUENCE   148 AA;  15703 MW;  587CE4D50BB43DC0 CRC64;
     MSKYAILGLV LVGTVASLDF IGRTQSAAIK GRLVCEGKPA SGVKVKLMES DNSFGPGFLD
     SDDKMASGKA DSHGEFNLSG STKEITGIEP YLVVFHDCKD GITPCQRVFR VNVPKSYTNS
     GSSAKKTYDA GVIELAGKYP GETRSCLN